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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Next Generation Tools for Onsite Monitoring and Treatment of Drug of Abuse-Dependent Persons
SBC: SensoDX II, LLC Topic: NIDAAbstract Opioid abuse disorder (OAD) affects 2.1 million of Americans annually resulting in overdoses numbering in the tens of thousands and skyrocketing rates of mortality. In addition to its enormous social impact, OAD carries a multi-billion-dollar price tag that includes $78.5 billion, specifically for health care and other costs related to prescription opioid abuse and misuse. Although effect ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Long-term therapeutic effects of synthetic bryostatin-1 in advanced AD without memantine
SBC: SYNAPTOGENIX, INC. Topic: RProgram Director/Principal Investigator (Last, First, Middle): Miao-Kun Sun Project Summary/Abstract The importance of memory impairment and dementias, including Alzheimer’s disease (AD), as a global priority has been well recognized. Many compounds that target AD pathologies have been developed preclinically but have failed in clinical trials, mostly for the lack of therapeutic efficacies.Neuro ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Rapid and Effective Localized Neurovascular Cooling Using the Khione Insulative Catheter
SBC: Tom L Merrill Topic: 101Project Summary Stroke is the 5th leading cause of death and number one cause of adult disability in the United States. The primary goal of acute ischemic stroke (AIS) treatment is quickly restoring blood perfusion. However, studies have shown that this return of blood flow, while necessary, can also cause damage to local tissue leading to poor patient outcomes. Therapeutic hypothermia (TH) has be ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Graphene-based Nanosensor Device for Rapid, Onsite Detection of Total Lead in Tap Water
SBC: NANOAFFIX SCIENCE LLC Topic: NIEHSPROJECT SUMMARY Detrimental health impacts of lead are largely attributed to long-term exposures to undetected lead, which are particularly troublesome and problematic because of the neurological damage to children, a situation that should not be tolerated by an advanced society like the U.S. The Flint Water Crisis and many other water catastrophes could have been avoided if early warning can be m ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Product Development of Intensity Modulation for Bolus Electron Conformal Therapy
SBC: Decimal, LLC Topic: 102Project Summary/Abstract Objective: This project aims to elevate electron beam therapy (EBT) technology, which provides effective radiation treatment for superficial cancers (depthandlt;6 cm), to that of other external beam radiotherapies (XRT), e.g. x-rays and protons, by bringing electron intensity modulation into the clinic. Challenge: Approximately 10% of radiotherapy patients (173,000 in U ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Improving Repair of Female Congenital and Reproductive Anomalies
SBC: Biotex, Inc. Topic: NICHDProject Summary The overall goal of this SBIR proposal is to develop a novel vaginal stent for use in pediatric and adult populations. There are many girls and women born with congenital gynecologic abnormalities requiring surgical reconstruction of their vaginal cavities. There are also women who have very shortened or scarred vaginas after pelvic surgery or radiation treatment for cancer. Vagina ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Performance Evaluation of a non-Degradable Synthetic Device for Chondral and Osteochondral Defects of the Knee
SBC: Hydro-Gen LLC Topic: NIAMSInjury to joints can lead to painful defects in articular cartilage and the underlying bone, which adversely affect the function and biological health of the entire joint. Current solutions for cartilage (chondral) and cartilage-and- bone (osteochondral) defects, are unreliable, are technically challenging, and often require multiple procedures. A surgeon-engineer-biologist team at Hospital for Sp ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
3D-Printed Superhydrophobic-Tipped Optical Fiber for Targeted Periodontal Photodynamic Therapy
SBC: SINGLETO2 THERAPEUTICS LLC Topic: NIDCREradication of bacteria located in periodontal pockets presents a daunting challenge to dentists and oral care professionals. The problem is significant; severe periodontitis is the 6th most prevalent disease worldwide with over 743 million people affected. The global cost of lost productivity from severe periodontitis is estimated to be $54 billion USD/year. Antibiotics with scaling and root plan ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Automated Intestinal Electrical Stimulation for Diabetes
SBC: TRANSTIMULATION RESEARCH INC Topic: 200Diabetes affects more than 9% of Americans and costs over $300 billion in 2017 in USA. Medical therapies have limitations in treating diabetic patients with obesity due their common side effects of weight gain. Bariatric surgery has been proposed for treating diabetic patients with promising outcomes. In this project, we propose a novel method of intestinal electrical stimulation (IES) for treatin ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Accelerating Functional Maturation of Human Neurons for High-Throughput Screening
SBC: BrainXell, Inc Topic: 44Project Summary/AbstractNeurological and psychiatric disorders, including drug abuse and addiction, exert a devastating personal and economic toll on patients, families, caregivers, and society. This is in part due to our failure in developing effective medications, which in turn is due to the use of drug discovery platforms that are often not relevant to target diseases. The recent development of ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health