Award Data

AbstractBiosynthetic or synthetic degradable hernia mesh is the fastest growing segment of the hernia mesh marketreaching$M in sales inwith Bard controllingof the US marketfollowed by GoreNovus Scientificand EthiconWhile biosynthetic mesh may be used in any type of hernia repairit is most commonly used in ventral hernia repair cases where there is an increased risk of bacterial infectionThe reason ...

STUDIES ARE DESIGNED TO DEVELOP CORNEAL MASKS, FORMED IN SITU, WITH KNOWN CENTRAL RADII OF CURVATURE. MASK FORMATION WILL UTILIZE A NEW TECHNOLOGY, ALLOWING APPLICATION OF A VISCOUS FLUID TO SMOOTHE OVER ALL CORNEAL IRREGULARITIES BEFORE GELLING IN PLACE. MASK FIRMNESS WILL BE ACHIEVED CHEMICALLY IN THE PRESENCE OF A HARD CONTACT LENS. LENS REMOVAL WILL LEAVE AN ABLATABLE MASK OF THE SAME CURVATUR ...

ABSTRACTMyotonic muscular dystrophyDMDis a genetic disorder characterized by muscle degeneration and weaknessIt is a common form of muscular dystrophy that generally begins in adulthoodUnfortunatelythere are no approved curative therapies for DMtreatments are largely palliativeThe more severe formmyotonic dystrophy typeDMis caused by theCTG n expansion in theUTR of the dystrophia myotonica protein ...

ABSTRACT Neurodegenerative disordersincluding amyotrophic lateral sclerosisALSFriedreichandapos s ataxiaFAmultiple sclerosisMSDuchenne muscular dystrophyDMDAlzheimer s diseaseADParkinson s diseasePDand Huntington s diseaseHDare characterized by heterogeneous disease progressionEfforts to identify responder subgroups may uncover subgroups that are more homogeneous in disease related features than t ...

Outbreaks have become a significant public threat in hospitalsimpacting both patient lives and creating a financial burdenWith the increasing rise in antibiotic resistancenew interventions are urgently needed to contain ongoing outbreaksRecent studies have confirmed that whole genome sequencingWGSis able to identity unique mutations within each outbreak strainwhich can then be utilized to establis ...

THE TOPIC OF THIS PROPOSAL IS THE DESIGN OF AN ENVIRONMENTALCONTROL SYSTEM FOR THE MORE THAN TWO MILLION INDIVIDUALS IN THE UNITED STATES WHOSE PHYSICAL AND/OR MENTAL IMPAIRMENTS ARE SO SEVERE THAT THEY ARE UNABLE TO FUNCTION IN THEIR ENVIRONMENT IN A NORMAL AND EFFECTIVE MANNER. A TWO-YEAR COLLABORATIVE RESEARCH EFFORT BETWEEN THE BIOENGINEERING PROGRAM AT THE NATIONAL HEADQUARTERS OF THE ASSOCIA ...

Congenital genetic abnormalities are a leading cause of childhood mortality and morbidity. While routine newborn screening (NBS) has dramatically improved health outcomes, many congenital disorders such as Duchenne muscular dystrophy (DMD) and other congenital muscular dystrophies (CMD) are not currently detected by routine NBS. Presymptomatic identification through NBS is critical to facilitate e ...

Project Summary This project proposes further development of a computational discovery platform shown to quantifiably identify and prioritize both targets and compounds for therapeutic intervention, which will accelerate the development of newer, more effective drugs with fewer side-effects. This platform is based on a novel fusion of two state of the art computational approaches (phenolog mapping ...

THE LONG-TERM OBJECTIVE IS TO DEVELOP A COMPUTER-BASED YOUTH SUBSTANCE ABUSE FITNESS LIFE SKILLS TRAINING PRODUCT FOR HEALTH PROFESSIONALS, USING STATE-FO-THE-ART HARDWARE AND SOFTWARE TECHNOLGOY. A SYSTEMATIC CURRICULUM REQUIRING SIXTY-FOUR HOURS OF CLASSROOM TRAINING HAS BEEN DEVELOPED FOR HEALTH PROFESSIONALS TO DELIVER THE FITNESS LIFE SKILLS MODEL. HOWEVER, THE LENGTH AND EXPENSE REQUIRED TO ...

WE WILL DESIGN A COMPUTER-ASSISTED CONSUMERS GUIDE TO PROVIDE CONSUMERS IN THE DISABILITY COMMUNITY AND HEALTH CARE PROVIDERS DETAILED INFORMATION AS TO THEIR RIGHTS AND RESPONSIBILITIES UNDER THE AMERICANS WITH DISABILITIES ACT (ADA) WITH REGARD TO ACCESS TO HEALTH CARE SERVICES. THE ADA AND ITS REGULATIONS WILL BE CAREFULLY RESEARCHED. INPUT WILL BE OBTAINED FROM MEMBERS OF THE DISABILITY COMMUN ...