Award Data

Systems & Processes Engineering Corporation (SPEC) proposes to develop a highly sensitive point pathogen detection system based on Force Amplified Biosensor (FAB) technology. Similar to Atomic Force Microscopy (AFM). FAB employs a greatly simplified AFM configuration to measure intermolecular interactions. By employing immobilized antibodies and very small, well characterized, magnetic beads, ex ...

Recent events in the Middle East have focused worldwide attention toward the escalating threat of chemical and biological warfare. Naval Aviators exposed to potential CBW threats need a means to rehydrate themselves in the cockpit. Numerous studies have shown that proper hydration is essential for maximum physical and mental performance. Texas Research Institute Austin, Inc. (TRI/Austin) will te ...

Protective clothing technology is a key element in chemical and biological defense, There is a need for a spray-on coating, similar to 3M's Scotch Gard1 which will enhance the barrier properties of standard protective clothing and aid in decontamination. Two approaches have been developed for fabric protection: (1) high surface free energy, low molecular weight resins which are chemically bonded t ...

methyst Research Inc. will design, fabricate and test a high uniformity, large area, low noise infrared trap-detector detector for the 1- 4.5 μm wavelength range. This state of the art detector will have a large area (e.g., 1-1.8 cm diameter active area) with a spatial variability of internal quantum efficiency of less than 0.1 % between 1 μm and 4.5 μm. In addition, the internal quantum effici ...

Burkholderia pseudomallei and Burkholderia mallei are highly pathogenic Gram - negative bacteria and the causative agents of melioidosis and glanders, respectively. These infections, which occur in humans and other animals, are endemic is wide regions of the developing world. This Phase II SBIR project will build on the success of our Phase I work, which established methods for generating monoclon ...

Modern Model-Based Enterprise / Engineering (MBE) systems rely on freeform surfaces built as complex combinations of geometric primitives to define engineered objects. Unfortunately, the intersection of freeform surfaces in MBE applications results in highly approximated solutions, degrading models that cost billions annually by US industry to fix. Current technology limits the abilities of users ...

In this Phase I SBIR proposal, SandBox Semiconductor™ proposes to develop an Advanced Manufacturing and Material Measurements software tool called Weave ™ for accelerating and automating SEM image analysis for the semiconductor industry. During the development of a new manufacturing process line for a semiconductor device, tens of thousands of scanning electron microscopy (SEM) images are take ...

This project will develop a new scientific instrument optimized for the advanced characterization of near-infrared fluorescent nanoparticles that can exist as left- or right-handed structures (enantiomers). Single-walled carbon nanotubes (SWCNTs) are the leading current example of such nanomaterials. Applied NanoFluorescence, LLC (ANF) proposes a novel multi-mode chiroptical spectrometer that can ...

Highly pathogenic alphaviruses like VEEV/EEV/WWEEV cause encephalitis in humans and equids. These infections are endemic in wide regions of the developing world. Translational research regarding these pathogens is focused on developing new strategies to detect, treat and ideally protect humans and animals from these infections. Gene-encoded antibodies against alphavirus E1/E2 surface proteins will ...

For standoff chemical identification applications, the longwave infrared has several key lines for spectral discrimination. Unfortunately, most hyperspectral systems are quite large and fragile, making them unwieldy. Nanohmics proposes to demonstrate a chip-scale longwave infrared hyperspectral imaging technology. The weight and packaging volume will be dominated by the fore-optics instead of the ...