Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP A MISSION AND AND ENGINE OIL ANALYSIS BY WHICH TRANSMISSION AND ENGINE WEAROUT CAN BE PREDICTED BY MEASURING OIL TEMPERATURE, CAPACITANCE AND PRESENCE OF HYDROCHLORIC ACID.

    SBC: Tillman & Comeau Associates            Topic: N/A

    THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP A MISSION AND AND ENGINE OIL ANALYSIS BY WHICH TRANSMISSION AND ENGINE WEAROUT CAN BE PREDICTED BY MEASURING OIL TEMPERATURE, CAPACITANCE AND PRESENCE OF HYDROCHLORIC ACID. THIS WILL BE ACCOMPLISHED BY TREATING THE OIL AS A LOSSY DIELECTRIC ACAND PLACING A TRANSDUCER IN THE OIL. BOTH CONDUCTANCE AND SUSCEPTANCE ON APPROPRIATE FREQUENCIES ARE MEASURED AND ...

    SBIR Phase I 1985 Department of Transportation
  2. Best Practices for IntelliDrive Enabled Mobile Application Development

    SBC: Mygistics Inc.            Topic: 102FH3

    The scope of this research initiative addresses what is best practice for delivering mobile applications while ensuring a safe, consistent experience given the differing communications standards, operating systems and hardware limitations of existing and prospective personal communications devices.  It is assumed the scope of this initiative is limited to exploration of applications for consumer devices only, not on-board OEM equipment/applications that may use a passenger's personal communications device to provide network connectivity.  However, the ability of a personal device

    SBIR Phase I 2011 Department of Transportation
  3. A MICROCOMPUTER EXPERT SYSTEM FOR INSTRUCTIONAL OBJECTIVES DEVELOPMENT

    SBC: Knowledge Software            Topic: N/A

    KNOWLEDGE SOFTWARE PROPOSES TO DETERMINE THE TECHNICAL FEASIBILITY OF USING A MICROCOMPUTER BASED EXPERT SYSTEM TO ASSIST EDUCATORS IN THE DEVELOPMENT OF INSTRUCTIONAL OBJECTIVES. THIS EFFORT SUPPORTS THE DEPARTMENT OF EDUCATION'S GOAL OF DEVELOPING METHODS TO SIMPLIFY AND IMPROVE COURSEWARE CREATION. WE PROPOSE TO DETERMINE FEASIBILITY BY DEVELOPING A MICROCOMPUTER BASED EXPERT SYSTEM. OUR PLAN I ...

    SBIR Phase I 1987 Department of Education
  4. ANTI-IDIOTYPIC MONOCLONAL ANTIBODY (AIMA) THERAPY HAS CURATIVE POTENTIAL FOR LOW-GRADE B-CELL LYMPHOMAS THROUGH IMMUNOLOGIC DOWN REGULATION OF THE MALIGNANT IDIOTYPIC CLONE AS WELL AS ANTIBODY-DEPENDENT CELL MEDIATED CYTOTOXICITY.

    SBC: Biomedical Research Laboratori            Topic: N/A

    ANTI-IDIOTYPIC MONOCLONAL ANTIBODY (AIMA) THERAPY HAS CURATIVE POTENTIAL FOR LOW-GRADE B-CELL LYMPHOMAS THROUGH IMMUNOLOGIC DOWN REGULATION OF THE MALIGNANT IDIOTYPIC CLONE AS WELL AS ANTIBODY-DEPENDENT CELL MEDIATED CYTOTOXICITY. PRODUCTION OF AIMA IS PATIENT-SPECIFIC AND LABOR INTENSIVE REQUIRING A MEDIAN OF 912 MONTHS UTILIZING THE CLASSICAL MURINE MYELOMA $ HUMAN B-CELL HYBRIDOMA APPROACH. THE ...

    SBIR Phase I 1985 Department of Health and Human Services
  5. AN EFFICIENT METHOD FOR GENERATING FULL-LENGTH CDNA

    SBC: Gold Biotechnology Inc            Topic: N/A

    GOLD BIOTECHNOLOGY, INC. IS STUDYING A NEW METHOD FOR GENERATING FULL-LENGTH CDNA. THIS METHOD SHOULD BE SIMPLE AND EFFICIENT AND THUS ALLOW CLONING OF BOTH RARE AND ABUNDANT MRNA. THIS METHOD IMPROVES UPON OTHER PROCEDURES IN THE FOLLOWING WAYS: (1) NO S1 NUCLEASE IS REQUIRED FOR CLONING CDNA INTO THE VECTOR, AND (2) TAILING OF CDNA IS UNNECESSARY FOR BOTH INSERTION OF THE CDNA INTO THE VECTOR AN ...

