Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Product Development of Intensity Modulation for Bolus Electron Conformal Therapy

    SBC: Decimal, LLC            Topic: 102

    Project Summary Abstract ObjectiveThis project aims to elevate electron beam therapyEBTtechnologywhich provides effective radiation treatment for superficial cancersdepthandltcmto that of other external beam radiotherapiesXRTe gx rays and protonsby bringing electron intensity modulation into the clinicChallengeApproximatelyof radiotherapy patientsin USA annuallyreceive EBT for a portion of their t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Bioresorbable Nanoparticles for Visual Detection of Early-Stage Dental Caries

    SBC: GreenMark Biomedical Inc.            Topic: NIDCR

    PROJECT SUMMARY ABSTRACT This project responds to the need identified by NIDCR to develop improved methods to detect and predict progression of dental cariestooth decayto improve human healthWorldwidecaries is the most common chronic disease affecting almost everyoneDental disease is a major cause of economic and social loss and leads to complications including paintooth loss and even deathGeneral ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Automated Intestinal Electrical Stimulation for Diabetes

    SBC: Transtimulation Research Inc.            Topic: 200

    Diabetes affects more thanof Americans and costs over $billion inin USAMedical therapies have limitations in treating diabetic patients with obesity due their common side effects of weight gainBariatric surgery has been proposed for treating diabetic patients with promising outcomesIn this projectwe propose a novel method of intestinal electrical stimulationIESfor treating diabetesPhysiologicallyt ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Infant NeuroLUX: A Novel Non-invasive Therapeutic Device for Neonatal Hypoxic Brain Injury

    SBC: Mitovation, Inc.            Topic: 101

    Neonatal hypoxia ischemia is a known cause of cerebral damage resulting from inadequate blood flow and or oxygen delivery to the infant brain beforeduringor after birthThe occurrence among hospital deliveries isperfull term births with a drastic increase among premature newbornsThe deficit in oxygen delivery to the brain results in extensive damage and severe disabilitiesRestoration of blood flow ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. An Integrated CT-based Image-Guided Neurosurgical System

    SBC: Xoran Technologies LLC            Topic: 102

    An Integrated CT based Image Guided Neurosurgical System In this SBIR Phase IIb proposal Xoran intends to commercialize a compact and affordableyet highlyfunctionalsystem to provide real time image updates and navigation guidance in support of minimally invasive cranial and spinal neurosurgical proceduresThe effort builds on previously developed compact and portable flat panel Computed TomographyC ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a novel small molecule-based approach for accelerated fracture repair in the aging skeleton

    SBC: CAYMAN CHEMICAL COMPANY, INCORPORATED            Topic: NIAMS

    PROJECT SUMMARY ABSTRACT Approximatelymillion fractures occur in the United States each yearaccounting forof all musculoskeletal injuries and leading to well overmillion hospital and physician offices visitsUp toof fractures are recalcitrant and require surgical intervention for proper healingThe weakened bones in the growing geriatric population are contributing to the rising number of cases of t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Repurposing of Pyrvinium Pamoate for Familial Adenomatous Polyposis (FAP)

    SBC: Stemsynergy Therapeutic            Topic: 102

    ABSTRACT Individuals with the rareinherited disorder Familial Adenomatous PolyposisFAPdevelop thousands of precancerous polyps at an early age and ultimately develop colorectal cancerCRCThe current standard of care for FAP is colectomyHoweverunavoidable side effects of colectomy are debilitatingFurthermorecolectomy does not prevent subsequent development of extra colonic intestinal tumorsthe main ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Articulating Video Stylet for Improved Intubation Success Rates

    SBC: BRIO DEVICE, LLC            Topic: NHLBI

    Project SummaryMore thanmillion intubations are performed in the US every year and may carry a high rate of procedure related and disease related complicationsThe higher incidence of difficult intubation in children is due to a more anterior larynx and presence of congenital syndromes resulting insuffering complications during and related to airway managementDifficult intubations in pediatric pati ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Dual Plane 3D Compton Scattering Imager with Pixelated CZT Detectors for 1-10MeV Gamma Ray

    SBC: H3D            Topic: None

    Phase I has proven that the current setup achieves better than 8mm spatial resolution for 2.2MeV prompt gammas. However, 1mm spatial resolution presents a significant challenge for the current setup due in part to limited timing resolution and count rate. A new analog ASIC will be developed to replace the current analog ASIC that will have better timing resolution and deliver higher count rates. I ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  10. An integrated electrical impedance myography platform for neuromuscular disease classification and diagnosis

    SBC: Myolex Inc            Topic: 103

    Project SummaryImproved methods for the bedside diagnosis and evaluation of neuromuscular disorders are neededOne technology that is finding increasing use for this purpose is electrical impedance myographyEIMIn EIMa very weakhigh frequency electrical current is passed through a muscle of interest and the resulting surface voltages are measuredDisease associated alterations in the composition and ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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