Award Data

In this Phase I SBIR proposal, SandBox Semiconductor™ proposes to develop an Advanced Manufacturing and Material Measurements software tool called Weave ™ for accelerating and automating SEM image analysis for the semiconductor industry. During the development of a new manufacturing process line for a semiconductor device, tens of thousands of scanning electron microscopy (SEM) images are take ...

The goal of medical simulation-based training such as high-fidelity manikin simulators, part task trainers, and screen-based virtual patients, is to approximate real-life treatment experiences without risk to live patients. While the use of sensors has ma

The Problem and CreateAbility Concepts Inc.'s Proposed SolutionThe life expectancy of the average American continues to increase as does the average age inrural America. Older adults (people 65 years and older) of today live longer and seek moreindependence than their predecessors just a decade ago. With this increased desire forindependence comes a growing emphasis on maintaining health and funct ...

This SBIR Phase I project proposes to develop an easy to use, inexpensive, and portable bacterial concentrator to enable more sensitive cholera pathogen (Vibrio cholerae) detection. Cholera affects communities across 41 countries, including Mozambique in 2019 after Cyclone Idai and Yemen in 2017. Current methods used to detect the cholera pathogen in water involves a 3 to 5-day procedure due to th ...

There is compelling value to feeding live algae in fish hatcheries as the current survival rate oflarvae fed frozen paste is relatively low resulting in higher costs.However the complexity andcosts of existing photo-bioreactors and the logistical costs of shipping live material over distancesare barriers to the widespread deployment of live algae as feed.Culture BioSystems has successfully grown a ...

THE U.S. POULTRY INDUSTRY ADMINISTERS ABOUT 21 BILLION DOSE UNITS OF VACCINES YEARLY. THESE VACCINATIONS ARE GIVEN TO TO DAY-OLD BIRDS FOR SEVERAL VIRAL AND BACTERIAL DISEASES, AND SUBSEQUENT VACCINATIONS TO GROWING AND ADULT CHICKENS ANAND TURKEYS. ADDITIONALLY, 170 MILLION TURKEY EMBRYOS R RECEIVE ANTIBIOTIC TREATMENT. THE WORLDWIDE POULTRY DRUG VACCINE MARKET REPRESENTS OVER $500 MILLION PR YEA ...

The Phase I and Phase II projects that are the basis for this Phase II enhancement proposal tested the feasibility of releasing opiate compounds from a topical wound dressing for burn pain relief and treatment. This project culminated with a regulatory s

Problem: Currently available resuscitation fluids have been shown to induce detrimental effects on trauma outcomes. Objective: The objective of this proposal is to use the data from the successful Phase 1 studies to guide the continued development and te

We have developed a bioinspired nanoparticle technology using the coat protein (CP) assemblies ofTobacco mild green mosaic tobamovirus (TMGMV) to deliver nematicides to roots reduce dosageand improve soil mobility efficacy and safety. The CP's zwitterionic nature allows the loading andrelease of nematicides. The TMGMV-delivered nematicides (TDN) are efficacious againstCaenorhabditis elegans in liq ...

Thegoal is to develop asoftwaretool that implementsa novelapproach applicableto fitgeneral pharmacologic, toxicology, or other biomedical data, that mayexhibita non-monotonic dose-responserelationship for which thecurrent parametricmodels fail. Thesoftwareexplores dose-responserelationships using both monotonicand non-monotonicmodels,and estimates theassociated doseresponsecurves,which can further ...