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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Advanced Manufacturing and Material Measurements Software Tool Weave ™ for the Acceleration and Automation of SEM Image Analysis in the Semiconductor Industry

    SBC: Sandbox Semiconductor Incorporated            Topic: None

    In this Phase I SBIR proposal, SandBox Semiconductor™ proposes to develop an Advanced Manufacturing and Material Measurements software tool called Weave ™ for accelerating and automating SEM image analysis for the semiconductor industry. During the development of a new manufacturing process line for a semiconductor device, tens of thousands of scanning electron microscopy (SEM) images are take ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Advanced Simulated Patient Intelligent Response Engine (ASPIRE)

    SBC: Vcom3D, Inc.            Topic: DHP191002

    The goal of medical simulation-based training such as high-fidelity manikin simulators, part task trainers, and screen-based virtual patients, is to approximate real-life treatment experiences without risk to live patients. While the use of sensors has ma

    SBIR Phase I 2019 Department of DefenseDefense Health Program
  3. Automated Modular Algae Cultivation For Aquaculture

    SBC: Culture Fuels, Inc.            Topic: 87

    There is compelling value to feeding live algae in fish hatcheries as the current survival rate oflarvae fed frozen paste is relatively low resulting in higher costs.However the complexity andcosts of existing photo-bioreactors and the logistical costs of shipping live material over distancesare barriers to the widespread deployment of live algae as feed.Culture BioSystems has successfully grown a ...

    SBIR Phase I 2019 Department of Agriculture
  4. AUTOMATIC EGG INJECTION MACHINE

    SBC: Embrex            Topic: N/A

    THE U.S. POULTRY INDUSTRY ADMINISTERS ABOUT 21 BILLION DOSE UNITS OF VACCINES YEARLY. THESE VACCINATIONS ARE GIVEN TO TO DAY-OLD BIRDS FOR SEVERAL VIRAL AND BACTERIAL DISEASES, AND SUBSEQUENT VACCINATIONS TO GROWING AND ADULT CHICKENS ANAND TURKEYS. ADDITIONALLY, 170 MILLION TURKEY EMBRYOS R RECEIVE ANTIBIOTIC TREATMENT. THE WORLDWIDE POULTRY DRUG VACCINE MARKET REPRESENTS OVER $500 MILLION PR YEA ...

    SBIR Phase II 1987 Department of Agriculture
  5. Clinical Evaluation of Biocompatible Dressings for the Delivery of Analgesics

    SBC: Keratin Biosciences Inc.            Topic: A14048

    The Phase I and Phase II projects that are the basis for this Phase II enhancement proposal tested the feasibility of releasing opiate compounds from a topical wound dressing for burn pain relief and treatment. This project culminated with a regulatory s

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  6. Complex Crystalloid Resuscitative Fluid

    SBC: GanD, Inc.            Topic: DHP172009

    Problem: Currently available resuscitation fluids have been shown to induce detrimental effects on trauma outcomes. Objective: The objective of this proposal is to use the data from the successful Phase 1 studies to guide the continued development and te

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  7. Delivery of nematicides to control plant parasitic nematodes by using Tobacco mild green mosaic tobamovirus as a nanocarrier

    SBC: BIOPRODEX INC            Topic: 82

    We have developed a bioinspired nanoparticle technology using the coat protein (CP) assemblies ofTobacco mild green mosaic tobamovirus (TMGMV) to deliver nematicides to roots reduce dosageand improve soil mobility efficacy and safety. The CP's zwitterionic nature allows the loading andrelease of nematicides. The TMGMV-delivered nematicides (TDN) are efficacious againstCaenorhabditis elegans in liq ...

    SBIR Phase I 2019 Department of Agriculture
  8. Developing Software for Pharmacodynamics and Bioassay Studies

    SBC: TConneX Inc.            Topic: DHP16C001

    Thegoal is to develop asoftwaretool that implementsa novelapproach applicableto fitgeneral pharmacologic, toxicology, or other biomedical data, that mayexhibita non-monotonic dose-responserelationship for which thecurrent parametricmodels fail. Thesoftwareexplores dose-responserelationships using both monotonicand non-monotonicmodels,and estimates theassociated doseresponsecurves,which can further ...

    STTR Phase II 2019 Department of DefenseDefense Health Program
  9. Development of a hormone implant to facilitate maturation and spawning in fish

    SBC: Live Advantage Bait, LLC            Topic: 87

    Hatchery production is one of the largest costs and restraints to fin fish aquaculture andspawning aids are ranked as a high priority drug required by the aquaculture industry.Exogenous hormone administration has been developed to induce maturation and obtainfertilized eggs.While the GnRH hormone and slow-release vehicle are not new theircombination into a commercialized product that can work be u ...

    SBIR Phase II 2019 Department of Agriculture
  10. Development of efficacious RNAi-based baits for RIFA control

    SBC: NANOSUR LLC            Topic: 82

    Imported Fire Ants (Solenopsis richteri Solenopsis invicta) are invasive pests which currentlyinfest over 140 million ha in 14 states. Damages related to fire ants have a significant impact onmany economic sectors including agriculture and biodiversity. The estimated annual cost spent onfire ant control is 3 billion dollars. Current chemical insecticides used in fire ant control are notselective c ...

    SBIR Phase I 2019 Department of Agriculture
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