Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A COMMUNICATION AND CONTROL SYSTEM FOR THE MENTALLY RETARDED

    SBC: Scott Instruments Corp            Topic: N/A

    THE TOPIC OF THIS PROPOSAL IS THE DESIGN OF AN ENVIRONMENTALCONTROL SYSTEM FOR THE MORE THAN TWO MILLION INDIVIDUALS IN THE UNITED STATES WHOSE PHYSICAL AND/OR MENTAL IMPAIRMENTS ARE SO SEVERE THAT THEY ARE UNABLE TO FUNCTION IN THEIR ENVIRONMENT IN A NORMAL AND EFFECTIVE MANNER. A TWO-YEAR COLLABORATIVE RESEARCH EFFORT BETWEEN THE BIOENGINEERING PROGRAM AT THE NATIONAL HEADQUARTERS OF THE ASSOCIA ...

    SBIR Phase I 1987 Department of Health and Human Services
  2. A DIGITAL TELEMETRY MONITOR WITH MODULAR FEATURES

    SBC: United States Control            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  3. A FORMAL APPROACH TO TEACHING CHILDREN DECISION-MAKING SKILLS

    SBC: Decision Science Associates            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  4. A Biosynthetic Degradable Textile for Soft Tissue Reconstruction

    SBC: Deep Blue Medical Advances, Inc.            Topic: 300

    AbstractBiosynthetic or synthetic degradable hernia mesh is the fastest growing segment of the hernia mesh marketreaching$M in sales inwith Bard controllingof the US marketfollowed by GoreNovus Scientificand EthiconWhile biosynthetic mesh may be used in any type of hernia repairit is most commonly used in ventral hernia repair cases where there is an increased risk of bacterial infectionThe reason ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Ablation of the pathogenic RNA transcript associated with myotonic dystrophy, DM1

    SBC: Enzerna Biosciences LLC            Topic: NIAMS

    ABSTRACTMyotonic muscular dystrophyDMDis a genetic disorder characterized by muscle degeneration and weaknessIt is a common form of muscular dystrophy that generally begins in adulthoodUnfortunatelythere are no approved curative therapies for DMtreatments are largely palliativeThe more severe formmyotonic dystrophy typeDMis caused by theCTG n expansion in theUTR of the dystrophia myotonica protein ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. A Clinical Trial Enrichment Tool Based on Subgroups Defined by Machine Learning Predictive Models

    SBC: Origent Data Sciences, Inc.            Topic: 102

    ABSTRACT Neurodegenerative disordersincluding amyotrophic lateral sclerosisALSFriedreichandapos s ataxiaFAmultiple sclerosisMSDuchenne muscular dystrophyDMDAlzheimer s diseaseADParkinson s diseasePDand Huntington s diseaseHDare characterized by heterogeneous disease progressionEfforts to identify responder subgroups may uncover subgroups that are more homogeneous in disease related features than t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A cloud-based WGS platform for establishing phylogeny within epidemic outbreaks at hospitals

    SBC: ICBiome            Topic: NIAID

    Outbreaks have become a significant public threat in hospitalsimpacting both patient lives and creating a financial burdenWith the increasing rise in antibiotic resistancenew interventions are urgently needed to contain ongoing outbreaksRecent studies have confirmed that whole genome sequencingWGSis able to identity unique mutations within each outbreak strainwhich can then be utilized to establis ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. A Comprehensive Newborn Screening Solution for Duchenne and Congenital Muscular Dystrophies

    SBC: Baebies, Inc.            Topic: NICHD

    Congenital genetic abnormalities are a leading cause of childhood mortality and morbidityWhile routine newborn screeningNBShas dramatically improved health outcomesmany congenital disorders such as Duchenne muscular dystrophyDMDand other congenital muscular dystrophiesCMDare not currently detected by routine NBSPresymptomatic identification through NBS is critical to facilitate earlier initiation ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. A computational platform to improve the prioritization of drugs and target genes for therapeutic intervention

    SBC: Genetic Networks, LLC            Topic: 100

    Project Summary This project proposes further development of a computational discovery platform shown to quantifiably identify and prioritize both targets and compounds for therapeutic interventionwhich will accelerate the development of newermore effective drugs with fewer side effectsThis platform is based on a novel fusion of two state of the art computational approachesphenolog mapping and fun ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Adding SpO2 and Hemoglobin Determinations to Non-Invasive Hemodynamic Monitoring for Healthy Independent Living

    SBC: RFPi, Inc.            Topic: NHLBI

    Abstract Technologies to safelyeffectivelyand efficiently monitor clinical cardiovascular status in patients with one or more cardiovascular related diseases are an unmet need in healthcareSince small changes in clinical status can compound rapidlymonitoring a number of physiologic status parametersPSPssimultaneously and trending their changes over time is crucial for early interventionin order to ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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