Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. IMPACT-Instrument to Measure Pain and Assess Correlation to Treatment. Create a smartphone pupillometry to objectively determine the presence of acute pain, evaluate opioid as the treatment for pain.

    SBC: Benten Technologies, Inc.            Topic: NIDA

    PROJECT SUMMARY ABSTRACT While patient self report of pain is currently the gold standard of pain measurementaccurate self reports of pain may not be feasible in critically ill patients who are sedated and intubatedunconscious patientsor patients who are unable to verbally communicate their painCurrent research has shown that pupillary dilationPDis a reliable indicator of acute painand that measur ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. LATTICE: A Software Platform for Prospective and Retrospective Image Based Translational Research

    SBC: Translational Imaging Innovations, Inc.            Topic: NEI

    PROJECT SUMMARY Imaging forms the backbone of living subjects researchLiving subjects research is both essential to the progress of translational medicine and very expensiveThe research community actively seeks to develop and validate new clinical endpoints to solve a range of etiologynatural historydiagnostic and prognostic problemsThis project aims to develop and commercialize LATTICEan Electron ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. BEST-OUD: Behavioral Economic Screening Tool of Opioid Use Disorder for use in clinical practice

    SBC: BEAM Diagnostics, Inc.            Topic: 41

    PROJECT SUMMARY Fatal overdose from opioid misuse is one of the most pressing issues affecting the modern worldAs one of the nation s leading preventable causes of deatha critical line of defense against opioid use disorderOUDmust be standardized screening provided by the patient s primary care physicianpsychiatristand or counselorStandardized screening methods for opioidshoweverare simply inferio ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. An Instrument to Assess the Functional Impact of Chronic Pain

    SBC: BARRON ASSOCIATES, INC.            Topic: 999

    Project Summary Abstract Evaluation and treatment for chronic pain are major contributors to rising healthcare costsAlthough accurate assessment of pain and function is the cornerstone to successful chronic pain managementsystematicobjective assessment of the functional impact of pain remains exceptionally challenging in practiceThe intricate nature of chronic pain demands a comprehensivemulti mod ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Targeting neurotoxic alpha-synuclein aggregates for Parkinson's disease therapy.

    SBC: Vova Ida, LLC            Topic: 999

    SUMMARYParkinsonandapos s diseasePDis the second most prevalent neurodegenerative disorder after Alzheimerandapos s diseaseADaffecting more thanmillion people in the United StatesBecause age is the major risk factorthe prevalence of both diseases is steadily increasing as our population agesPD belongs to the group of protein misfolding neurodegenerative diseases that are due to the misfolding and ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Tuned stem cell extracellular vesicles are a novel chronic wound therapeutic

    SBC: ZEN-BIO, INC.            Topic: NIA

    Project Summary The elderly population is rapidly increasing worldwide and those overyears old are expected to compriseof the total population byThese demographic changes will focus healthcare needs on those conditions more prevalent in the elderlyChronic woundssuch as venous leg ulcerspressure ulcers and diabetic ulcers are over represented in the elderly population and even now present a signifi ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Next Generation Tools for Onsite Monitoring and Treatment of Drug of Abuse-Dependent Persons

    SBC: SensoDX II, LLC            Topic: NIDA

    Abstract Opioid abuse disorderOADaffectsmillion of Americans annually resulting in overdoses numbering in the tens of thousands and skyrocketing rates of mortalityIn addition to its enormous social impactOAD carries a multi billion dollar price tag that includes $billionspecifically for health care and other costs related to prescription opioid abuse and misuseAlthough effective interventions exis ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Resveratrol as a Corneal Pain Therapeutic

    SBC: TED'S BRAIN SCIENCE INCORPORATED            Topic: N

    More thanindividuals undergo laser vision correction surgery each year in the United Statesincluding laser assisted in situ keratomileusisLASIKand photorefractive keratectomyPRKThese procedures damage the nerves in the corneal epithelium causing intense acute pain that most patients rate as greater thanon ascalemany report the pain to beunbearableeven after analgesic treatmentWhile virtually all p ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Development of an Opioid Misuse Prevention Program for Young Adult Workers in the Construction Industry

    SBC: Prevention Strategies, LLC            Topic: NIDA

    Abstract Overmillion Americans agedor older reported opioid misuse inOverpeople died due to opioid related overdoses inupfromtoPreventing the onset of opioid misuse is critical for young adultswho representmillion past year opioid misusersOpioid misuse in this developmental period can negatively affect mentalphysicaland social well being and can lead to morbidity and mortality due to overdoseYoung ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A universal approach for improving the limit of detection for fentanyl and fentanyl derivatives in urine

    SBC: CERES NANOSCIENCES            Topic: NIDA

    PROJECT SUMMARY Prescription drug related adverse deaths rank as the fourth leading cause of death in the United StatesOpioid pain relievers constitute the most commonly abused class of drugsinvolved in overof all drug overdose deaths inMore people die from overdoses of prescription opioids than from all other drugs combinedincluding illegal drugsFentanyl is the most widely misused prescription op ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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