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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Improved Microcalorimeter Detectors for X-Ray Chemical Shift Mapping

    SBC: STAR CRYOELECTRONICS, LLC            Topic: N/A

    X-ray fluorescence spectroscopy is a widely used and extremely sensitive analytical technique for qualitative as well as quantitative chemical analysis. Superconducting Transition Edge Sensor (TES) microcalorimeter detectors have now been developed that achieve an energy resolution of 2 eV (full width at half maximum) for 1.5 keV X-rays, which is sufficient to enable the measurement of the small s ...

    SBIR Phase I 2012 Department of CommerceNational Institute of Standards and Technology
  2. Reduction of Dietary Oxalate

    SBC: CAPTOZYME LLC            Topic: NCCAM

    DESCRIPTION (provided by applicant): Kidney stones are a common and painful human health care problem worldwide. Of all stones developed approximately 75% are composed of calcium oxalate. Urinary oxalate is regarded as a driving force for calcium oxalate stone formation, and absorption of dietary oxalate contributes to 10-70% of urinary oxalate. In fact, roughly 2.4 million Americans (0.75% of the ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  3. Development of Wnt Pathway Inhibitors for Colorectal Cancer

    SBC: Stemsynergy Therapeutic            Topic: NCI

    DESCRIPTION (provided by applicant): StemSynergy Therapeutics Inc. (SSTI) is a biopharmaceutical company focused on the discovery, development, and commercialization of drugs that target pathways fundamental to stem cells and cancer stem cells. The WorldHealth Organization estimates that over 12 million cases of cancer were diagnosed in 2007 and that nearly 8 million cancer patients will die of t ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  4. Quick-Set Material-Phase II

    SBC: PRIMUS CONSULTING            Topic: NIDCR

    DESCRIPTION (provided by applicant): Quick-Set Material- Phase II Quick-Set material is proposed for vital pulp therapy and for non-vital endodontic use to make the clinical procedures shorter and more consistent, of benefit to the patient and clinician,and enhance the probability for a positive outcome. The new material should promote regeneration of the periodontal ligament and cemental tissues ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  5. A perfluorocarbon-based culture device for beta cell biology applications (Phase

    SBC: Ophysio Inc.            Topic: NIDDK

    ABSTRACT Conventional culture vessels are not designed for physiological oxygen delivery. Both hyperoxia and hypoxia - commonly observed when culturing cells and tissues in regular plasticware- have been linked to reduced cellular function and death. An adequate means to provide oxygenation is also critical for stem cell applications in which the differentiation outcome is dependent on oxygen ten ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Computer Based Screening for Diabetic Retinopathy

    SBC: VisionQuest Biomedical Inc            Topic: NEI

    DESCRIPTION (provided by applicant): The objective of this Phase II competitive renewal project is to implement a clinical study to collect data to validate EyeStar(tm), a software system as the basis for comprehensive telescreening for all stages of diabetic retinopathy (DR). According to the CDC, approximately 80 million people in the U.S. have some form of eye disease, including 20 million dia ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Safety and Efficacy of Single-use Cliradex Pads for Ocular Mites

    SBC: BIOTISSUE HOLDINGS INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Demodex mites are microscopic ectoparasites that commonly infest the pilosebaceous unit of the skin. Uncontrolled overgrowth of mites has been implicated in causing papulopustular lesions in the skin, rosacea in the face, and blepharitis in the eye. Blepharitis (lid margin inflammation) associated with mite-harboring cylindrical dandruff in eyelashes is one of ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Amniotic Membrane versus Pericardium in Reducing Glaucoma Drainage Tube Exposure

    SBC: BIOTISSUE HOLDINGS INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Glaucoma drainage devices (GDDs) have widely been used in the treatment of high-risk refractory glaucoma. To avoid tube exposure, which may lead to serious eye infection, the implanted GDD tube must be covered by apatch graft traditionally made of either donor sclera or pericardium. However, these patch grafts still carry a high rate of progressive thinning ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Automated Eye Disease Screening System

    SBC: VisionQuest Biomedical Inc            Topic: NEI

    DESCRIPTION (provided by applicant): This proposed project is motivated by the fact that comprehensive, broad-scale screening for eye diseases such as age-related macular degeneration (AMD), glaucoma, and diabetic retinopathy (DR), including advanced stages, is economically prohibitive without the introduction of computer-assisted diagnosis of retinal images. According to the CDC approximately 80 ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  10. ABLE Kids II- Advanced Biofidelic Lower Extremity Kids Prosthesis II

    SBC: ORTHOCARE INNOVATIONS LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): The Advanced Biofidelic Lower Extremity Kids prosthesis (ABLE Kids) project will advance the state-of-the-art of pediatric prosthesis systems by advancing the demonstrably successful Phase I device and refining it intoan ultracompact and lightweight form factor suitable for pediatric use. Through the support of the Shriner's Hospitals in Salt Lake City, U ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
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