Award Data

Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

This project will develop a new scientific instrument optimized for the advanced characterization of near-infrared fluorescent nanoparticles that can exist as left- or right-handed structures (enantiomers). Single-walled carbon nanotubes (SWCNTs) are the leading current example of such nanomaterials. Applied NanoFluorescence, LLC (ANF) proposes a novel multi-mode chiroptical spectrometer that can ...

Alphacore will develop an Intermediate Frequency (IF) Conversion System for High-Bandwidth Multiplexed Sensors Arrays for Phase II of NIST's 2018 soliciation for Exploratory Measurement Science Topic 9.04.02.68.The proposing team has already successfully developed and evaluated a prototype board in Phase I.The goal in Phase II is therefore to achieve three primary objectives:1) Optimize the design ...

Phase I has proven that the current setup achieves better than 8mm spatial resolution for 2.2MeV prompt gammas. However, 1mm spatial resolution presents a significant challenge for the current setup due in part to limited timing resolution and count rate. A new analog ASIC will be developed to replace the current analog ASIC that will have better timing resolution and deliver higher count rates. I ...

Poor air quality represents a major public health risk, contributing to an estimated one of every eight deaths worldwide. Low-cost air quality sensors have developed rapidly over the last few years and offer the opportunity to make air quality monitoring widespread at an affordable price. However, low-cost sensors are currently unable to deliver accurate, reliable data due to a lack of understandi ...

Subsurface mooring beacons are used to provide notifications and assist in locating moored assets that have surfaced and are free drifting. Their nominal design is driven by the requirements for offshore use where they need to survive extreme depths and remote deployment, most often using satellite constellations for communication and geo-location. Existing beacons serve their purpose well, but th ...

In Phase I, we developed a prototype instrument for counting, sizing and identifying both non-toxic and toxic Harmful Algal Bloom (HAB) species. We did this by integrating three innovative technologies: High-throughput color, Light Field Imaging Flow Cytometry to acquire morphological information for each cell, Raman spectroscopy to acquire species-specific molecular information on pigments and tr ...

Marine life entanglement is one of the critical permitting issues that is currently constraining the growth of domestic offshore aquaculture. Synthetik Applied Technologies is proposing to develop a low-cost entanglement detection system for offshore aquaculture operators. The system will use a combination of near real-time satellite imagery, intelligent on-site cameras (both above and below the w ...

NIST developed risk management framework and guidelines that assist agencies to implement integrated, organization‐wide programs to manage information security risk, and further developed Cloud Security Architecture Tool (CSAT) to facilitate in this matter. However, NIST’s CSAT needs further improvement and implementation of new functions such that it can be commercialized as an Enterprise‐g ...

NOAA is pursuing sustained, in-situ sensing technology to support improved atmospheric modeling of the upper ocean boundary environment, including the air-sea interface, during turbulent storms. Improved atmospheric modeling in this critical region will lead to better forecasting and support NOAA's mandate to protect property and save lives. Small, unmanned aircraft, equipped with atmospheric sens ...