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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. DISTRIBUTED DATA MANAGEMENT FOR CANCER CLINICAL TRIALS

    SBC: American Power Jet Company            Topic: N/A

    THIS PROPOSAL SEEKS TO DEVELOP AND IMPLEMENT A DISTRIBUTED DATA MANAGEMENT NETWORK FOR CANCER CLINICAL TRIALS. THE NETWORK WILL BE MICROCOMPUTER BASED AND WILL HAVE AS ITS OBJECTIVE A CENTRALIZED DATABASE FOR MONITORING THE PROGRESSOF CLINICAL TRIALS. FEATURES WILL INCLUDE DATA ENTRY USING PREFORMATTED SCREENS, AUTOMATED ERROR CHECKING, EDITING FACILITIES, DATA SECURITY, AND DATA TRANSFER CAPABILI ...

    SBIR Phase I 1987 Department of Health and Human Services
  2. MOLECULAR ANALYSIS OF TK AND HPRT GENE MUTATIONS IN L5178Y MOUSE LYMPHOMA CELLS

    SBC: APPLIED GENETICS LABORATORIES            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  3. AUTOMATED ELECTROPHYSIOLOGIC HEARING SCREENING DEVICE

    SBC: Artificial Hearing Systems Cp            Topic: N/A

    HEARING TESTING OF NEWBORNS AND INFANTS USING AUDITORY BRAINSTEM RESPONSES (ABR) HAS GAINED WIDESPREAD ACCEPTANCE AND HAS COME TO BE PREFERRED OVER OTHER LESS ACCURATE TECHNIQUES. ABR'S STRENGTH IS ITS DIRECT MEASUREMENT OF AUDITORY FUNCTION, WHICH RESULTS IN HIGH TEST SPECIFICITY AND SENSITIVITY. CLINICAL USE OF ABR, HOWEVER, IS STILL LIMITED BECAUSE OF THE PROFESSIONAL LABOR-INTENSIVE OPERATION ...

    SBIR Phase II 1987 Department of Health and Human Services
  4. NEUROANATOMY WORKSTATION AND KNOWLEDGE ENGINEERING

    SBC: BIOGRAPHICS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  5. DIMETHYLSUBERIMIDATE AS A PULPOTOMY AGENT

    SBC: Biomedical Development Corporation            Topic: N/A

    THE LONG-TERM GOAL OF THIS APPLICATION IS TO DEVELOP DIMETHYLSUBERIMIDATE (DMS) AS AN ALTERNATIVE PULP THERAPY. FORMOCRESOL, THE DRUG MOST COMMONLY USED FOR TREATMENT OF CARIOUSLY EXPOSED PULPS OF THE PRIMARY DENTITION, IS TOXIC TO THE TREATED TISSUE, INDUCES ANTIGEN FORMATION AND SUBSEQUENT CHRONIC INFLAMMATION, IS RAPIDLY DISTRIBUTED SYSTEMICALLY, AND HAS MUTAGENIC POTENTIAL. FORMOCRESOL PULPOTO ...

    SBIR Phase II 1987 Department of Health and Human Services
  6. LIPID POLYMER FILMS-A NOVEL BIOMATERIAL

    SBC: Biotechnology Associates Inc            Topic: N/A

    BIOTECHNOLOGY ASSOCIATES, INC. WILL DEVELOP SURFACE COATINGS COMPOSED OF FILMS OF POLYMERIZED LIPIDS THAT WILL BE NONTHROMBOGENIC AND NONADHESIVE FOR CELLS. THUS THEY MAY PROVIDE USEFUL BIOCOMPATIBLE COATINGS FOR BIOMEDICAL DEVICES. LIPID POLYMER FILMS WILL ALSO BE MODIFIED BY COUPLING OF ADHESION PROTEINS OR PEPTIDES TO PROVIDE SURFACES WITH CONTROLLED CELL ADHESION PROPERTIES IN THE ABSENCE OF S ...

    SBIR Phase I 1987 Department of Health and Human Services
  7. ECCENTRIC CONTRACTIONS EFFECTS ON MUSCULOSKELETAL AGING

    SBC: Design/analysis Services Co            Topic: N/A

    OSTEOPOROSIS, DEGENERATIVE JOINT DISEASE, AND PRIMARY MUSCLE ATROPHY ARE THREE AGE-RELATED DISORDERS OF THE MUSCULOSKELETAL SYSTEM. OSTEOPOROSIS AFFECTS 90 PERCENT OF WOMEN OVER 75 YEARS, OSTEOARTHRITIS AFFLICTS 80 PERCENT, AND MUSCLE ATROPHY IS PROGRESSIVE WITH AGE. PHYSICAL CONDITIONING RETARDS BONE LOSS, STABILIZES DETERIORATED JOINTS, AND PREVENTS MUSCLE ATROPHY. THE MOST EFFICIENT STIMULUS TO ...

    SBIR Phase I 1987 Department of Health and Human Services
  8. DEVELOPMENT OF A RAPID IMMUNOASSAY FOR SYPHILIS

    SBC: Diamedix Corpon            Topic: N/A

    SYPHILIS, STILL A MAJOR SERIOUS INFECTIOUS DISEASE, CAN BE TREATED EFFECTIVELY IF DIAGNOSED EARLY. THE NUMBER OF DEATHS FROM SYPHILIS IN THE UNITED STATES HAS SHOWN A STEADY DECREASE, BUT THE NUMBER OF SYPHILIS CASES HAS NOT SHOWN A SIGNIFICANT DROP. SEROLOGICAL TESTS PLAY A MAJOR ROLE IN THE DIAGNOSIS OF SYPHILIS. THESE TESTS MUST BE PERFORMED BY QUALIFIED TECHNICIANS IN A LABORATORY. THE PROPOSE ...

    SBIR Phase I 1987 Department of Health and Human Services
  9. MICROCOMPUTER ASSISTED PROCEDURES FOR CYTOGENETICS

    SBC: Genetics Data Services Inc.            Topic: N/A

    THE DEVELOPMENT OF A MICROCOMPUTER-BASED CHROMOSOME ANALYSIS SYSTEM IS PROPOSED HERE TO ENABLE A TRAINED CYTOGENETICIST TO ANALYZE CLINICAL CHROMOSOME PREPARATIONS MORE EFFICIENTLY AND ACCURATELY. IN CONTRAST TO SOME MINICOMPUTER-BASED CHROMOSOME ""IDENTIFICATION'' SYSTEMS CURRENTLY UNDER DEVELOPMENT OR BEING ACTIVELY MARKETED, THE PROPOSED SYSTEM WOULD ALLOW THE TRAINED CYTOGENETICIST TO DO THE A ...

    SBIR Phase II 1987 Department of Health and Human Services
  10. GASTROINTESTINAL ENDOSCOPIC OPTICAL FIBER FLUORIMETRY

    SBC: I.v.p. Company            Topic: N/A

    RESEARCH ON NOVEL GASTROINTESTINAL ENDOSCOPIC OPTICAL FIBER FLUORIMETRY (GEOFF) SENSORS IS PROPOSED IN ANSWER TO THE EMPHATIC NEED FOR SIGNIFICANT GAINS IN NEW AND BETTER SENSORDEVICES IN CONNECTION WITH RESEARCH, DIAGNOSTIC, AND THERAPEUTIC ENDOSCOPIC PROCEDURES. THE MERITS OF PROMISING SINGLE- OR MULTI-STRANDED AND DISPOSABLE OPTICAL FIBER FLUORIMETRY SENSORS CONFIGURED TO AUGMENT THE FIBEROPTIC ...

    SBIR Phase I 1987 Department of Health and Human Services

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