Award Data

TBD

Major organ injury such as liver, kidney, heart and lung injuries can lead to high morbidity and mortality in critically ill patients. Advanced noninvasive testing with high sensitivity and specificity is needed to detect specific organ injury particularly at early stages. Current techniques such as PCR, MS, absorption-based assays, ELISA and microfluidic-Luminex, cannot meet such requirements. To ...

Platelets play a central role in hemostasis and are responsible for many inherited and acquired bleeding disorders and thrombic events in human beings. A significant portion of post-trauma deaths are related to coagulopathy or hemorrhage events for both injured soldiers and civilian patients. Several platelet function analyzers have been designed and developed; however due to form-factor and/or ...

Burn injuries constitute 5-20% of combat casualties during conventional warfare. Nonviable tissue within the burn predisposes it to microbial colonization and subsequent infection. The goal of burn care, especially at early echelons, is to control infection until the injury either spontaneously heals or is surgically closed. Prevention of infection is crucial for patient survival and to reduce ...

HemoSonics LLC is developing an easy to use and easy to interpret diagnostic device to rapidly identify diffuse coagulopathies in order to guide proper and evidence-based interventions. The management of diffuse coagulopathies is extremely important in military medicine as these conditions represent a significant source of combat morbidity and mortality. HemoSonics"device is based on sonorheome ...

Many emergency cricothyrotomy kits have been developed in an attempt to simplify this potentially life-saving medical procedure. However, none of the existing kits perform noticeably better than the standard surgical kit. The standard kit itself has led to a reported failure rate of 33% when performed in combat environments, and airway obstruction is reported to be the third most preventable cau ...

It is estimated that 20 percent of returning forces from the Iraq and Afghanistan wars are afflicted with PTSD or major depression. In the last year alone, over 400,000 military veterans have been diagnosed with PTSD. Among troops still in the military, experts estimate that one in five has experienced acute stress, anxiety, depression, or other mental health issues as a result of war-zone deploym ...

Bioassays employed to assess the diverse range of toxicity associated with organ injury are time-consuming, costly and require multiple instruments and testing formats (i.e. fluorescence-based capture, ELISAs, PCR, etc.) to reach a diagnosis. These platforms are incapable of predicting the onset of irreversible organ (e.g. kidney, liver, heart and lung) tissue injury. If a single multiplexed scree ...

With the advent of improved body armor and vehicles and the enemy"s use of the improved explosion device (IED) in the most recent conflicts, blast injuries and related burns to the face have become more and more common among our Wounded Warriors. Pathological scarring, which often results in contracture, tends to be more prevalent in these burn cases due to the traumatic nature of the IED injury. ...

PsiKick and Bionic Skins LLC will collaborate in this proposal to develop the eBionicskins system, an advanced instrumented prosthetic liner for monitoring the tissue interface within a prosthetic socket using a wireless sensing platform. PsiKick"s ultra-low power electronics fit neatly within Bionic Skins"vision for a complete redesign of prosthetic sockets with a variable-compliant interface th ...