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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A computational platform to improve the prioritization of drugs and target genes for therapeutic intervention

    SBC: Genetic Networks, LLC            Topic: 100

    Project Summary This project proposes further development of a computational discovery platform shown to quantifiably identify and prioritize both targets and compounds for therapeutic intervention, which will accelerate the development of newer, more effective drugs with fewer side-effects. This platform is based on a novel fusion of two state of the art computational approaches (phenolog mapping ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. ADAMANT: Adaptive Manipulation for Tasks

    SBC: Traclabs Inc.            Topic: Z5

    Robots will play an important role in NASA#39;s upcoming missions to the Moon and beyond.nbsp; They will need to manipulate their environment in complex and useful ways - carrying objects, using tools, and assisting crew.nbsp; NASArsquo;s humanoid robots have highly dexterous end-effectors, but developing software to fully utilize such hands remains a challenging task.nbsp; Grasping strategies are ...

    SBIR Phase II 2019 National Aeronautics and Space Administration
  3. ADAPTIVE COMPUTATIONAL METHOD FOR FLUID-STRUCTURE INTERACTION IN INTERNAL FLOWS

    SBC: Computational Mechan            Topic: N/A

    SUPER ACCURATE ADAPTIVE COMPUTATIONAL SCHEMES FOR THE ANALYSIS OF FLUID STRUCTURE INTERACTION AND COMPLEX THREE-DIMENSIONAL INTERNAL FLOWS ARE TO BE DEVELOPED. NEW PETROV-GALERKIN FINITE ELEMENT METHODS FOR SOLVING THE NAVIER-STOKES EQUATIONS. COUPLED WITH THE EQUATIONS OF MOTION OF ELASTIC DUCTS AND MANIFOLDS, ARE TO BE DEVELOPED AND USED TO SIMULATE FLOWS IN AEROSPACE PROPULSION SYSTEMS (SUCH AS ...

    SBIR Phase II 1987 National Aeronautics and Space Administration
  4. Advanced development of a novel nanoparticle conjugate vaccine for Salmonella Paratyphi A

    SBC: KJ BIOSCIENCES LLC            Topic: NIAID

    Salmonella Paratyphi ASParatyphi Ais a major cause of life threatening enteric feverThere is no vaccine available against this pathogenIn the SBIR phase I studieswe have successfully demonstrated the technical feasibility of a novel nanoparticle conjugate vaccine candidate for SParatyphi AIt is based on O polysaccharideOPSantigen conjugated to a novel and highly advantageous nanoparticle protein c ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. ADVANCED HELIUM NAGNETOMETERS FOR SPACE APPLICATIONS

    SBC: POLATOMIC, INC.            Topic: N/A

    THE GOAL OF PHASE I IS DEVELOPMENT OF AN ADVANCED OPTICALLY PUMPED HELIUM MAGNETOMETER CONCEPT. THIS INSTRUMENT WILL MEASURE MAGNETIC FIELDS IN THE 1 TO 10-8 GAUSS RANGE WITH ORDER OF MAGNITUDE IMPROVEMENTS IN SENSITIVITY AND ABSOLUTE ACCURACY OVER EXISTING MAGNETOMETERS. OPTICALLY PUMPED HELIUM ISOTOPES CAN BE OPTICALLY PUMPED AND USED AS MAGNETOMETERS IN THE FOLLOWING THREE MODES: (1) VECTOR MOD ...

    SBIR Phase II 1987 National Aeronautics and Space Administration
  6. Advanced Structural Health Monitoring

    SBC: TEXAS RESEARCH INSTITUTE , AUSTIN, INC.            Topic: T12

    Frequency selective surfaces (FSSs) are periodic arrays of conductive elements/patches that cause a particular reflection response when illuminated with high frequency electromagnetic energy. nbsp;These arrays arenbsp;used for high frequency filters and in antenna applications.nbsp; We propose to use FSSs as multi-functional sensors. nbsp;FSS sensors are unpowered, low-profile (thin), wireless and ...

    STTR Phase II 2019 National Aeronautics and Space Administration
  7. Air Barrier System for the Prevention of Prosthesis-related Infections

    SBC: NIMBIC SYSTEMS, INC.            Topic: 300

    DESCRIPTIONprovided by applicantThis project is an evaluation of a novel devicethe Air Barrier SystemABSto reduce the risk of prosthesisrelated surgical site infection in a multi center clinical trialThe ABS shields surgical incisions intra operatively by creating a field of high purity air surrounding an incision that prevents airborne microorganisms from entering the incisionPreliminary findings ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. A METHOD FOR OPTIMIZING ATMOSPHERES FOR SPACE LIFE SUPPORT SYSTEMS

    SBC: Phytoresource Research Inc            Topic: N/A

    IT IS GENERALLY ACCEPTED THAT HIGHER PLANTS WILL SERVE AS IMPORTANT COMPONENTS OF ENVIRONMENTAL CONDITIONING AND FOOD PRODUCTION SYSTEMS FOR FUTURE SPACE OR PLANETARY SURFACE HABITATS. BECAUSE OF STRUCTURAL CONSIDERATIONS IT IS LIKELY THAT ATMOSPHERIC COMPOSITION AND PRESSURE WILL BE RADICALLY DIFFERENT. IN DEFINING GROWTH SYSTEMS FOR ALTEREDATMOSPHERES WE MUST UNDERSTAND HOW PLANTS OPERATE IN GEN ...

    SBIR Phase II 1987 National Aeronautics and Space Administration
  9. An integrated electrical impedance myography platform for neuromuscular disease classification and diagnosis

    SBC: MYOLEX, INC.            Topic: 103

    Project SummaryImproved methods for the bedside diagnosis and evaluation of neuromuscular disorders are needed. One technology that is finding increasing use for this purpose is electrical impedance myography (EIM). In EIM, a very weak, high frequency electrical current is passed through a muscle of interest and the resulting surface voltages are measured. Disease associated alterations in the com ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A Phase 2b Clinical Trial to Study the Efficacy of Longeveron Mesenchymal Stem Cells (LMSCs) to Treat Aging Frailty

    SBC: Longeveron LLC            Topic: NIA

    Aging Frailty is a biologically driven geriatric syndrome of multisystem physiological decline that is distinct from normal aging and disproportionately increases vulnerability to adverse clinical outcomes. Frailty has an overall prevalence of 10% of those 65 years and older, and there is growing awareness in the geriatric community to diagnose and treat this condition, as it is not an inevitable ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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