Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. TOPIC #366- PHASE II SBIR CONTRACT- CLONOGENIC HIGH- THROUGHPUT ASSAY FOR SCREENING RADIATION MODULATION

    SBC: SuviCa, Inc.            Topic: NCI

    Clonogenic assays measure the ability of single cells to proliferate and form a colonyThis process approximates closely the regrowth and recurrence of tumors after treatment with radiation or chemotherapyproviding an assay to screen for drugs that block this processYetclonogenic assays are labor intensive and too cumbersome for high throughout screeningHTSof compound librariesHere we propose to de ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Innovative Optical System for Hemagglutination Assays

    SBC: INDEVR, INC.            Topic: NIAID

    PROJECT SUMMARY The Hemagglutination assay HA and Hemagglutination Inhibition HI assay are widely used methods for characterizing viruses bacteria and antibodies The World Health Organization recently recommended that HI remain the gold standard method for influenza seroepidemiology Although the HA and HI assays are applied worldwide they have the disadvantages of manual plate reading no ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Safety Studies for Clinical Trials of a Botanical Drug for Sickle Cell Disease

    SBC: INVENUX, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant New therapeutic agents are urgently needed for the treatment of sickle cell disease the worldandapos s most common genetic disease Our long term goal is to develop a botanical drug SCD for use in children and adults that slows or stops disease progression Sickle cell disease affects approximately people in the United States and millions worldw ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. High Resolution Magnetoencephalography using Atomic Magnetrodes

    SBC: QUSPIN INC.            Topic: 101

    DESCRIPTION provided by applicant We propose to develop a small fully integrated ultra sensitive commercial magnetometer that will merge the multi use and cost effective attributes of present EEG electrodes with the sensitivity of SQUID sensors Our device referred to as a magnetrode will combine reliable autonomous operation with straightforward multi channel integration for a robust MEG ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Advanced Micropatterned Wound Dressings for Enhanced Epithelialization

    SBC: Sharklet Technologies Inc.            Topic: NIAMS

    Summary Nearly million wounds are treated in U S emergency departments every year Skin wounds such as severe burns large trauma wounds or non healing chronic wounds that are too extensive or complex to close by natural healing are often reconstructed using autologous skin grafts Although autologous skin grafts are currently the gold standard in complex wound repair there are significant ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Enhancing Care of the Aged and Dying in Prisons

    SBC: KLEIN BUENDEL, INC            Topic: NIA

    The United States has the highest rate of incarceration in the world There are over state and federal prisons housing over million prisoners in the United States The demographics of the prison population are shifting Longer sentences and constrained options for early release compound this trend The older adult segment of prison populations has more than tripled since The health ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. In Situ Autovaccination against Solid Cancers with Intratumoral Hiltonol Poly ICLC A phase II Adaptive Multicenter Clinical Study

    SBC: Oncovir            Topic: 102

    DESCRIPTION provided by applicant Hiltonol poly ICLC is a stabilized dsRNA therapeutic viral mimic or andapos danger signalandapos that activates multiple elements of innate and adaptive immunity It is a standalone immunomodulator but when properly combined with antigen it generates a comprehensive Th weighted immune response best suited for antiviral and antitumor action This project ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. I Live Inspired Individually Tailored and Integrated Social Support Network for Tobacco Cessation

    SBC: Live Inspired, LLC            Topic: NIDA

    DESCRIPTION provided by applicant Smoking kills Americans annually exacerbates myriad diseases and costs billions in healthcare and productivity losses Numerous barriers exist to accessing traditional treatment e g costs traveling to and scheduling appointments other logistics Text messaging is an extremely popular communication method Over of all Americans use text m ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Developing a Small Peptide to Control Autoimmune Inflammation In Type 1 Diabetes

    SBC: Op-T-Mune, Inc            Topic: NIAID

    TypeDiabetesT Daffects an ever growing populationWhile this disease typically has been associated with juvenilesthe disease in adult populations is rapidly increasingThe defining clinical component is insulin losswhich occurs because of sustained inflammation in the isletsAt present there is no means to prevent or reverse insulin lossA major inflammatory pathway in T D that contributes to insulin ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Rapid Test to Assist Therapy in Neonatal Sepsis and Necrotizing Enterocolitis

    SBC: PROTHERA BIOLOGICS, LLC            Topic: R

    The primary goal of this proposed research is to develop a rapid point of care test that assesses the risk of neonatal sepsisNSand or necrotizing enterocolitisNECin infants based on Inter alpha inhibitor proteinsIAIPlevels in bloodThe test is expected to be simpleuser friendlyportable and suitable for use in the NICUNS and NEC are associated with high mortality and morbidityincluding adverse neuro ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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