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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Gap-Free Model-Based Engineering for Manufacturing and Analysis: Digital Thread without Translation

    SBC: Nvariate, Inc.            Topic: None

    Modern Model-Based Enterprise / Engineering (MBE) systems rely on freeform surfaces built as complex combinations of geometric primitives to define engineered objects. Unfortunately, the intersection of freeform surfaces in MBE applications results in highly approximated solutions, degrading models that cost billions annually by US industry to fix. Current technology limits the abilities of users ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Advanced Manufacturing and Material Measurements Software Tool Weave ™ for the Acceleration and Automation of SEM Image Analysis in the Semiconductor Industry

    SBC: Sandbox Semiconductor Incorporated            Topic: None

    In this Phase I SBIR proposal, SandBox Semiconductor™ proposes to develop an Advanced Manufacturing and Material Measurements software tool called Weave ™ for accelerating and automating SEM image analysis for the semiconductor industry. During the development of a new manufacturing process line for a semiconductor device, tens of thousands of scanning electron microscopy (SEM) images are take ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  3. Rapid, Accurate Point-of-Care Test for Gonorrhea and Determination of Antimicrobial Susceptibility

    SBC: AI BIOSCIENCES, INC.            Topic: NIAID

    Antimicrobial resistant gonorrheacaused by Neisseria gonorrhoeaeNGhas become an urgent threat for global public healthThe goal of this project is to develop a one hour point of care diagnosticPOCtest capable of identifying NGand determining the infecting strain s susceptibility to antibioticsAI Biosciences plans to achieve this goal by expanding the capability of its POC system being developed for ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Development of Aptamer Affinity Reagents to Immune Targets in Non-human Disease Models

    SBC: BASE PAIR BIOTECHNOLOGIES INC            Topic: NIAID

    This goal of this program is to address the limited availability of reagentsantibodiesproteinsligandsfor the identification and discrimination of immune cells and the characterization of immune responses in nonmammalian models and mammalian models for which immunologic reagents are limitede gguinea pigferretcotton ratFor examplethe progression of disease that follows infection of guinea pigs with ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Fluorescent Qdot Immunochromatographic Test Strips for Influenza A B and Group A Strep

    SBC: NANOHMICS INC            Topic: ODCDC

    Nanohmics proposes to develop ultrasensitive and specific antibody based sandwich lateral flowLFtest strips for influenza A and B hemagglutinins and neuraminidasesas well as Group A StreptococcusSpyogenesfrom throat and nasal swabs or saliva samplesVery good LF test strips are already marketed for these highly important disease analytesBut to improve detectionNanohmics will incorporate fluorescent ...

    SBIR Phase I 2019 Department of Health and Human ServicesCenters for Disease Control and Prevention
  6. Multifunctional Cold Chain Container for Unmanned Aerial Vehicle Transport

    SBC: BLOODSTONE DIVISION LLC            Topic: ODCDC

    Development of an agile device that can deliver supplies to and from remote locations during public health emergenciesIn the context of emergency public health responsedrones could be extremely useful for transporting necessary supplies to remote or inaccessible locationsSupplies might include dry goodsbut would certainly include clinical specimensreagent kitsvaccines and other perishable goodsThe ...

    SBIR Phase I 2019 Department of Health and Human ServicesCenters for Disease Control and Prevention
  7. NCATS SBIR 2019 PHASE I PROPOSALS TOPIC 018 ENTITLED NON-PDMS BIOCOMPATIBLE ALTERNATIVES FOR ORGANS-ON-CHIPS

    SBC: LYNNTECH INC.            Topic: NIDA

    Microfluidic organ on a chipOOCsystems offer a distinct advantage over existing in vitro systems through incorporation of micro architecture to a cultured cell line sthat structurely and mechanically mimic more closely in vivo physiological conditions in an in vitro constructThese OOC devices are typically constructed from polydimethylsiloxanePDMShoweverPDMS has several drawbacks that can impact t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. TOPIC 393: BREATH TEST FOR BIOMARKERS OF RADIATION EXPOSURE

    SBC: MENSSANA RESEARCH INC            Topic: NCI

    The problemPatients receiving therapeutic radiation are at risk of adverse toxic effectsThese adverse events are usually unpredictable and may result in severe morbidity or mortalityExampleA third or more of patients receiving chest radiation for cancers of lung may develop life threatening acute radiation pneumonitisThe clinical needThere is a clinical need for an objective test to estimate the b ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. A Large-Scale Microfluidics Imaging Platform for High-Throughput Toxicity Testing using Canine Intestinal Organoids

    SBC: VIVOVERSE, INC.            Topic: NIEHS

    Project SummaryCurrentlytoxicology studies require a large number of animal testing to identify better and safer drug candidatesIn an attempt to reduce the use of large animals in pharmaceutical industrythere is a need to bridge the gap between the conventional in vitro cell based assay and the non human animal studiesRecentlythreedimensional models are gaining momentum and replacing conventionalD ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Screening Device for Autism Spectrum Disorders using High Stimulation Rate ABR with Continuous Loop Averaging Deconvolution

    SBC: INTELLIGENT HEARING SYSTEMS CORP            Topic: NIDCD

    The purpose of this proposal is to develop an automated Auditory Brainstem ResponseABRbased neurological screening device and software module that will enhance the early detection of autism and other neurological conditionsAutism Spectrum DisordersASDhave an incidence rate ofBased onmillion births in the United States innew cases of ASD will be diagnosed from that birth cohort aloneThe practice of ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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