Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Stable Glucagon for Treatment of Hyperinsulinism

    SBC: AMIDEBIO, LLC            Topic: 200

    In severe persistent hyperinsulinismHIrepeated hypoglycemic episodes can ultimately lead to permanent seizure disorderslearning disabilitiescerebral palsyblindness and even deathClinical studies have demonstrated the effectiveness of both short term and long term treatment with glucagon for severe forms of HI and continuous subcutaneous administration of glucagon has been recommended both because ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Development of Serious Games and Physical Activities Instructed by a Social Robot for Improving the Well-being of Elderly Individuals with Alzheimer's Disease and Dementia

    SBC: Dream Face Technologies, LLC            Topic: NIA

    The objective of the proposed direct Phase II SBIR project is to develop and study and the effectiveness of Serious Games and physical Activities played performed by elderly people with Alzheimer s disease and ADrelated Dementias in interaction with Ryanour successfully piloted Socially Assistive RobotSARRyan is an intelligent conversational life like social robotdesigned to improve the well being ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. A Quality Control Program for Quantitative MRI DataAcquisition and Analysis in Multi-site Clinical Trials

    SBC: QalibreMD, Inc.            Topic: 101

    Project Summary Abstract There has been a shift to greater use of neadjuvant chemotherapyNACTin the clinical management of cancerOften used in breast cancer to provide systemic treatment for possible or apparent metastatic diseaseNACT also reduces the primary tumor size and facilitates breast conservationQuantitative magnetic resonance imagingqMRIis an effective diagnostic for monitoring tumor reg ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Development of Ryan Companion Robot for Assisting Elderly People with Alzheimer's Disease

    SBC: Dream Face Technologies, LLC            Topic: NIA

    The objective of the proposed Fast Track SBIR effort is to develop and commercialize the Ryan CompanionBothereafterRyanan intelligent conversational life like social robotdesigned to improve the well being and quality of life of older adults with early stage Alzheimerandapos s diseaseADand AD Related DementiaADRDAccording to the NIAresearch reports estimate that as many asmillion Americans may hav ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Synoptic Approach to Harmonize Discrete Data Streams in Application Development

    SBC: It Works Inc            Topic: 180NH1

    Research conducted in Phase I identified a range of data sources providing vehicle related information to consumers shopping around or interested in knowing more about vehicles. Majority of the commercial data sources focused on vehicle features, new/used/CPO pricing, and vehicles listings. Such data sources lacked safety as their central focus, which is a concern for U.S. Department of Transporta ...

    SBIR Phase II 2019 Department of Transportation
  6. Rapid Test to Assist Therapy in Neonatal Sepsis and Necrotizing Enterocolitis

    SBC: PROTHERA BIOLOGICS, LLC            Topic: R

    The primary goal of this proposed research is to develop a rapid point of care test that assesses the risk of neonatal sepsisNSand or necrotizing enterocolitisNECin infants based on Inter alpha inhibitor proteinsIAIPlevels in bloodThe test is expected to be simpleuser friendlyportable and suitable for use in the NICUNS and NEC are associated with high mortality and morbidityincluding adverse neuro ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Rapid, cost-effective whole genome screening tools for cryptic inversions and translocations

    SBC: KromaTiD, Inc.            Topic: 172

    ABSTRACT The proposed projectRapidcost effective whole genome screening tools for cryptic inversions and translocationswill advance a genomic approach to precision medicineenabling the discovery of diseasecausing genomic structural variations and reducing the risks associated with clinical gene editingStructural variations cause a wide range of diseases from rare diseases to cancersand can be prec ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Point-of-Care Prognostic Tool for Sepsis

    SBC: Mbio Diagnostics, Inc.            Topic: 300

    Sepsis is a devastating cause of morbidity and mortality in intensive care unitsICUswith estimates of U Sincidence ranging fromtomillion cases annuallyThe heterogeneity of clinical presentationetiologypatient historyseverityetccreates a major challenge for patient management and has significantly complicated development of new therapiesalmost all of which have failed to show significant benefitBec ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Personal Mercury Monitor for Exposure Measurements

    SBC: First American Scientific Corporati            Topic: NIEHS

    Personal Mercury Monitor for Exposure Measurements Project Summary AbstractWorkers in the oil and natural gas industry are vulnerable to exposure to toxic mercuryHgvapor as a result of routine inspection and maintenance of equipment such as compressors and other process equipment that concentrate species of low volatility over timeExposure of workers to elemental mercury vapor is of concern in man ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A next generation spatial light modulator for mapping of neural networks

    SBC: Boulder Nonlinear Systems, Inc.            Topic: NIBIB

    Boulder Nonlinear Systems BNS and Prof Edward Boyden s Synthetic Neurobiology Group at the Massachusetts Institute of Technology MIT Media Lab propose to develop a new liquid crystal spatial light modulator SLM capable generating high resolution holograms to overcome the imaging gap that currently divides cellular level optogenetic techniques and whole brain techniques to improve function ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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