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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Ambient light activatable opsin based therapy for age-related macular degeneration

    SBC: NANOSCOPE TECHNOLOGIES LLC            Topic: N

    DESCRIPTION provided by applicant Severe loss of vision occurs due to age related macular degeneration AMD and approximately million people in the US have some form of AMD which is expected to double by Most of the current clinical treatments are primarily focused on slowing down the progression of the disease as there is neither a cure that can stop the degeneration nor a therapy ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Targeted Transcranial Electrotherapy to accelerate Stroke Rehabilitation-Exploratory Trial on Aphasia

    SBC: SOTERIX MEDICAL INC            Topic: NINDS

    DESCRIPTION provided by applicant Transcranial Direct Current Stimulation tDCS with weak currents is a non invasive low cost and well tolerated technique producing lasting functional changes in the central nervous system There is increasing evidence supporting the use of tDCS to improve stroke rehabilitation Behavioral and therapeutic outcomes of tDCS depend on the brain areas being targe ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Primary Prevention of Sexual Violence among College Students

    SBC: National Health Promotion Associates, Inc.            Topic: R44

    DESCRIPTION provided by applicant Primary Prevention of Sexual Violence among College Students This Fast Track SBIR proposal is designed to address the urgent need for an effective primary prevention approach to the problem of sexual violence among college students It is estimated that in every college women has been sexually assaulted while in college There is a dearth of primary preven ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. IND- and NDA-enabling toxicology studies for PTI-125, a novel small molecule for Alzheimer's disease

    SBC: PAIN THERAPEUTICS, INC.            Topic: NIA

    DESCRIPTION provided by applicant PTI is a novel compound with a novel target designed to treat and slow the progression of Alzheimerandapos s disease AD PTI works by binding extremely tightly to a particular site on filamin A FLNA a protein we recently demonstrated to be critical to beta amyloidandapos s toxicity Beta amyloid A exerts its toxic effects by binding and h ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. High-Throughput Manufacturing Methods for Engineered MRI Contrast Agents

    SBC: ADVANCED RESEARCH CORPORATION            Topic: 9010368R

    This project focuses on developing a magnetic resonance imaging (MRI) contrast agent that may increase the detection of tagged cells by a factor of 10-100. The ability to noninvasively track specifically labeled (tagged) cells, enables a researcher or medical treatment professional to dynamically monitor the delivery and targeted application of medicinal and bio-reactive agents.

    SBIR Phase I 2015 Department of CommerceNational Institute of Standards and Technology
  6. A Tool for Building Semantically Interoperable Specification and Standards

    SBC: XSB INC            Topic: 9010273R

    Standards and specifications are widely used in government and industry to define requirements for products and processes and insure interoperability, safety, and quality of industrial and domestic products. Specifications and standards documents almost always cross-reference other standards and specification. Taken together, the web of interdependent standards forms an immensely important knowled ...

    SBIR Phase I 2015 Department of CommerceNational Institute of Standards and Technology
  7. Biocompatible retinal prosthesis based on a conjugated polymer photoactive layer

    SBC: LYNNTECH INC.            Topic: N

    DESCRIPTION provided by applicant This proposal is in response to a specific approved topic area as defined by the NEI in Appendix A National Institutes of Health SBA Approved SBIR STTR Topics for Awards over Statutory Budget Limitations from the PHS Omnibus Solicitation for SBIR STTR Grant Applications This Phase I feasibility study is an advanced technology project with a clearly id ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Precise Automatic Nail Trimmer to Aid Foot Care of the Elderly

    SBC: ASTER LABS, INC.            Topic: NIA

    DESCRIPTION provided by applicant An estimated in people over age are physically unable to cut their own toenails and of those surveyed admit to difficulty in performing this essential task for routine podiatric health On average shoulder abduction and hip flexion decrease to degrees per decade from age and over a degree per year from age This reduced flexibility combi ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. The Development of a 3D Imaging and Classification System for Exoskeleton Systems

    SBC: INNOVATIVE DESIGN LABS INC            Topic: NIA

    DESCRIPTION provided by applicant Innovative Design Labs IDL in collaboration with the Rehabilitation Institute of Chicago RIC and Ekso Bionics proposes to create a D Imaging and Classification System for Exoskeleton Systems Recent research has found that million Americans require wheelchairs and the number has been increasing annually by an average annual rate of per year Wh ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Novel selective alpha4beta2 nicotinic receptor antagonists for smoking cessation

    SBC: ASSUAGE PHARMACEUTICALS, INC.            Topic: NIDA

    DESCRIPTION provided by applicant Smoking remains the number one avoidable cause of death in the United States and costs the economy tens of billions of dollars every year Current therapies include nicotine replacement with a patch or gum inhibition of the dopamine system with bupropion and partial activation of the neuronal nicotinic acetylcholine receptor nAChR with varenicline Non ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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