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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A2A receptor blockade for sepsis

    SBC: Purine Pharmaceuticals Inc.            Topic: NIAID

    SUMMARY Sepsis is a clinical syndrome that complicates severe infectionSepsis remains the leading cause of morbidity and mortality in critically ill patientsThere are no specific FDA approved medicines for the treatment of sepsisCurrent concepts of the pathophysiology of sepsis suggest that organ failure and mortality in sepsis are caused by inappropriate regulation of the immune systemThis manife ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A Biodégradable and Biomimetic Xerogel for Periodontal Bone Regeneration

    SBC: INNOVATIVE RESEARCH SOLUTIONS INC            Topic: NIDCR

    DESCRIPTION provided by applicant Periodontal bone regeneration requires attention to a the need of a physical barrier to restrict the entry formation of fibro epithelial tissue b he cause of bone loss that is due to hostandapos s inflammatory response to pathological cause and not due to the causative pathogen directly so along with bone regeneration strategies the process also equally ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. A BIOREACTOR FOR SCRENNING AND PRODUCTION OF HIGH VALUE SECONDARY PLANT METABOLITES

    SBC: Phytoresource Research Inc            Topic: N/A

    THE BIOCHEMICAL AND SYNTHETIC CAPACITY OF HIGHER PLANTS, AS SHOWN BY THEIR NATURAL CONTENT OF SUBSTANCES, HAS BEEN USED FOR CENTURIES IN SUPPLYING MATERIALS IMPORTANT IN PHARMACOLOGY AND IN FLAVORS AND FRAGRANCES. MANY OF THESE SECONDARY PRODUCTS ARE IN SHORT SUPPLY AND AN ENORMOUS EFFORT HAS TO BE EXTENDED TO GET THEM. ATTEMPTS TO USE CELL CULTURES OF HIGHER PLANTS AS A MEANS OF PRODUCING SECONDA ...

    SBIR Phase I 1987 National Aeronautics and Space Administration
  4. Ablative Material for Missile Launchers

    SBC: TEXAS RESEARCH INSTITUTE , AUSTIN, INC.            Topic: N181060

    The Navy wants the capability of firing over twenty missiles with Mark 72 boosters compared to about a dozen today, which will require a different ablative material than what is currently used. A solution to this problem is needed to get ahead of the curve for the future fleet operations. There is an opportunity to develop new ablative materials for the Mark 41 Vertical Launch System (VLS) with th ...

    SBIR Phase II 2019 Department of DefenseNavy
  5. ABSORPTION DIGITAL REFRACTOMETRY

    SBC: Measurement Concept Corp            Topic: N/A

    THIS PROPOSAL DESCRIBES A NEW METHOD FOR DETERMINING THE REFRACTIVE INDEX AND EXTINCTION COEFFICIENT OF OPTICAL MATERIALS. THIS METHOD IS AN OPTO-ELECTRONIC METHOD, IS COMPLETELY AUTOMATED, EXTREMELY FAST AND IS CAPABLE OF OBTAINING ACCURACIES AND RESOLUTIONS COMPARABLE WITH PRISM SPECTROMETERS. THIS MEASUREMENT METHOD IS CALLED ABSORPTIONDIGITAL REFRACTOMETRY. THE MOST ACCURATE METHOD AT PRESENT ...

    SBIR Phase I 1987 National Science Foundation
  6. Accelerated Drug Design Through Computational Biology

    SBC: Pbl Biomedical Laboratories            Topic: A03165

    Modern drug discovery is facilitated by investigating, understanding and exploiting the interaction of defined molecules within complex biological systems. The interface of computational and biomolecular sciences enables the exploitation and development of new paradigms for production of vital therapeutic agents. Success in the contemporary biopharmaceutical arena will require improvements in comp ...

    SBIR Phase II 2004 Department of DefenseArmy
  7. Accelerated Drug Design Through Computational Biology

    SBC: Pbl Biomedical Laboratories            Topic: A03165

    Our initiative to design agents to combat Plasmodium falciparum, the most debilitating of several malaria strains, combines powerful bioinformatic techniques to develop protein target structures with a multifaceted strategy for rational drug design. Using the available x-ray crystal structure of CDK2 as a structural template, we will generate and validate three-dimensional structural models of th ...

    SBIR Phase I 2004 Department of DefenseArmy
  8. Accelerating Memory-Access-Limited HPC Applications via Novel Fast Data Compression

    SBC: Accelogic, LLC            Topic: S501

    A fast-paced continual increase on the ratio of CPU to memory speed feeds an exponentially growing limitation for extracting performance from HPC systems. Ongoing developments and trends make it clear that this ratio will keep increasing over the next decade. Breaking this memory wall is one of the most important challenges that the HPC community faces today. In this project we introduce novel and ...

    SBIR Phase I 2015 National Aeronautics and Space Administration
  9. ACE: Application toolkit for Collaborative Environments

    SBC: MODUS OPERANDI, INC.            Topic: AF03094

    This ACE Phase II SBIR proposes an innovative approach to providing universal access to enterprise knowledge in order to meet critical needs of both government and commercial organizations. This SBIR will be conducted in close concert with the 45th Space Wing (45 SW) of the Air Force Space Command. 45 SW provides space launch and range support for the Air Force, DoD, civil, and commercial custom ...

    SBIR Phase II 2004 Department of DefenseAir Force
  10. A clinically Practical 6.45 mum Pulsed Surgical Laser

    SBC: LIGHT AGE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): An extensive research spent identifies, clinically significant contexts, effort have been to within various the wavelengths and wavelength ranges that optimize the interaction of laser radiation and human tissues

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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