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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. BioloGel- Building Blocks for Osteochondral Regeneration

    SBC: Luna Innovations Incorporated            Topic: DHA17009

    Current strategies for the treatment of osteochondral injuries are ineffective and are associated with significant side effects. Microfracture techniques have demonstrated limited efficacy over long periods of time and are less effective for larger osteochondral defects. Osteochondral autograft transplants require harvesting from a donor site, which can lead to donor site morbidity. Further, while ...

    SBIR Phase II 2018 Department of DefenseDefense Health Program
  2. Complex Crystalloid Resuscitative Fluid

    SBC: GanD Inc            Topic: DHA172009

    The published data has demonstrated that the currently available resuscitation fluids have detrimental effects on trauma outcomes.By addressing these deficiencies it is expected that the outcomes will improve. The crystalloid based resuscitation fluid in development by GanD Inc. has been designed to address all of the shortcomings of the currently available solutions.The solution, GND-001, is a cr ...

    SBIR Phase I 2018 Department of DefenseDefense Health Program
  3. Complex Crystalloid Resuscitative Fluid

    SBC: GanD Inc            Topic: DHA172009

    Problem: Currently available resuscitation fluids have been shown to induce detrimental effects on trauma outcomes.Objective: The objective of this proposal is to use the data from the successful Phase 1 studies to guide the continued development and testing of the novel resuscitation fluid (GND-001), which has been designed to address the deficiencies of current resuscitation fluids.Proposed work ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  4. Developing Software for Pharmacodynamics and Bioassay Studies

    SBC: TCONNEX INC.            Topic: DHP16C001

    The goal is to develop a software tool that implements a novel approach applicable to fit general pharmacologic, toxicology, or other biomedical data, that may exhibit a non-monotonic dose-response relationship for which the current parametric models fail.The software explores dose-response relationships using both monotonic and non-monotonic models, and estimates the associated dose-response curv ...

    STTR Phase II 2018 Department of DefenseDefense Health Program
  5. Development of the JoRT Platform for Realistic Joint Reduction Training

    SBC: Luna Innovations Incorporated            Topic: DHA173002

    Joint reduction is a key skill and is a core competency for orthopedic surgeons deploying as part of a trauma team.Current training options are limited to classroom instruction on uninjured persons due to lack of a suitable training simulator. The first true reduction performed by medical providers is on actual patients. This method of instruction prevents the trainee from developing the comfort a ...

    SBIR Phase I 2018 Department of DefenseDefense Health Program
  6. Development of the JoRT Platform for Realistic Joint Reduction Training

    SBC: Luna Innovations Incorporated            Topic: DHA173002

    Joint reduction is a key skill and is a core competency for orthopedic surgeons deploying as part of a trauma team.Current training options are limited to classroom instruction on uninjured persons due to lack of a suitable training simulator. The first true reduction performed by medical providers is on actual patients. This method of instruction prevents the trainee from developing the comfort a ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  7. Dynamic virtual moulage based on thin film adhesive displays

    SBC: ARCHIE MD INC.            Topic: DHA17A002

    Providing Army combat medics with meaningful experience in treatment of battlefield injuries is a particular challenge. Moulage has the potential to assist in acquiring what could otherwise be very hard-to-come-by preparatory experience for distressing real-life emergencies medics and soldiers may encounter in the field. However, current approaches to moulage are limited in their ability to reflec ...

    STTR Phase II 2018 Department of DefenseDefense Health Program
  8. Field portable Coliform bacteria & E. Coli RNA biomarker LAMP- OSD system

    SBC: Fabrico Technology, Inc.            Topic: DHA17004

    Fabrico Technology, Dr. Sanchita Bhadra and Professor Andrew Ellington of the University of Texas at Austin, have successfully demonstrated the proof-of-concept of an unparalleled, first-in-class in-field nucleic acid diagnostic platform for distinction of viable from non-viable E. coli and coliforms in

    SBIR Phase II 2018 Department of DefenseDefense Health Program
  9. Functionalized, Therapeutic-Loaded Liposomes for the Acute Treatment of TBI

    SBC: Luna Innovations Incorporated            Topic: DHA18A001

    Traumatic brain injury is a common problem in both the military and civilian communities, but current treatment protocols are focused on managing symptoms and fail to prevent significant long-term repercussions. In the proposed program, Luna will demonstrate the feasibility of a liposome-based therapeutic delivery system capable of delivering hydrophilic and hydrophobic therapeutics to the traumat ...

    STTR Phase I 2018 Department of DefenseDefense Health Program
  10. Injectable Bio-compatible gel composed of iPSC derived NSC for regeneration of brain tissue

    SBC: Fabrico Technology, Inc.            Topic: DHA18004

    Stem cell apoptosis occurs when the interaction between the host brain extracellular matrix (ECM) and human induced pluripotent stem cell (iPSC) derived neural stem cell (NSCs) are directly injected into the injured brain regions. Establishment of a connection between ECM and iPSC/NSC could increase cell viability, differentiation, and promote functional recovery of the injured tissue. The critica ...

    SBIR Phase I 2018 Department of DefenseDefense Health Program

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