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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Stable Glucagon for Treatment of Hyperinsulinism

    SBC: AMIDEBIO, LLC            Topic: 200

    In severe persistent hyperinsulinism (HI), repeated hypoglycemic episodes can ultimately lead to permanent seizure disorders, learning disabilities, cerebral palsy, blindness and even death. Clinical studies have demonstrated the effectiveness of both short-term and long-term treatment with glucagon for severe forms of HI and continuous subcutaneous administration of glucagon has been recommended ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Development of Serious Games and Physical Activities Instructed by a Social Robot for Improving the Well-being of Elderly Individuals with Alzheimer's Disease and Dementia

    SBC: Dream Face Technologies, LLC            Topic: NIA

    The objective of the proposed direct Phase-II SBIR project is to develop and study and the effectiveness of Serious Games and physical Activities played/performed by elderly people with Alzheimer’s disease and AD- related Dementias in interaction with Ryan, our successfully piloted Socially Assistive Robot (SAR). Ryan is an intelligent conversational life-like social robot, designed to improve t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. A Quality Control Program for Quantitative MRI DataAcquisition and Analysis in Multi-site Clinical Trials

    SBC: CALIBERMRI INC            Topic: 101

    Project Summary/Abstract There has been a shift to greater use of neadjuvant chemotherapy (NACT) in the clinical management of cancer. Often used in breast cancer to provide systemic treatment for possible or apparent metastatic disease, NACT also reduces the primary tumor size and facilitates breast conservation. Quantitative magnetic resonance imaging (qMRI) is an effective diagnostic for monito ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Acoustic Scaffold Bioreactor

    SBC: RESODYN CORPORATION            Topic: NHLBI

    This Small Business Innovation Research Phase II project will develop a commercially-viable device that uses micro-scale acoustic streaming (low frequency sound energy) to deliver mixing to the interior of three-dimensional (3D) scaffolds used for stem cell cultivation applications. The enabling advantage of low frequency sound energy is the ability to generate micro-scale mixing in and around sca ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Development of Ryan Companion Robot for Assisting Elderly People with Alzheimer's Disease

    SBC: Dream Face Technologies, LLC            Topic: NIA

    The objective of the proposed Fast-Track SBIR effort is to develop and commercialize the Ryan CompanionBot (hereafter, Ryan), an intelligent conversational life-like social robot, designed to improve the well-being and quality of life of older adults with early stage Alzheimerandapos;s disease (AD) and AD-Related Dementia (ADRD). According to the NIA, research reports estimate that as many as 5.1 ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Novel synthetic TLR4 agonists

    SBC: INIMMUNE CORP            Topic: NIAID

    Project SummaryThere are currently no approved vaccines for most emerging biological pathogens (Ebola, Chikungunya, MERS CoV, SARS, Zika), opportunistic infections (S. aureus, Candidiasis, adenovirus) or potential bioterrorism agents (Y. pestis, B. Pseudomallei, F. tularensis, Bunyaviridae, Flaviviridae), and therapeutic interventions such as antibiotics and antivirals are only effective for a sel ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Synoptic Approach to Harmonize Discrete Data Streams in Application Development

    SBC: IT WORKS! INC.            Topic: 180NH1

    Research conducted in Phase I identified a range of data sources providing vehicle related information to consumers shopping around or interested in knowing more about vehicles. Majority of the commercial data sources focused on vehicle features, new/used/CPO pricing, and vehicles listings. Such data sources lacked safety as their central focus, which is a concern for U.S. Department of Transporta ...

    SBIR Phase II 2019 Department of Transportation
  8. Rapid Test to Assist Therapy in Neonatal Sepsis and Necrotizing Enterocolitis

    SBC: PROTHERA BIOLOGICS, INC.            Topic: R

    The primary goal of this proposed research is to develop a rapid point-of-care test that assesses the risk of neonatal sepsis (NS) and/or necrotizing enterocolitis (NEC) in infants based on Inter-alpha inhibitor proteins (IAIP) levels in blood. The test is expected to be simple, user-friendly, portable and suitable for use in the NICU. NS and NEC are associated with high mortality and morbidity, i ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. NV103: Antibody Conjugated Nanoparticle for Ewing Sarcoma Targeted Therapy

    SBC: NANOVALENT PHARMACEUTICALS INC            Topic: 102

    This Phase II SBIR project seeks to demonstrate that novel, targetable nanoparticles can delivery therapeutic substances to human tumor cells and reduce tumor burden in cancer. The concept for these nanoparticles is based on the hybrid polymerized liposome nanoparticle (HPLN) that displays functional antibodies that target tumor cell surface markers. The therapeutic cargos are encapsulated cytotox ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Rapid, cost-effective whole genome screening tools for cryptic inversions and translocations

    SBC: KromaTiD, Inc.            Topic: 172

    ABSTRACT The proposed projectRapidcost effective whole genome screening tools for cryptic inversions and translocationswill advance a genomic approach to precision medicineenabling the discovery of diseasecausing genomic structural variations and reducing the risks associated with clinical gene editingStructural variations cause a wide range of diseases from rare diseases to cancersand can be prec ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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