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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. A Rapid Method for HLA-typing by Haplotyping

    SBC: GENERATION BIOTECH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Identification of Human Leukocyte Antigens, HLA, for matching of kidney and bone marrow donors and recipients is mandatory for transplantation. Many allele combinations fail to be resolved with current typing methods.

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  2. IMAGING NETWORK FOR BREAST CANCER MASS SCREENING

    SBC: ARTANN LABORATORIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Early detection of breast cancer remains one of the most significant challenges in health care. The tactile breast imager (TBI) is a promising solution that electronically captures the sense of touch to provide a qu

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Validation of a rapid point-of-care breath test for breast cancer

    SBC: MENSSANA RESEARCH INC            Topic: NCI

    DESCRIPTIONprovided by applicantThe clinical problemBreast cancer is the commonest cancer in womenin whom it is second only to lung cancer as a cause of cancer deathMammography is the mainstay of screening for breast cancerthough its value is limited by its large number of false positive and false negative findingsA new solution the problemThe combination of two diagnostic tests with different bio ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Point of Care System for Determination of Bilirubin Capacity in Neonates

    SBC: AVIV BIOMEDICAL INC            Topic: 400

    DESCRIPTION provided by applicant Neonatal hyperbilirubinemia occurs in almost all newborns and may be benign if its progression to extreme hyperbilirubinemia is recognized monitored and prevented or managed in a timely manner Neonatal jaundice carries the risk of neurotoxicity due to the deposition of bilirubin in the central nervous system Most of the bilirubin in plasma is bound to pla ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. A High-Throughput Cell-based Drug Discovery System

    SBC: GENOME DATA SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase II SBIR project is focused at the development of a high-throughput screening method and instrument for drug discovery using miniaturized, cell-based assays. For developing new drugs against complex dise

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Development of protein therapeutic for acute kidney injury

    SBC: TRIM-EDICINE, INC.            Topic: 400

    Project Summary This direct Phase II SBIR proposal focuses on the development of recombinant human MGrhMGa novel tissue repair proteinas a therapeutic candidate targeting injury of renal epithelium to protect against acute kidney injuryAKIAKI is commonly encountered in the hospital and outpatient settings and is associated with a high rate of mortalityCurrentlythere is no effective means for preve ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. THERAPEUTIC USE OF INTER-ALPHA INHIBITOR IN SEPSIS

    SBC: PROTHERA BIOLOGICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of the proposed research is to demonstrate that Inter-alpha serine protease inhibitor proteins (IaIp) are an effective therapy for sepsis. In sepsis, normally high plasma levels of IaIp drop dramatically in

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  8. Development of Novel Fast GPU Monte Carlo and Active Photonics Simulation Software for Predicting PDT Efficacy

    SBC: SIMPHOTEK, INC.            Topic: 102

    DESCRIPTION provided by applicant Photodynamic therapy PDT provides for standalone or intraoperative cancer treatment PDT provides a means to treat superficial and or residual disease while minimizing damage to underlying tissues and does not exhibit cumulative cell toxicities distinguishing it from radiation therapy As compared to radiotherapy treatment planning in PDT is often approa ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Ultra sensitive method for HIV p antigen detection

    SBC: Allied Innovative Systems LLC            Topic: R

    Abstract The ultimate goal of the proposed project is to develop a commercial illumination device detection system kit and original ELISA diagnostic kits for detection of HIV p antigen in human serum or plasma by a photochemical amplification method PAM developed within Phases I and II The methods for identifying HIV infection include HIV antibody tests viral isolation through viral cultur ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. In Situ Autovaccination against Solid Cancers with Intratumoral Hiltonol Poly ICLC A phase II Adaptive Multicenter Clinical Study

    SBC: Oncovir            Topic: 102

    DESCRIPTION provided by applicant Hiltonol poly ICLC is a stabilized dsRNA therapeutic viral mimic or andapos danger signalandapos that activates multiple elements of innate and adaptive immunity It is a standalone immunomodulator but when properly combined with antigen it generates a comprehensive Th weighted immune response best suited for antiviral and antitumor action This project ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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