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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Greener Plastics with High Heat Tolerance for Additive Manufacturing

    SBC: INTELLIGENT OPTICAL SYSTEMS, INC.            Topic: 18NCERP2

    Advances in materials and automation are rapidly reshaping the American manufacturing economy, and must be embraced to sustain a strong manufacturing sector in the United States. Additive manufacturing is possibly the fastest growing example of this trend, growing at an astonishing compound annual growth rate of 25.7%. The plastic materials market for additive manufacturing, valued at $700M in 202 ...

    SBIR Phase II 2019 Environmental Protection Agency
  2. PFAS Analyzer- A fieldable device for the broad-spectrum analysis of PFAS in water, soil, and sediments

    SBC: SEACOAST SCIENCE, INC.            Topic: 18NCERP2

    Polyfluoroalkyl substances (PFAS) are used in food packaging, as coatings for cloth (e.g. Scotchgard), firefighting foams, electronics, and industrial and automotive components. Being perfluorinated species, they are engineered to breakdown slowly (half-life >92 years in water), and thus persist for very long times. Their high water-solubility makes them especially dangerous, and much like perchlo ...

    SBIR Phase II 2019 Environmental Protection Agency
  3. Renewable Bioplastics Production

    SBC: ALTEX TECHNOLOGIES CORPORATION            Topic: 18NCERP2

    Current petroleum-derived-plastics contain additives such as phthalates or bisphenolA that are harmful to human health and the environment. Thus, it’s critical to replace such toxic non-biodegradable plastics with biodegradable bioplastics. To meet bioplastics production need, Altex, and Texas A&M University (TAMU) have teamed up to utilize renewable biomass, such as forest residue, agricultural ...

    SBIR Phase II 2019 Environmental Protection Agency
  4. AI-enabled fully automated retinal image-based biomarkers for mild cognitive impairment and neurodegenerative disorders

    SBC: EYENUK, INC.            Topic: NINDS

    AbstractIn this SBIR projectwe present EyeQuantan AI enabled fully automated tool to compute retinal image based biomarkers for mild cognitive impairment and neurodegenerative disordersThe largegrowingand aging population is likely to lead to a dramatic increase in the number of people at risk for dementia and other cognitive disorderswith more thanmillion people expected to be affected byVascular ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Targeting PDGFs for Potential Treatment of Proliferative Vitreoretinopathy

    SBC: APTITUDE MEDICAL SYSTEMS INC            Topic: NEI

    Abstract SignificanceProliferative vitreoretinopathyPVRis a blinding orphan indication that occurs inof patients receiving rhegmatogenous retinal reattachment surgeryand accounts forof all primary surgical failuresPVR is characterized by migration and proliferation of ectopic cells beneath or on the surface of the retinawhich then assemble into a membranecausing retinal traction and detachmentSinc ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Treatment of Chemotherapy-Induced Peripheral Neuropathy via Genetic Repression of Sodium Channels

    SBC: NAVEGA THERAPEUTICS, INC.            Topic: 102

    Project Summary Abstract The goal of this project is to develop a therapeutic product that relieves chemotherapy induced peripheral neuropathyCIPNin a non permanentnon addictive and long lasting manner to improve the quality of life of cancer patientsCurrently more thanmillion Americans andbillion people worldwide suffer from chronic painVoltage gated sodium channels transmit pain signals in nocic ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Biosensor and Eyedrop Bottle Technologies for Glaucoma Adherence Monitoring

    SBC: Toromedes, Inc            Topic: NEI

    Project SummaryNon adherence with prescribed systemic drugs leads to poor outcomes and increases the cost of healthcareGlaucomathe leading cause of irreversible blindnessaffects more thanmillion people worldwideLowering intraocular pressurethe only proven method of delaying both the development and progression of glaucomais typically done with topical administration of eye dropswhich has notorious ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Development of An Oral,Brain/Eye penetrating, Second Generation TTR Stabilizer for The Treatment of Transthyretin Amyloidoses

    SBC: PROTEGO BIOPHARMA, INC.            Topic: NINDS

    The TTR Amyloidoses (ATTR) are rare, progressive, ultimately fatal diseases that compromise the function of multiple organs, causing a wide range of debilitating clinical symptoms. ATTR is caused by the dissociation of the tetrameric transthyretin (TTR) protein, leading to misfolding and aggregation of the released monomers with toxic oligomer formation and subsequent tissue deposition as physiolo ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a biomimetic small molecule therapeutic for neovascular retinal diseases

    SBC: EyeMedix, Inc.            Topic: NEI

    PROJECT SUMMARY / ABSTRACTRetinal diseases, including age-related macular degeneration (AMD) and diabetic retinopathy (DR) are the leading causes of vision loss and blindness in people over 55 years old. According to the NEI, in 2010 nearly 10 million people in the U.S. suffered from some form of these diseases, whose prevalence is expected to increase to 15 million over 20 years.Recently approved ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Peripherally-Restricted Long-Acting Somatostatin Receptor 4 (LA-SSTR4) Agonists for Pain

    SBC: PEPTIDE LOGIC LLC            Topic: NIDA

    PROJECT SUMMARY ABSTRACT The proposed SBIR Phase II program seeks to select a first in classperipherally restrictedand long acting somatostatin receptorLA SSTRagonist clinical candidate for development as a novel non addictive analgesic able to replace opioids for the treatment of moderate to severe chronic painThe program is based on strong scientific evidence showing that activation of periphera ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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