Award Data

Development of a small UAS compatible Micro IFF transponder including Modes 1,2,3A,C,S , Dual band ADS-B, UAT, Mode 5 and interrogator. All modes include both receive (in) and transmit (out). Size is less than 8 cu inches and weight is under 6 oz with full AIMS 17-1000 compliance, including 500 watt output with diversity. Unit is also low cost and low maintenance. Unit meets full military temperat ...

Project Summary/Abstract: As stated in the Notice of Special Interest announcement, there is a need to populate the recently established MPS database with existing data generated by organ-on-a-chip systems. Having a centralized, public database with data from all available MPS systems will accelerate development and acceptance of the technology ultimately bringing better therapies to patients fast ...

Aging Frailty is a biologically driven geriatric syndrome of multisystem physiological decline that is distinct from normal aging and disproportionately increases vulnerability to adverse clinical outcomes. Frailty has an overall prevalence of 10% of those 65 years and older, and there is growing awareness in the geriatric community to diagnose and treat this condition, as it is not an inevitable ...

Under the subsequent Phase II program, Analysis, Design & Diagnostics, Inc. will work closely with the Office of Naval Research (ONR) and the technical development team from NSWC Panama City to further advance this technology to support mining S&T programs in both shallow and deep water environments. The culmination of this effort will be an end-to-end technology demonstration of the next generati ...

Project SummaryThe goal of this proposal, at the end of the Phase II effort, is to have a service available to academia and industry to screen drugs for Alzheimer’s to predict patient outcomes and determine how potential therapeutics are delivered to the CNS. There are currently few companies able to offer multi-organ evaluation with a recirculating medium utilizing functional readouts, and none ...

A key element for North America’s defense is air domain dominance. Achieving this requires NORAD Battle Control Centers (BCCs) to have a complete understanding of the friendly and foe actors in the airspace, and then form and execute (in real time) both defensive and offensive air battle plans, which are woven into the overall battle plans for land, sea, air, space, and now cyber space doma ...

PROJECT SUMMARY Necrotizing enterocolitis (NEC) is a devastating disease affecting premature infants. Approximately 10% of infants born under 1500 g will develop the disease, and mortality for affected infants is 20-30%. Despite decades of research, the morbidity and mortality of the disease remain generally unchanged. Current treatment and preventive approaches for NEC remain suboptimal, with no ...

Project Summary This project proposes further development of a computational discovery platform shown to quantifiably identify and prioritize both targets and compounds for therapeutic intervention, which will accelerate the development of newer, more effective drugs with fewer side-effects. This platform is based on a novel fusion of two state of the art computational approaches (phenolog mapping ...

Glioblastoma (GBM) is the most lethal form of adult brain cancers with a median survival of andlt;15 months despite aggressive standard chemoradiation. GBM are formed by GBM stem-like cells (GSCs) - a major contributor to tumor recurrence and a natural focus for therapeutic development. There are two main reasons responsible for treatment failure: 1) high intra- and inter-tumor cellular and molecu ...

Under the subsequent Phase II program, Analysis, Design & Diagnostics, Inc. will work closely with the Office of Naval Research (ONR), SEA06-NSW, NUWC Newport and the Integration team from NSWC Panama City to integrate the Sonar Intercept Receiver and CAPs into the SEAL Delivery Vehicle (SDV). The combined system will provide the SDV with an Increased Situational Awareness (ISA) capability for inc ...