Award Data

The main objective of this Phase II SBIR project is to evaluate a number of different self-healing tissue compositions suitable for incorporation into surgical training models.Successful implementation of Phase I formulations will be extended to a wider

The goal of medical simulation-based training such as high-fidelity manikin simulators, part task trainers, and screen-based virtual patients, is to approximate real-life treatment experiences without risk to live patients. While the use of sensors has ma

To address the scarcity of effective treatments for volumetric muscle loss injuries, we propose a novel aligned multilumen nanofibrillar collagen scaffold loaded with Hepatocyte Growth Factor (HGF) modified messenger RNA (mmRNA) to direct functional muscl

In order to meet Department of Defense, Defense Health Agency’s (DoD, DHA) need for a field-ready, antiseptic, warming, and pressure relieving casualty transport pad for up to 72 hours of litter evacuation, ChromoLogic proposes to develop an antiseptic, w

We propose development of an AR system that allows the medical personnel to visualize the internal anatomy of a patient by projecting relevant anatomical information onto the patient directly into the field of view (FOV) of the medic. With no medical imag

Current strategies for the treatment of osteochondral injuries are ineffective and are associated with significant side effects. Microfracture techniques have demonstrated limited efficacy over long periods of time and are less effective for larger osteochondral defects. Osteochondral autograft transplants require harvesting from a donor site, which can lead to donor site morbidity. Further, while ...

Snakebite is an occupational hazard for military personnel on every continent except Antarctica and an estimated 75% of fatalities from snakebite occur outside the hospital setting. Yet, no field antidote exists. Small molecule inhibition of snake venom sPLA2s and metalloproteases (svMP) will successfully treat most life- and limb-threatening snakebites without need for advanced treatment faciliti ...

Research has identified that handoffs are particularly important communication processes, during which communication error can lead to patient safety situations. Organizations have created standard practices and training materials to encourage teamwork communication for handoffs, however these do not necessarily capture the needs of military medicine of combat casualty care. Combat casualty handof ...

In order to meet DoDs need for in-line, non-invasive and non-destructive cell monitoring in dynamically growing cultures ChromoLogic proposes to develop a Cell Monitoring by Optical Coherence Tomography (CM-OCT) system that is based on Optical Coherence Tomography.By building on CLs 10+ years core competency in biophysics, bioengineering, tissue culture, and medical devices, CM-OCT is a device tha ...

The Phase I and Phase II projects that are the basis for this Phase II enhancement proposal tested the feasibility of releasing opiate compounds from a topical wound dressing for burn pain relief and treatment. This project culminated with a regulatory s