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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A2A receptor blockade for sepsis

    SBC: Purine Pharmaceuticals Inc.            Topic: NIAID

    SUMMARY Sepsis is a clinical syndrome that complicates severe infectionSepsis remains the leading cause of morbidity and mortality in critically ill patientsThere are no specific FDA approved medicines for the treatment of sepsisCurrent concepts of the pathophysiology of sepsis suggest that organ failure and mortality in sepsis are caused by inappropriate regulation of the immune systemThis manife ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A badge-like exposure device for occupational safety and epidemiological study

    SBC: TF HEALTH CORPORATION            Topic: R

    Abstract Chemical exposure poses a threat to the safety and health of each of us, especially those who work in certain industries, such as petroleum extraction and refinery facilities, mining industry, and fertilizer factories. Various sensing technologies have been developed over the past decades to address the need, but a low cost and accurate personal exposure device that can track multiple che ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. A Bedside Relational Agent to Improve Hematopoietic Cell Transplantation Outcomes in Cancer Patients

    SBC: care.coach corporation            Topic: 101

    Abstract Deliriuma major cause of fallscan occur in as many asof cancer patients undergoing stem cell transplantationresulting in up totimes greater chance of dyingDelirium risk can be mitigated and many other outcomes of stem cell transplants can be improved through behavioral interventions delivered at the bedside through conversationimageryand audioHowevertraditional means of delivering these i ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. A Better Mechanism for Controlled Nanopore Translocation

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: 172

    Project Summary Enabling high accuracy nanopore based strand sequencing has the potential to improve the understanding of long range genomic relationships and processes andbased on its accessibilityenable the associated clinical and diagnostic applicationsthe fastest growing sequencing sectorUnfortunatelyit is commonplace for nanopore sequencing error rates to exceedand higher accuracy is needed t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. A Biosynthetic Degradable Textile for Soft Tissue Reconstruction

    SBC: Deep Blue Medical Advances, Inc.            Topic: 300

    AbstractBiosynthetic or synthetic degradable hernia mesh is the fastest growing segment of the hernia mesh marketreaching$M in sales inwith Bard controllingof the US marketfollowed by GoreNovus Scientificand EthiconWhile biosynthetic mesh may be used in any type of hernia repairit is most commonly used in ventral hernia repair cases where there is an increased risk of bacterial infectionThe reason ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Ablation of the pathogenic RNA transcript associated with myotonic dystrophy, DM1

    SBC: Enzerna Biosciences LLC            Topic: NIAMS

    ABSTRACTMyotonic muscular dystrophyDMDis a genetic disorder characterized by muscle degeneration and weaknessIt is a common form of muscular dystrophy that generally begins in adulthoodUnfortunatelythere are no approved curative therapies for DMtreatments are largely palliativeThe more severe formmyotonic dystrophy typeDMis caused by theCTG n expansion in theUTR of the dystrophia myotonica protein ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Accelerate Adoption of Galaxy Pro in the Biomedical Research Marketplace

    SBC: GalaxyWorks LLC            Topic: NHGRI

    Project Summary Galactic Core LLC aims to develop a robust, scalable, and managed service for performing enterprise-grade biomedical data analysis. The service will be based on the popular open-source Galaxy application (​https://galaxyproject.org/​), offering unlimited data storage and compute capabilities with an extremely powerful, flexible, and collaborative environment for analyzing data. ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Accelerated Minimally Invasive Brain Clot Evacuation Using Guided Drug Delivery

    SBC: InseRT            Topic: 105

    SignificanceWe propose to extend and customize inseRT MRI s Real Time MR image guided surgical platformoriginally developed for cerebral biopsy and direct injection cancer therapiesto overcome shortcomings in CT guidance of a promising new thrombolytic therapy for intracerebral hemorrhageICHICH is a devastating injury creating stroke like outcomes inpeople in the USA each yearDamage from mechanica ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Accelerating Functional Maturation of Human Neurons for High-Throughput Screening

    SBC: BrainXell, Inc            Topic: 44

    Project Summary/AbstractNeurological and psychiatric disorders, including drug abuse and addiction, exert a devastating personal and economic toll on patients, families, caregivers, and society. This is in part due to our failure in developing effective medications, which in turn is due to the use of drug discovery platforms that are often not relevant to target diseases. The recent development of ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Accelerating Site-specific Characterization of Protein Therapeutics with Novel Machine Learning Methods

    SBC: MASSMATRIX, INC.            Topic: 400

    PROJECT SUMMARYABSTRACT TitleAccelerating Site specific Characterization of Protein Therapeutics with Novel Machine Learning Methods The project seeks to improve reliability and speed up the development of life saving and life enhancingprecisionprotein therapeutics and magnify the positive impact of biomedical research and education worldwideleading to a quantum leap in our understanding of the mo ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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