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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Active Disposable Cap for Endoscope Tip Stabilization and Complete Visualization and Dissection of Serrated Sessile Polyps
SBC: ACTUATED MEDICAL, INC. Topic: 300The SBIR Fast-track develops, tests, and commercializes the ‘Active Disposable Cap for Endoscope (ACE) Tip Stabilization and Complete Visualization and Dissection of Serrated Sessile Polyps.’ The disposable system includes a distal-connecting cap, allowing a clinician to manipulate tissue and perform targeted aspiration during complex polypectomies using proximal controls, without occupying th ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Advancement of antiviral inhibitors of chikungunya virus
SBC: VENATORX PHARMACEUTICALS INC Topic: NIAIDPROJECT SUMMARY Novel therapies for the treatment of chikungunya virus (CHIKV) infections are urgently needed to address the alarming spread of this pathogen across the Americas. We have identified three distinct series of potent, selective, and orally bioavailable inhibitors of CHIKV replication. In this Phase II renewal SBIR project, we will optimize these series of CHIKV inhibitors to Pre-Devel ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Advancing and calibrating anisotropic diffusion MR imaging brain connectome with Taxon brain network diffusion phantoms
SBC: Psychology Software Tools, Inc. Topic: 106There is a critical gap in the reliability of anisotropic diffusion magnetic resonance imaging (AdMRI). This gap can be filled by using a ground truth measurement capability that allows for the necessary parametric control of water filled geometries of tubes at the micron scale that can produce paths representative of the millions of axons across centimeters in brain tract trajectories. Diffusion ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Altering the injury microenvironment with a macrophage and Schwann Cell recruiting extracellular matrix-based hydrogel to improve laryngeal nerve injury recovery
SBC: Renerva, LLC Topic: NIDCDPROJECT SUMMARY ABSTRACT Vocal fold paralysisVFPoccurs when the recurrent laryngeal nerveRLNis injuredmost commonly during surgery of the neckBilateral injury to the RLN can result in potentially life threatening airway obstruction and the need for tracheostomyThe RLN can regenerate some of its axonsbut in many patients with paralysis some form of intervention is required to correct the airway obs ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
An acoustofluidic device for diagnosing preclinical Alzheimer's disease
SBC: Ascent Bio-Nano Technologies Inc Topic: NIAAbstract Alzheimer s diseaseADis a progressivedisabling neurodegenerative illness that affects an estimatedmillion people in the United States and approximatelyof the population over the age ofEarly symptoms of the disease include short term memory lossdifficulties with languageand mood swingshoweversymptoms gradually worsen over timeultimately leading to dementia and a loss of bodily functionsSig ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A New Drug for the Treatment of Traumatic Brain Injury
SBC: Azevan Pharmaceuticals Inc Topic: 105Project Summary AbstractTraumatic Brain InjuryTBIcontributes to a third of injury related deaths in the US and is among the leading causes of death and disability in people underand overRecent statistics show that TBI annually causesdeathshospital admissionscarries an average lifetime expense of $patientand an annual economic burden conservatively estimated at $billionThe lack of any approved drug ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A Novel Synthetic Vascular Graft Capable of Minimally Invasive Controlled Expansion for Vascular Reconstruction Model
SBC: PECA LABS INC Topic: NHLBIPROJECT SUMMARY In pediatric cardiovascular surgery, no commercially available vascular conduit is capable of growing with the patient following implantation. This inability to grow with the patient is particularly relevant for newborns and young children because additional surgeries are required to replace the implanted conduit. In order to address this issue, PECA Labs has developed a novel card ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Antibody Fragments to Improve HIV gp120 Protein Production
SBC: ABZYME THERAPEUTICS LLC Topic: NIAIDCamelid single domain antibody fragmentsVHHpossess a number of distinctive features including a small sizean elevated stabilityand an ability to recognize epitopes non accessible for conventional antibodiesBesides common research and immunotherapy applicationscamelid VHHs are also used as co crystallization chaperonesprotein aggregation controllers and enzyme activity tunersIn this proposalwe wish ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
An ultrasensitive virus identification method for acute respiratory virus infections using carbon nanotube arrays-integrated microdevice
SBC: CAPTIS DIAGNOSTICS Topic: NIAIDSUMMARY Acute respiratory tract infections are the leading cause of infectious related mortalitythe fifth leading cause of death overallIn particularrare unrecognized acute respiratory virusARVinfection outbreaks caused many human diseases of unknown etiologyparticularly in less developed countriesIf active ARV infection can be accurately detected and effectively vaccinated or treated with the rig ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A Rapid Non-Invasive Device for Monitoring Preeclampsia inHigh Risk Pregnancy
SBC: ACCEL DIAGNOSTICS, LLC Topic: NICHDProject Summary PreeclampsiaPEis a pregnancy specific life threatening disorder and one of the leading causes of maternal and fetal morbidity and mortalityIt is responsible for approximatelyof maternal deaths in the US and is the leading cause of intensive care unit admissions in theweeks following deliveryRates of severe PE have tripled sinceThe diagnosis of PE is complicated by heterogeneity in ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health