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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Better High-level Disinfectant for Endoscopes and Other Medical Equipments/Devi

    SBC: INNOVATIVE RESEARCH SOLUTIONS INC            Topic: NIDDK

    DESCRIPTION (provided by applicant): We are developing a novel two-part cold high-level disinfecting (HLD)/sterilization technology that will be ready to work by mixing in water, just minutes before use. Both components separately are relatively inactive,non-toxic and stable chemicals that have good shelf life, and easy handling restrictions compared to the currently used HLD products, ensuring th ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  2. A Biodégradable and Biomimetic Xerogel for Periodontal Bone Regeneration

    SBC: INNOVATIVE RESEARCH SOLUTIONS INC            Topic: NIDCR

    DESCRIPTION provided by applicant Periodontal bone regeneration requires attention to a the need of a physical barrier to restrict the entry formation of fibro epithelial tissue b he cause of bone loss that is due to hostandapos s inflammatory response to pathological cause and not due to the causative pathogen directly so along with bone regeneration strategies the process also equally ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. ABLE Kids II- Advanced Biofidelic Lower Extremity Kids Prosthesis II

    SBC: ORTHOCARE INNOVATIONS LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): The Advanced Biofidelic Lower Extremity Kids prosthesis (ABLE Kids) project will advance the state-of-the-art of pediatric prosthesis systems by advancing the demonstrably successful Phase I device and refining it intoan ultracompact and lightweight form factor suitable for pediatric use. Through the support of the Shriner's Hospitals in Salt Lake City, U ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  4. A Breath-based Naltrexone Adherence Tool to Manage Narcotic-addicted HIV patients

    SBC: XHALE, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): Addiction annually costs America gt 500B. Narcotic addiction is especially worrisome since intravenous drug abuse (IVDA) also promotes HIV transmission. Reducing IVDA is critical to lowering the incidence of HIV. Sincegt75% of IVDA is with opioids, effective treatment of opiate addiction should markedly reduce IVDA and lower HIV transmission rates. Naltrexone ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  5. A computational platform to improve the prioritization of drugs and target genes for therapeutic intervention

    SBC: Genetic Networks, LLC            Topic: 100

    Project Summary This project proposes further development of a computational discovery platform shown to quantifiably identify and prioritize both targets and compounds for therapeutic intervention, which will accelerate the development of newer, more effective drugs with fewer side-effects. This platform is based on a novel fusion of two state of the art computational approaches (phenolog mapping ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. A Dual-drug Delivery to Inhibit Causes of Periodontal Diseases

    SBC: RANN RESEARCH CORPORATION            Topic: NIDCR

    DESCRIPTION (provided by applicant): The pathogenicity of periodontal disease is linked mainly with gram-negative anaerobic bacteria and with tissue damage caused by the host response to infection. Therefore, adjuvant to conventional antimicrobial therapies, the modulation of host response to infection (termed as host modulatory therapy; HMT) must also be accompanied for its complete therapy. Non ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Advanced CLAD PERG system with minimal patient preparation for clinical settings

    SBC: JORVEC CORP.            Topic: N

    AbstractGlaucoma is one of a number of optic nerve diseases which lead to retinal ganglion cellsRGCdegenerationultimately manifesting in a functional loss of vision if left untreatedThere exist a number of therapeutic approaches to treat these conditionsbut there are currently no clinical methods to detect the onset of RGC dysfunctionThe Pattern ElectroretinogramPERGis the only established tool to ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Advanced development of a novel nanoparticle conjugate vaccine for Salmonella Paratyphi A

    SBC: KJ BIOSCIENCES LLC            Topic: NIAID

    Salmonella Paratyphi ASParatyphi Ais a major cause of life threatening enteric feverThere is no vaccine available against this pathogenIn the SBIR phase I studieswe have successfully demonstrated the technical feasibility of a novel nanoparticle conjugate vaccine candidate for SParatyphi AIt is based on O polysaccharideOPSantigen conjugated to a novel and highly advantageous nanoparticle protein c ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Advanced Manufacturing and Material Measurements Software Tool Weave ™ for the Acceleration and Automation of SEM Image Analysis in the Semiconductor Industry

    SBC: Sandbox Semiconductor Incorporated            Topic: None

    In this Phase I SBIR proposal, SandBox Semiconductor™ proposes to develop an Advanced Manufacturing and Material Measurements software tool called Weave ™ for accelerating and automating SEM image analysis for the semiconductor industry. During the development of a new manufacturing process line for a semiconductor device, tens of thousands of scanning electron microscopy (SEM) images are take ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  10. Advance Early Detection of Lupus Nephritis with ClearGold

    SBC: CLEARNANO INC            Topic: 400

    SummarySystemic lupus erythematosusSLEor lupus is an autoimmune disease that impacts more thanmillion people worldwideincludingmillion AmericansNearlyof these patients will develop lupus nephritiswhich can cause kidney failureAs a resultits financial burden to individual patient can reach $yearmuch higher than many other diseases because of kidney transplantationAlthough early treatment of lupus n ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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