Award Data

This project will develop a new scientific instrument optimized for the advanced characterization of near-infrared fluorescent nanoparticles that can exist as left- or right-handed structures (enantiomers). Single-walled carbon nanotubes (SWCNTs) are the leading current example of such nanomaterials. Applied NanoFluorescence, LLC (ANF) proposes a novel multi-mode chiroptical spectrometer that can ...

The main focus of this SBIR Phase II project is to develop a prototype instrument and test cartridges for injectability pre-screening of high concentration protein formulations (HCFs). HCFs are non-Newtonian fluids with shear-thinning behavior and they are formulated to be administered by subcutaneous or muscular injections. The injectability and manufacturability of HCFs depend on the viscosity b ...

The goal of this proposal is to create the software Weave™ to automate the extraction of critical dimensions (CDs) from scanning electron microscope (SEM) images for the microelectronics industry. Current best practices for extraction of CDs are that personnel analyze the images one by one, which is tedious, prone to human bias, time-consuming and expensive. Successful implementation of Weave™ ...

Today’s Computer-Aided Design (CAD) applications utilize restrictive mathematical assumptions to approximate the compound geometric intersections necessary to represent real-world products. As a result, critical information is not represented within the Model-Based Definition (MBD) for downstream users in the digital thread, forcing engineers to manually repair CAD models and convert them into d ...

Modern Model-Based Enterprise / Engineering (MBE) systems rely on freeform surfaces built as complex combinations of geometric primitives to define engineered objects. Unfortunately, the intersection of freeform surfaces in MBE applications results in highly approximated solutions, degrading models that cost billions annually by US industry to fix. Current technology limits the abilities of users ...

The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

In this Phase I SBIR proposal, SandBox Semiconductor™ proposes to develop an Advanced Manufacturing and Material Measurements software tool called Weave ™ for accelerating and automating SEM image analysis for the semiconductor industry. During the development of a new manufacturing process line for a semiconductor device, tens of thousands of scanning electron microscopy (SEM) images are take ...