Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Next Generation Tools for Onsite Monitoring and Treatment of Drug of Abuse-Dependent Persons

    SBC: SensoDX II, LLC            Topic: NIDA

    Abstract Opioid abuse disorderOADaffectsmillion of Americans annually resulting in overdoses numbering in the tens of thousands and skyrocketing rates of mortalityIn addition to its enormous social impactOAD carries a multi billion dollar price tag that includes $billionspecifically for health care and other costs related to prescription opioid abuse and misuseAlthough effective interventions exis ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Long-term therapeutic effects of synthetic bryostatin-1 in advanced AD without memantine

    SBC: Neurotrope Bioscience, Inc.            Topic: R

    Program Director Principal InvestigatorLastFirstMiddleMiao Kun Sun Project Summary Abstract The importance of memory impairment and dementiasincluding Alzheimer s diseaseADas a global priority has been well recognizedMany compounds that target AD pathologies have been developed preclinically but have failed in clinical trialsmostly for the lack of therapeutic efficaciesNeurotrope Bioscience Incis ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Rapid and Effective Localized Neurovascular Cooling Using the Khione Insulative Catheter

    SBC: Tom L Merrill            Topic: 101

    Project Summary Stroke is theth leading cause of death and number one cause of adult disability in the United StatesThe primary goal of acute ischemic strokeAIStreatment is quickly restoring blood perfusionHoweverstudies have shown that this return of blood flowwhile necessarycan also cause damage to local tissue leading to poor patient outcomesTherapeutic hypothermiaTHhas been shown to be a robus ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Graphene-based Nanosensor Device for Rapid, Onsite Detection of Total Lead in Tap Water

    SBC: NANOAFFIX SCIENCE LLC            Topic: NIEHS

    PROJECT SUMMARY Detrimental health impacts of lead are largely attributed to long term exposures to undetected leadwhich are particularly troublesome and problematic because of the neurological damage to childrena situation that should not be tolerated by an advanced society like the U SThe Flint Water Crisis and many other water catastrophes could have been avoided if early warning can be made po ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Product Development of Intensity Modulation for Bolus Electron Conformal Therapy

    SBC: Decimal, LLC            Topic: 102

    Project Summary Abstract ObjectiveThis project aims to elevate electron beam therapyEBTtechnologywhich provides effective radiation treatment for superficial cancersdepthandltcmto that of other external beam radiotherapiesXRTe gx rays and protonsby bringing electron intensity modulation into the clinicChallengeApproximatelyof radiotherapy patientsin USA annuallyreceive EBT for a portion of their t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Improving Repair of Female Congenital and Reproductive Anomalies

    SBC: Biotex, Inc.            Topic: NICHD

    Project Summary The overall goal of this SBIR proposal is to develop a novel vaginal stent for use in pediatric and adult populationsThere are many girls and women born with congenital gynecologic abnormalities requiring surgical reconstruction of their vaginal cavitiesThere are also women who have very shortened or scarred vaginas after pelvic surgery or radiation treatment for cancerVaginal sten ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Performance Evaluation of a non-Degradable Synthetic Device for Chondral and Osteochondral Defects of the Knee

    SBC: Hydro-Gen LLC            Topic: NIAMS

    Injury to joints can lead to painful defects in articular cartilage and the underlying bonewhich adversely affect the function and biological health of the entire jointCurrent solutions for cartilagechondraland cartilage andboneosteochondraldefectsare unreliableare technically challengingand often require multiple proceduresA surgeon engineer biologist team at Hospital for Special SurgeryHSSdedica ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. 3D-Printed Superhydrophobic-Tipped Optical Fiber for Targeted Periodontal Photodynamic Therapy

    SBC: SingletO2 Therapeutics LLC            Topic: NIDCR

    Project Summary Abstract Eradication of bacteria located in periodontal pockets presents a daunting challenge to dentists and oral care professionalsThe problem is significantsevere periodontitis is theth most prevalent disease worldwide with overmillion people affectedThe global cost of lost productivity from severe periodontitis is estimated to be $billion USD yearAntibiotics with scaling and ro ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Automated Intestinal Electrical Stimulation for Diabetes

    SBC: Transtimulation Research Inc.            Topic: 200

    Diabetes affects more thanof Americans and costs over $billion inin USAMedical therapies have limitations in treating diabetic patients with obesity due their common side effects of weight gainBariatric surgery has been proposed for treating diabetic patients with promising outcomesIn this projectwe propose a novel method of intestinal electrical stimulationIESfor treating diabetesPhysiologicallyt ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Accelerating Functional Maturation of Human Neurons for High-Throughput Screening

    SBC: BrainXell, Inc            Topic: 44

    Project Summary AbstractNeurological and psychiatric disordersincluding drug abuse and addictionexert a devastating personal and economic toll on patientsfamiliescaregiversand societyThis is in part due to our failure in developing effective medicationswhich in turn is due to the use of drug discovery platforms that are often not relevant to target diseasesThe recent development of induced pluripo ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government