Award Data

The Southeast XLerator Network proposes to create a networked and easily accessible regional technology transfer accelerator hub (“XLerator Hub” or “Hub”) to share best practices, disseminate education content, and offer products, services, facilities and other resources connected through both physical and online platforms for innovators and trainees in the Southeast IDeA states. Led by XL ...

Summary Cerebral malaria (CM) is a life-threatening clinical syndrome associated with malarial infection. Annually, malaria affects more than 200 million people and claims the lives of over 440,000 people worldwide, mostly African children. As a consequence of the high incidence of CM, it is often misdiagnosed for other pathologies with similar symptoms, leading to a high false positive rate for C ...

MZA proposes the development of the Integrated Directed Energy Aero-optical Surrogate (IDEAS) which consists of a 1/4th scale aircraft parent model and a laser pod architecture with modular beam director and supporting flow control configuration for transonic and supersonic aero-effects testing at the AEDC 16T wind tunnel. The laser pod model may be remotely articulated to point in arbitrary direc ...

Project Abstract Significance: Neurodegenerative and malignant diseases along with injury of the central nervous system (CNS) affect millions of Americans. These injuries and diseases are often devastating and difficult to treat, and effective drug delivery remains a significant challenge. Infusion of drugs into the brain parenchyma using convection-enhanced delivery (CED) allows direct treatment ...

As submarine threats from adversary countries continue to rise, the U.S. Navy must maintain and expand its anti-submarine warfare (ASW) capabilities. Warfighter readiness is the linchpin of the Navy’s ASW strategy, but the complexity of the ASW domain necessitates time-consuming training, and practical experiences to transfer those skills to the operational environment. Innovative training appro ...

Laser-based anti-aircraft missile countermeasure systems use precisely aimed lasers to thwart the attack of these deadly missiles. In a matter of seconds, these systems must detect and characterize the threat, acquire the target, achieve track lock on the target, and initiate engagement of the threat's seeker with an in-band laser. The survival of our Warfighters and their aircraft during this ext ...

Future battlefields employing directed energy technologies will require an electronic Battle Damage Indicator (eBDI) tool that can measure the radiated Radio Frequency (RF) emissions from a target before and after a High Power RF (HPRF) attack and determine if target electronics have been significantly disrupted. Based on the Phase I results, we propose to assemble, test, and demonstrate an Autono ...

Agilvax’s AX09 is an Immunotherapy for Triple-Negative Breast Cancer: Agilvax is developing cancer immunotherapies and vaccines with its proprietary virus-like-particle (VLP) platform technology. Agilvax’s lead product, AX09, is an immunotherapy for triple-negative breast cancer (TNBC) targeting cancer stem cells (CSC) that is designed for use in combination with existing and emerging therapie ...

Transparent Sky LLC (TSky) and UltraHiNet LLC propose algorithms systems for precision computation in real-time of 3D (RT3D) models using low size, weight, and power (SWaP) architectures. Results exploit the successful Phase I algorithm, Shell3D, that over 100 times faster than leading algorithms. Further work will: • Build and test a prototype system for UAV use. • Develop field-testable soft ...

PROJECT SUMMARY Lead contamination in drinking water is a pervasive health problem across the US. Children are especially vulnerable to lead poisoning, which can have permanent detrimental effects on brain development. Despite corrosion prevention measures taken by public water authorities, lead concentrations in drinking water are routinely elevated nationwide. The Environmental Protection Agency ...