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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Targeting neurotoxic alpha-synuclein aggregates for Parkinson's disease therapy.
SBC: Vova Ida, LLC Topic: 999SUMMARYParkinsonandapos s diseasePDis the second most prevalent neurodegenerative disorder after Alzheimerandapos s diseaseADaffecting more thanmillion people in the United StatesBecause age is the major risk factorthe prevalence of both diseases is steadily increasing as our population agesPD belongs to the group of protein misfolding neurodegenerative diseases that are due to the misfolding and ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Next Generation Tools for Onsite Monitoring and Treatment of Drug of Abuse-Dependent Persons
SBC: SensoDX II, LLC Topic: NIDAAbstract Opioid abuse disorder (OAD) affects 2.1 million of Americans annually resulting in overdoses numbering in the tens of thousands and skyrocketing rates of mortality. In addition to its enormous social impact, OAD carries a multi-billion-dollar price tag that includes $78.5 billion, specifically for health care and other costs related to prescription opioid abuse and misuse. Although effect ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Resveratrol as a Corneal Pain Therapeutic
SBC: TED'S BRAIN SCIENCE INCORPORATED Topic: NMore thanindividuals undergo laser vision correction surgery each year in the United Statesincluding laser assisted in situ keratomileusisLASIKand photorefractive keratectomyPRKThese procedures damage the nerves in the corneal epithelium causing intense acute pain that most patients rate as greater thanon ascalemany report the pain to beunbearableeven after analgesic treatmentWhile virtually all p ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Validation of a Cranial Neurosurgery Simulator and Assessment of Minimally Invasive Techniques
SBC: Simulated Inanimate Models LLC Topic: 103Project SummarySimulation training is unique in its ability for repetitive practice of a wide variety of scenarios and to reflect on performance without jeopardizing a patient s safetySurgical skills simulators have been successful in bridging gaps of the current training modelhoweverthese simulators fall short of offering a complete operative experienceOperative exposure with live patients still ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A Novel Chemokine Receptor Antagonist to Block Opioid Reinforcement, Relapse and Physical Dependence
SBC: CREATIVE BIO-PEPTIDES INC Topic: NIDAProject Summary Abstract This SBIR application is proposed in response to RFA DAthe HEAL Initiative on building technologies to stop the opioid crisisCreative Bio PeptidesIncis committed to providing effective and safe non opioid treatments for themillion Americans suffering daily pain and themillion who live with opioid dependency or addictionCurrent decades old addiction treatments like methadon ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Molecular Biomarkers of Dangerous Intracranial Aneurysms
SBC: NEUROVASCULAR DIAGNOSTICS, INC. Topic: 103Abstract Rupture of intracranial aneurysmsIAscauses intracranial hemorrhaging that leads to high rates of neurological deficits and deathAlthough rupture rates are lowclinicians must decide whether to treat or monitor these potentially dangerous lesionsIn the current clinical practicethe most common metric to measure risk of rupture is aneurysm sizemm ormmHoweverclinical data show that small aneur ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A deep learning platform to evaluate the reliability of scientific claims by citation analysis.
SBC: Scite, Inc. Topic: NIDAThe opioid epidemic in the United States has been traced to aletter reporting in the prestigious New England Journal of Medicine that synthetic opioids are not addictiveA belated citation analysis led the journal to append this letter with a warning this letter has beenheavily and uncritically citedas evidence that addiction is rare with opioid therapyThis epidemic is but one example of how unreli ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
User-driven Retrospectively Supervised Classification Updating (RESCU) system for robust upper limb prosthesis control
SBC: INFINITE BIOMEDICAL TECHNOLOGIES, LLC Topic: 105TBD
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Transcutaneous auricular neurostimulation for neonatal abstinence syndrome
SBC: SPARK BIOMEDICAL INC. Topic: R43Neonatal abstinence syndromeNASis a condition in which infants undergo withdrawal after exposure to prescription or non prescription opioids such as methadone or heroin in uteroNAS babies exhibit hyperirritability of the central nervous system and respiratorygastrointestinaland autonomic symptomsThese symptoms usually appear withintohours after birthAs ofan infant with NAS was born everyminutes in ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Novel Strategies for Development of a Multiplexed Test with Expanded Content for Spinal Muscular Atrophy
SBC: ASURAGEN, INC. Topic: 102SummaryThe overall goal of this project is to develop a cost effective multiplexed diagnostic test for spinal muscular atrophySMAto rapidly and accurately analyze multiple classes of disease causingdisease modifying DNA variantsand carrier status markersUltimatelythe proposed test will have a far reaching impact by expanding the identification and stratification of patients who may benefit from ne ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health