Award Data

To address the scarcity of effective treatments for volumetric muscle loss injuries, we propose a novel aligned multilumen nanofibrillar collagen scaffold loaded with Hepatocyte Growth Factor (HGF) modified messenger RNA (mmRNA) to direct functional muscl

The Phase I and Phase II projects that are the basis for this Phase II enhancement proposal tested the feasibility of releasing opiate compounds from a topical wound dressing for burn pain relief and treatment. This project culminated with a regulatory s

In this Small Business Innovative Research (SBIR) effort, Nikira Labs Inc. proposes to develop a compact Raman fiber optic probe with inline spectral filtering that improves fiber-coupled Raman measurements by filtering out Raman scattering from the excitation fiber and elastically scattered laser light from the collection fibers. The technology will enable compact fiber probes for Raman studies i ...

Problem: Currently available resuscitation fluids have been shown to induce detrimental effects on trauma outcomes. Objective: The objective of this proposal is to use the data from the successful Phase 1 studies to guide the continued development and te

NIST developed risk management framework and guidelines that assist agencies to implement integrated, organization‐wide programs to manage information security risk, and further developed Cloud Security Architecture Tool (CSAT) to facilitate in this matter. However, NIST’s CSAT needs further improvement and implementation of new functions such that it can be commercialized as an Enterprise‐g ...

Thegoal is to develop asoftwaretool that implementsa novelapproach applicableto fitgeneral pharmacologic, toxicology, or other biomedical data, that mayexhibita non-monotonic dose-responserelationship for which thecurrent parametricmodels fail. Thesoftwareexplores dose-responserelationships using both monotonicand non-monotonicmodels,and estimates theassociated doseresponsecurves,which can further ...

Joint reduction is a key skill and is a core competency for orthopedic surgeons deploying as part of a trauma team. Current training options are limited to classroom instruction on uninjured persons due to lack of a suitable training simulator. The first

Phase I has proven that the current setup achieves better than 8mm spatial resolution for 2.2MeV prompt gammas. However, 1mm spatial resolution presents a significant challenge for the current setup due in part to limited timing resolution and count rate. A new analog ASIC will be developed to replace the current analog ASIC that will have better timing resolution and deliver higher count rates. I ...

The CONOPS for the Expeditionary Medical Support System (EMEDS) is based on practical effectiveness, speed, and efficiency. Key among the tools required by the Air Mobility Command and the Air Combat Command, which are two of the major commands that are part of the United Air Force is a multi-channel intravenous infusion pump capable of delivering fluids that meets the safe-to-fly criteria for all ...

In a multiple patient situation, the medics need all the help they can get. Monitoring several patients is a difficult task, and associating the vital signs data with the right patient is crucial. Providing medics with a tool to assist in this task can gr