    SBIR Phase I 1987 Department of Health and Human Services
  6. AN ADVERSE REACTION TO A DRUG WHICH TAKES PLACE WHILE A PATIENT IS ON MEDICATION IS OFTEN IMPOSSIBLE TO DIAGNOSE ACCURATELY.

    SBC: Imbic Corpon            Topic: N/A

    AN ADVERSE REACTION TO A DRUG WHICH TAKES PLACE WHILE A PATIENT IS ON MEDICATION IS OFTEN IMPOSSIBLE TO DIAGNOSE ACCURATELY. THE NATURE OF THE UNDERLYING REACTION MAY HAVE AN IMMUNOLOGIC, TOXICOLOGIC, OR PHARMACOLOGIC BASIS. AMONG THE MOST NOTABLE IMMUNOLOGIC REACTIONS TO DRUGS ARE THOSE WHICH GIVE RISE TO ANTIBODIES THAT, IN THE PRESENCE OF DRUG, ATTACH TO BLOOD CELLS AND DESTROY THEM. THE MOST C ...

    SBIR Phase I 1985 Department of Health and Human Services
  7. BETA-ENDORPHIN (BE) IS A PEPTIDE COMPOSED OF THE 30 CARBOXYL-TERMINAL RESIDUES OF BETA-LIPOTROPIN (BLPH).

    SBC: Imbic Corpon            Topic: N/A

    BETA-ENDORPHIN (BE) IS A PEPTIDE COMPOSED OF THE 30 CARBOXYL-TERMINAL RESIDUES OF BETA-LIPOTROPIN (BLPH). IT HAS BEEN SHOWN TO BE A NATURALLY OCCURRING OPIATE, AS WELL AS TO POSSESS NONOPIATE RELATED BIOACTIVITY. CURRENT ASSAY TECHNIQUES ARE INADEQUATE DUE TO LACK OF IMMUNOLOGICAL SPECIFICITY RESULTING FROM CROSS-REACTING OF BE AND BLPH WITH THE SAME ANTIBODIES. A SEPARATION METHOD UTILIZING THE S ...

    SBIR Phase I 1985 Department of Health and Human Services
  8. THE FORMATION OF DNA-CARCINOGEN ADDUCTS IS AN IMPORTANT ENVIRONMENTAL FACTOR IN CARCINOGENESIS.

    SBC: Imbic Corpon            Topic: N/A

    THE FORMATION OF DNA-CARCINOGEN ADDUCTS IS AN IMPORTANT ENVIRONMENTAL FACTOR IN CARCINOGENESIS. RECENT TECHNIQUES FOR ISOLATION AND CHARACTERIZATION OF DEOXYNUCLEOSIDE-CARCINOGEN ADDUCTS AND SUBSEQUENT IMMUNOASSAY PROCEDURES CAN EFFECTIVELY DETECT THESE ADDUCTS FROM CELL LYSATES IN THE RANGE OF 1 ADDUCT/107 BASES. WE WILL USE OUR COMBINED TECHNICAL EXPERTISE IN THE AREAS OF NUCLEOTIDE/NUCLEOSIDE C ...

    SBIR Phase I 1985 Department of Health and Human Services
  9. ASSAY OF NUCLEOSIDES IN SMALL-CELL CARCINOMA OF THE LUNG

    SBC: Imbic Corpon            Topic: N/A

    SEVERAL INVESTIGATORS HAVE IMPLICATED MODIFIED RIBONUCLEOSIDES, PRESUMABLY MODIFICATION PRODUCTS FROM TRANSFER RIBONUCLEIC ACIDS (TRNAS), AS POTENTIAL BIOLOGICAL MARKERS FOR CANCER. ELEVATED LEVELS OF THESE MOLECULES HAVE BEEN QUANTITATED IN THE SERUM OR URINE OF CANCER PATIENTS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-ULTRAVIOLET (HPLC-UV) OR IMMUNOASSAY. IN THIS PROPOSAL, IMBIC CORPORATION WILL ...

    SBIR Phase I 1987 Department of Health and Human Services
  10. CHARACTERIZATION AND EXPRESSION OF CDNA CLONES ENCODING HUMAN PROTEASE NEXIN

    SBC: Invitron Corp            Topic: N/A

    PROTEASE NEXIN (PN), CDNA CLONES WERE ISOLATED FROM A HUMAN FIBROBLAST LIBRARY USING OLIGOMER PROBES DERIVED FROM THE N-TERMINAL AMINO ACID SEQUENCE OF THE PROTEIN. SEVERAL FULL-LENGTH CLONES WERE CHARACTERIZED AND FOUND TO BE APPROXIMATELY 2,100 BP LONG. THE PN CLONES CONTAINED A 1,260 BP OPEN-READING FRAME THAT DEFINES A 401-AMINO ACID PROTEIN WITH A CHARACTERISTIC LEADER PEPTIDE OF 19 AMINO ACI ...

    SBIR Phase I 1987 Department of Health and Human Services
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