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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Biosynthetic Degradable Textile for Soft Tissue Reconstruction

    SBC: Deep Blue Medical Advances, Inc.            Topic: 300

    AbstractBiosynthetic or synthetic degradable hernia mesh is the fastest growing segment of the hernia mesh marketreaching$M in sales inwith Bard controllingof the US marketfollowed by GoreNovus Scientificand EthiconWhile biosynthetic mesh may be used in any type of hernia repairit is most commonly used in ventral hernia repair cases where there is an increased risk of bacterial infectionThe reason ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Ablation of the pathogenic RNA transcript associated with myotonic dystrophy, DM1

    SBC: ENZERNA BIOSCIENCES LLC            Topic: NIAMS

    ABSTRACTMyotonic muscular dystrophyDMDis a genetic disorder characterized by muscle degeneration and weaknessIt is a common form of muscular dystrophy that generally begins in adulthoodUnfortunatelythere are no approved curative therapies for DMtreatments are largely palliativeThe more severe formmyotonic dystrophy typeDMis caused by theCTG n expansion in theUTR of the dystrophia myotonica protein ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. A Clinical Trial Enrichment Tool Based on Subgroups Defined by Machine Learning Predictive Models

    SBC: ORIGENT DATA SCIENCES, INC.            Topic: 102

    ABSTRACT Neurodegenerative disordersincluding amyotrophic lateral sclerosisALSFriedreichandapos s ataxiaFAmultiple sclerosisMSDuchenne muscular dystrophyDMDAlzheimer s diseaseADParkinson s diseasePDand Huntington s diseaseHDare characterized by heterogeneous disease progressionEfforts to identify responder subgroups may uncover subgroups that are more homogeneous in disease related features than t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. A CLOSED SYSTEM FOR PATHOGEN REDUCTION OF RED BLOOD CELLS FOR TRANSFUSION

    SBC: ZATA PHARMACEUTICALS, INC.            Topic: NHLBI

    ABSTRACT ZATA PharmaceuticalsIncWorcesterMAand NYBCNew YorkNYpropose to develop a closeddisposable pathogen reduction systemZ Systemfor treatment of packed Red Blood CellspRBCfor transfusionThe versatility of the proposed technology allows for several versions of the Z Systems to be createdadapted to different regulatory environmentsand for treatment of whole blood and any of its componentsHowever ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. A cloud-based WGS platform for establishing phylogeny within epidemic outbreaks at hospitals

    SBC: ICBiome            Topic: NIAID

    Outbreaks have become a significant public threat in hospitalsimpacting both patient lives and creating a financial burdenWith the increasing rise in antibiotic resistancenew interventions are urgently needed to contain ongoing outbreaksRecent studies have confirmed that whole genome sequencingWGSis able to identity unique mutations within each outbreak strainwhich can then be utilized to establis ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. A COMMUNICATION AND CONTROL SYSTEM FOR THE MENTALLY RETARDED

    SBC: Scott Instruments Corp            Topic: N/A

    THE TOPIC OF THIS PROPOSAL IS THE DESIGN OF AN ENVIRONMENTALCONTROL SYSTEM FOR THE MORE THAN TWO MILLION INDIVIDUALS IN THE UNITED STATES WHOSE PHYSICAL AND/OR MENTAL IMPAIRMENTS ARE SO SEVERE THAT THEY ARE UNABLE TO FUNCTION IN THEIR ENVIRONMENT IN A NORMAL AND EFFECTIVE MANNER. A TWO-YEAR COLLABORATIVE RESEARCH EFFORT BETWEEN THE BIOENGINEERING PROGRAM AT THE NATIONAL HEADQUARTERS OF THE ASSOCIA ...

    SBIR Phase I 1987 Department of Health and Human Services
  7. A Comprehensive Newborn Screening Solution for Duchenne and Congenital Muscular Dystrophies

    SBC: BAEBIES, INC.            Topic: NICHD

    Congenital genetic abnormalities are a leading cause of childhood mortality and morbidity. While routine newborn screening (NBS) has dramatically improved health outcomes, many congenital disorders such as Duchenne muscular dystrophy (DMD) and other congenital muscular dystrophies (CMD) are not currently detected by routine NBS. Presymptomatic identification through NBS is critical to facilitate e ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. A computational platform to improve the prioritization of drugs and target genes for therapeutic intervention

    SBC: Genetic Networks, LLC            Topic: 100

    Project Summary This project proposes further development of a computational discovery platform shown to quantifiably identify and prioritize both targets and compounds for therapeutic intervention, which will accelerate the development of newer, more effective drugs with fewer side-effects. This platform is based on a novel fusion of two state of the art computational approaches (phenolog mapping ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. ACOUSTIC MONITOR FOR KIDNEY/GALLSTONE BREAKUP BY LASERS

    SBC: PHYSICAL SCIENCES INC.            Topic: N/A

    A SERIES OF LABORATORY EXPERIMENTS WILL BE CONDUCTED TO INVESTIGATE THE FEASIBILITY OF USING AN ACOUSTIC-BASED DETECTION TECHNIQUE AS A REAL-TIME, IN SITU INDICATOR FOR LASER-INDUCED KIDNEY/GALLSTONE FRAGMENTATION. THE AIM WILL BE TO ESTABLISH A RELIABLE CORRELATION BETWEEN THE ACHIEVE- MENT OF STONE DEMISE DUE TO LASER-DRIVEN FRAGMENTATION AND THE RESULTING ACOUSTIC SIGNATURE GENERATED. IF SUCCES ...

    SBIR Phase II 1987 Department of Health and Human Services
  10. A Custom-Print Adjustable Force Magnetic Device for Severe Blepharoptosis

    SBC: Skelmet, Inc.            Topic: NEI

    Project SummaryAbstract This project aims to determine the technical merit and feasibility of using cranio facial scans to produce a customD printed spectacle device to treat severe ptosisinability to open the eyesThere are many causes of ptosisbut it is most severe and disabling after brainstem strokesevere head traumaand Myasthenia GravisThe devicereferred to as the Magnetic Levator ProsthesisML ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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