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DESCRIPTION provided by applicant Periodontal bone regeneration requires attention to a the need of a physical barrier to restrict the entry formation of fibro epithelial tissue b he cause of bone loss that is due to hostandapos s inflammatory response to pathological cause and not due to the causative pathogen directly so along with bone regeneration strategies the process also equally ...

THE TOPIC OF THIS PROPOSAL IS THE DESIGN OF AN ENVIRONMENTALCONTROL SYSTEM FOR THE MORE THAN TWO MILLION INDIVIDUALS IN THE UNITED STATES WHOSE PHYSICAL AND/OR MENTAL IMPAIRMENTS ARE SO SEVERE THAT THEY ARE UNABLE TO FUNCTION IN THEIR ENVIRONMENT IN A NORMAL AND EFFECTIVE MANNER. A TWO-YEAR COLLABORATIVE RESEARCH EFFORT BETWEEN THE BIOENGINEERING PROGRAM AT THE NATIONAL HEADQUARTERS OF THE ASSOCIA ...

Project Summary This project proposes further development of a computational discovery platform shown to quantifiably identify and prioritize both targets and compounds for therapeutic intervention, which will accelerate the development of newer, more effective drugs with fewer side-effects. This platform is based on a novel fusion of two state of the art computational approaches (phenolog mapping ...

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AbstractGlaucoma is one of a number of optic nerve diseases which lead to retinal ganglion cellsRGCdegenerationultimately manifesting in a functional loss of vision if left untreatedThere exist a number of therapeutic approaches to treat these conditionsbut there are currently no clinical methods to detect the onset of RGC dysfunctionThe Pattern ElectroretinogramPERGis the only established tool to ...

Knowledge Based Systems, Inc. (KBSI) will design and demonstrate an Advanced Cyber Threat Intelligence and Vulnerability Analysis Training Environment (ACTIVATE) framework that directly targets the need for advanced cyber network defense training. The proposed new enabling capability will support cyber training against an intelligent red team to enhance cyber operator trainee cyber-attack recognit ...

Salmonella Paratyphi ASParatyphi Ais a major cause of life threatening enteric feverThere is no vaccine available against this pathogenIn the SBIR phase I studieswe have successfully demonstrated the technical feasibility of a novel nanoparticle conjugate vaccine candidate for SParatyphi AIt is based on O polysaccharideOPSantigen conjugated to a novel and highly advantageous nanoparticle protein c ...

Preliminary definition and analysis of Ballistic Missile Defense System (BMDS) requirements in an isolated, manual, and loosely controlled change environment shows significant overlap in effort, resulting in a major increase to cost, schedule, mission classification, subsystem propagation, and trace of system impacts. To assist MDA with movement of BMDS mission objectives to mission requirements, ...

Knowledge Based Systems, Inc. (KBSI) proposes to conduct research and development leading to the Advanced Distributed and Parallel Technologies for System-of-Systems Modeling & Simulation (ADAPTATION) toolkit and supporting discipline. The proposed toolkit will enable simulation event team members and stakeholders to better manage data and metadata and will improve verification and validation pro ...

Over 95% of the multilayer ceramic capacitors manufactured worldwide use base metal electrode (BME) technology and they are one of the key components in much of the modern electronics. BME capacitors have, over the last 20 years, made significant improvements in performance and reliability; making them more competitive for a wide range of applications. However, there remains significant concerns ...