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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Clinical Trial Enrichment Tool Based on Subgroups Defined by Machine Learning Predictive Models

    SBC: ORIGENT DATA SCIENCES, INC.            Topic: 102

    ABSTRACT Neurodegenerative disordersincluding amyotrophic lateral sclerosisALSFriedreichandapos s ataxiaFAmultiple sclerosisMSDuchenne muscular dystrophyDMDAlzheimer s diseaseADParkinson s diseasePDand Huntington s diseaseHDare characterized by heterogeneous disease progressionEfforts to identify responder subgroups may uncover subgroups that are more homogeneous in disease related features than t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A cloud-based WGS platform for establishing phylogeny within epidemic outbreaks at hospitals

    SBC: ICBiome            Topic: NIAID

    Outbreaks have become a significant public threat in hospitalsimpacting both patient lives and creating a financial burdenWith the increasing rise in antibiotic resistancenew interventions are urgently needed to contain ongoing outbreaksRecent studies have confirmed that whole genome sequencingWGSis able to identity unique mutations within each outbreak strainwhich can then be utilized to establis ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. A collaborative data collection and analysis for inquiry-based experiential learning for health sciences related STEM education

    SBC: WICKED DEVICE LLC            Topic: 500

    Abstract The U.S. Department of Commerce predicts that STEM (science, technology, engineering, and math) jobs occupations will grow by 8.9 % from 2014 to 2024, compared to 6.4% for non-STEM occupations. STEM wages are generally higher than non-STEM, with a 29% difference in 2015. Yet, current approaches to STEM education are falling significantly short. In 2016, 64% of U.S. high school students un ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. A COMMUNICATION AND CONTROL SYSTEM FOR THE MENTALLY RETARDED

    SBC: Scott Instruments Corp            Topic: N/A

    THE TOPIC OF THIS PROPOSAL IS THE DESIGN OF AN ENVIRONMENTALCONTROL SYSTEM FOR THE MORE THAN TWO MILLION INDIVIDUALS IN THE UNITED STATES WHOSE PHYSICAL AND/OR MENTAL IMPAIRMENTS ARE SO SEVERE THAT THEY ARE UNABLE TO FUNCTION IN THEIR ENVIRONMENT IN A NORMAL AND EFFECTIVE MANNER. A TWO-YEAR COLLABORATIVE RESEARCH EFFORT BETWEEN THE BIOENGINEERING PROGRAM AT THE NATIONAL HEADQUARTERS OF THE ASSOCIA ...

    SBIR Phase I 1987 Department of Health and Human Services
  5. A computational platform to improve the prioritization of drugs and target genes for therapeutic intervention

    SBC: Genetic Networks, LLC            Topic: 100

    Project Summary This project proposes further development of a computational discovery platform shown to quantifiably identify and prioritize both targets and compounds for therapeutic intervention, which will accelerate the development of newer, more effective drugs with fewer side-effects. This platform is based on a novel fusion of two state of the art computational approaches (phenolog mapping ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. A deep learning platform to evaluate the reliability of scientific claims by citation analysis.

    SBC: Scite, Inc.            Topic: NIDA

    The opioid epidemic in the United States has been traced to aletter reporting in the prestigious New England Journal of Medicine that synthetic opioids are not addictiveA belated citation analysis led the journal to append this letter with a warning this letter has beenheavily and uncritically citedas evidence that addiction is rare with opioid therapyThis epidemic is but one example of how unreli ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A diabetes pill to replace insulin injections

    SBC: BIOORG3.14 LLC            Topic: 200

    The overall goal of this program is to develop an oral replacement for injecting insulin. The central premise of this work is that a small molecule called BG-148, or similar molecules, can be taken orally in place of injecting insulin to aid in glycemic control. BG-148 could completely replace insulin injections or could reduce insulin injections by half. To begin clinical testing to evaluate this ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. A DIGITAL SIGNAL PROCESSING EVOKED-POTENTIAL MACHINE

    SBC: Corpteks Inc.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  9. A DIGITAL TELEMETRY MONITOR WITH MODULAR FEATURES

    SBC: United States Control            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  10. A Disease-Modifying Protein Therapeutic for the Treatment of COPD

    SBC: VERRA THERAPEUTICS LLC            Topic: NHLBI

    Project Summary Abstract COPD is projected to become the third most common cause of death worldwideand we currently lack any medical therapies that significantly alter the course of this diseaseOur recent work identifies ADAMa disintegin and metalloproteinase domainas the first proteinase that promotes the three key COPD pulmonary pathologiesemphysemasmall airway fibrosisand airway mucus cell meta ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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