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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Bedside Relational Agent to Improve Hematopoietic Cell Transplantation Outcomes in Cancer Patients

    SBC: CARE.COACH CORPORATION            Topic: 101

    Abstract Deliriuma major cause of fallscan occur in as many asof cancer patients undergoing stem cell transplantationresulting in up totimes greater chance of dyingDelirium risk can be mitigated and many other outcomes of stem cell transplants can be improved through behavioral interventions delivered at the bedside through conversationimageryand audioHowevertraditional means of delivering these i ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A Better Mechanism for Controlled Nanopore Translocation

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: 172

    Project Summary Enabling high accuracy nanopore based strand sequencing has the potential to improve the understanding of long range genomic relationships and processes andbased on its accessibilityenable the associated clinical and diagnostic applicationsthe fastest growing sequencing sectorUnfortunatelyit is commonplace for nanopore sequencing error rates to exceedand higher accuracy is needed t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. A Biological Small Angle X-ray Scattering Station (BioSAXS) for the Compact Light

    SBC: LYNCEAN TECHNOLOGIES, INC.            Topic: NIGMS

    7. Project Summary/Abstract We propose to develop a Biological Small-angle X-ray Scattering (BioSAXS) station for the Compact Light Source, a powerful new generation of X-ray sources, which will enable biologists and biochemists to pursue state-of-the-artresearch in macromolecular structure studies in their own laboratories. The frontier of structural biology is the determination of large macromol ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Accelerating Wound Healing through RNAi

    SBC: Somagenics, Inc.            Topic: 300

    DESCRIPTION provided by applicant The growing populations of the elderly and those with type II diabetes are at high risk for developing chronic wounds that are slow to heal Effective therapeutics to promote wound healing could significantly improve the lives of these people Normal wound healing involves a coordinated cascade of events that are stimulated in part by the hypoxia that results f ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Accessible Balance and Falls Prevention Exercise Tool Across the Continuum of Car

    SBC: BLUE MARBLE REHAB INC            Topic: NIA

    DESCRIPTION (provided by applicant): Objective: This Phase 1 SBIR proposes to optimize the interface and interaction of a digital translation of Evidence Based Falls Prevention programs for use across the continuum of care and community living that affordseasy adoption, adherence and monitoring of falls prevention exercises for all stakeholders including those with limited technical experience. Pu ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Accurate and efficient density functional theory calculations of intermolecular interactions and conformational energies

    SBC: Q-CHEM INC            Topic: 300

    Abstract Biophysical properties can be computer-modeled using quantum mechanics (QM). While vastly more computationally costly than molecular mechanics (MM), QM methods are essential for bond-breaking and/or high accuracy. Indeed, QM methods have advanced with exciting, (and ongoing) improvements in the accuracy of density functional theory (DFT). These DFT improvements could open new applications ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A Cell-Penetrating Anthrax Antitoxin

    SBC: PLANET BIOTECHNOLOGY, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The goal of this research is to develop an economical, safe, effective therapy to reverse the activity of the catalytic component, LF, of the Bacillus anthracis toxin (lethal toxin), within the cytoplasm of the intoxicated cell. Success in achieving this goal will lead to better outcomes than currently seen with antibiotics or antitoxins like raxibacumab or PB ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. A Clinical Study of Latiglutenase as a Treatment for Symptom Reduction for Celiac Disease

    SBC: IMMUNOGENICS LLC            Topic: NIAID

    Project Summary AbstractThe goal of this work is to develop a therapeutic drug that will protect individuals with celiac diseaseCDfrom intestinal and symptomatic distress they suffer due to minute ingestion of gluten proteinCD is an autoimmune disorder affecting the small intestineafflicting aboutof the world s populationfor which there is no known cureCurrently the only therapeutic option to avoi ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. A Clinical Study of Latiglutenase as a Treatment for Type 1 Diabetics with Celiac Disease

    SBC: IMMUNOGENICS LLC            Topic: 300

    Project Summary The goal of this work is to evaluate the efficacy of a therapeutic agent for protecting individuals with TypediabetesT Dand celiac diseaseCDfrom intestinal and symptomatic distress they suffer due to minute ingestion of gluten proteinBoth T D and CD are lifelong autoimmune diseases whose management is anchored upon very restrictive and distinct dietsThe co morbidity of these two di ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A Combination Therapy Approach to Treating Drug Resistant Fungal Infections

    SBC: Amplyx Pharmaceuticals, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Despite the introduction of newer triazoles and echinocandins invasive fungal infections IFIandapos s including invasive candidiasis IC remain very difficult to treat with currently available antifungals The annual cost burden of treating nosocomial fungal infections exceeds $ billion a year in the United States alone Worldwide the annual incidence o ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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