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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Product Development of Intensity Modulation for Bolus Electron Conformal Therapy
SBC: Decimal, LLC Topic: 102Project Summary/Abstract Objective: This project aims to elevate electron beam therapy (EBT) technology, which provides effective radiation treatment for superficial cancers (depthandlt;6 cm), to that of other external beam radiotherapies (XRT), e.g. x-rays and protons, by bringing electron intensity modulation into the clinic. Challenge: Approximately 10% of radiotherapy patients (173,000 in U ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Bioresorbable Nanoparticles for Visual Detection of Early-Stage Dental Caries
SBC: GreenMark Biomedical Inc. Topic: NIDCRPROJECT SUMMARY/ABSTRACT This project responds to the need identified by NIDCR to develop improved methods to detect and predict progression of dental caries (tooth decay) to improve human health. Worldwide, caries is the most common chronic disease affecting almost everyone. Dental disease is a major cause of economic and social loss and leads to complications including pain, tooth loss and even ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Automated Intestinal Electrical Stimulation for Diabetes
SBC: TRANSTIMULATION RESEARCH INC Topic: 200Diabetes affects more than 9% of Americans and costs over $300 billion in 2017 in USA. Medical therapies have limitations in treating diabetic patients with obesity due their common side effects of weight gain. Bariatric surgery has been proposed for treating diabetic patients with promising outcomes. In this project, we propose a novel method of intestinal electrical stimulation (IES) for treatin ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Infant NeuroLUX: A Novel Non-invasive Therapeutic Device for Neonatal Hypoxic Brain Injury
SBC: Mitovation, Inc. Topic: 101Neonatal hypoxia/ischemia is a known cause of cerebral damage resulting from inadequate blood flow and/or oxygen delivery to the infant brain before, during, or after birth. The occurrence among hospital deliveries is ~2-4 per 1000 full-term births with a drastic increase among premature newborns. The deficit in oxygen delivery to the brain results in extensive damage and severe disabilities. Rest ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
An Integrated CT-based Image-Guided Neurosurgical System
SBC: Xoran Technologies LLC Topic: 102An Integrated CT-based Image-Guided Neurosurgical System In this SBIR Phase IIb proposal Xoran intends to commercialize a compact and affordable, yet highly- functional, system to provide real time image updates and navigation guidance in support of minimally invasive cranial and spinal neurosurgical procedures. The effort builds on previously developed compact and portable flat-panel Computed Tom ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Development of a novel small molecule-based approach for accelerated fracture repair in the aging skeleton
SBC: CAYMAN CHEMICAL COMPANY, INCORPORATED Topic: NIAMSPROJECT SUMMARY/ABSTRACT Approximately 6.3 million fractures occur in the United States each year, accounting for 16% of all musculoskeletal injuries and leading to well over 10 million hospital and physician offices visits. Up to 10% of fractures are recalcitrant and require surgical intervention for proper healing. The weakened bones in the growing geriatric population are contributing to the ri ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Repurposing of Pyrvinium Pamoate for Familial Adenomatous Polyposis (FAP)
SBC: Stemsynergy Therapeutic Topic: 102ABSTRACT Individuals with the rare, inherited disorder Familial Adenomatous Polyposis (FAP) develop thousands of precancerous polyps at an early age and ultimately develop colorectal cancer (CRC). The current standard of care for FAP is colectomy. However, unavoidable side-effects of colectomy are debilitating. Furthermore, colectomy does not prevent subsequent development of extra-colonic intesti ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Articulating Video Stylet for Improved Intubation Success Rates
SBC: BRIO DEVICE, LLC Topic: NHLBIProject SummaryMore than 20 million intubations are performed in the US every year and may carry a high rate of procedure-related and disease-related complications. The higher incidence of difficult intubation in children is due to a more anterior larynx and presence of congenital syndromes resulting in 20% suffering complications during and related to airway management. Difficult intubations in p ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Dual Plane 3D Compton Scattering Imager with Pixelated CZT Detectors for 1-10MeV Gamma Ray
SBC: H3D INC Topic: NonePhase I has proven that the current setup achieves better than 8mm spatial resolution for 2.2MeV prompt gammas. However, 1mm spatial resolution presents a significant challenge for the current setup due in part to limited timing resolution and count rate. A new analog ASIC will be developed to replace the current analog ASIC that will have better timing resolution and deliver higher count rates. I ...
SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology -
Targeting glioblastoma stem-like cells with custom-designed viral vectors
SBC: Lacerta Therapeutics, Inc. Topic: 102Glioblastoma (GBM) is the most lethal form of adult brain cancers with a median survival of andlt;15 months despite aggressive standard chemoradiation. GBM are formed by GBM stem-like cells (GSCs) - a major contributor to tumor recurrence and a natural focus for therapeutic development. There are two main reasons responsible for treatment failure: 1) high intra- and inter-tumor cellular and molecu ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health