Award Data

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to develop an industry-ready service to improve public transportation for riders with disabilities, specifically visual impairments. The LookingBus technology helps drivers accommodate the needs of certain riders, while limiting distractions from their primary roles of driving safely. Indi ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be to address the lack of advanced maps of shallow water zones, or littoral zones, crucial to global ecology and economy. An estimated 70% of the world's littoral zone is not mapped to modern standards, and traditional methods of mapping these areas are prohibitively expensive and danger ...

This proposed Small Business Innovative Research (SBIR) Phase II project is to develop, prototype and commercialize a Green Rooftop Technology with superior building energy efficiency to significantly reduce energy consumption of our nation’s industrial and commercial buildings. Besides, this proposed technology can significantly extend the lifespan of current building rooftop materials to ...

The next generation Multifunctional Information Distribution System Joint Tactical Radio System (MIDS JTRS) is currently undergoing an upgrade to integrate new Tactical Targeting Network Technology (TTNT) capabilities. The high-power processors required generate more heat than previous shop replaceable units (SRUs). The upgraded MIDS JTRS radio terminal will generate up to approximately 30% higher ...

In severe persistent hyperinsulinism (HI), repeated hypoglycemic episodes can ultimately lead to permanent seizure disorders, learning disabilities, cerebral palsy, blindness and even death. Clinical studies have demonstrated the effectiveness of both short-term and long-term treatment with glucagon for severe forms of HI and continuous subcutaneous administration of glucagon has been recommended ...

This project will provide critical preclinical data for a novel therapeutic small molecule inhibitor of plasminogen activator inhibitor 1 (PAI-1) as a potential treatment for diffuse cutaneous systemic sclerosis with associated interstitial lung disease (dcSSc-ILD). SSc is a devastating disease of unknown etiology with no currently approved disease-modifying treatments; lung fibrosis (interstitial ...

PROJECT SUMMARY/ABSTRACT Approximately 6.3 million fractures occur in the United States each year, accounting for 16% of all musculoskeletal injuries and leading to well over 10 million hospital and physician offices visits. Up to 10% of fractures are recalcitrant and require surgical intervention for proper healing. The weakened bones in the growing geriatric population are contributing to the ri ...

PROJECT SUMMARY/ABSTRACT This project responds to the need identified by NIDCR to develop improved methods to detect and predict progression of dental caries (tooth decay) to improve human health. Worldwide, caries is the most common chronic disease affecting almost everyone. Dental disease is a major cause of economic and social loss and leads to complications including pain, tooth loss and even ...

The objective of the proposed direct Phase-II SBIR project is to develop and study and the effectiveness of Serious Games and physical Activities played/performed by elderly people with Alzheimer’s disease and AD- related Dementias in interaction with Ryan, our successfully piloted Socially Assistive Robot (SAR). Ryan is an intelligent conversational life-like social robot, designed to improve t ...

Project Summary/Abstract There has been a shift to greater use of neadjuvant chemotherapy (NACT) in the clinical management of cancer. Often used in breast cancer to provide systemic treatment for possible or apparent metastatic disease, NACT also reduces the primary tumor size and facilitates breast conservation. Quantitative magnetic resonance imaging (qMRI) is an effective diagnostic for monito ...