Award Data

Research conducted in Phase I identified a range of data sources providing vehicle related information to consumers shopping around or interested in knowing more about vehicles. Majority of the commercial data sources focused on vehicle features, new/used/CPO pricing, and vehicles listings. Such data sources lacked safety as their central focus, which is a concern for U.S. Department of Transporta ...

The primary goal of this proposed research is to develop a rapid point of care test that assesses the risk of neonatal sepsisNSand or necrotizing enterocolitisNECin infants based on Inter alpha inhibitor proteinsIAIPlevels in bloodThe test is expected to be simpleuser friendlyportable and suitable for use in the NICUNS and NEC are associated with high mortality and morbidityincluding adverse neuro ...

DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

DESCRIPTION provided by applicant Smoking kills Americans annually exacerbates myriad diseases and costs billions in healthcare and productivity losses Numerous barriers exist to accessing traditional treatment e g costs traveling to and scheduling appointments other logistics Text messaging is an extremely popular communication method Over of all Americans use text m ...

DESCRIPTION provided by applicant Hiltonol poly ICLC is a stabilized dsRNA therapeutic viral mimic or andapos danger signalandapos that activates multiple elements of innate and adaptive immunity It is a standalone immunomodulator but when properly combined with antigen it generates a comprehensive Th weighted immune response best suited for antiviral and antitumor action This project ...

There are two main objectives of the follow-on Phase II for Small Business Innovation Research Topic N08-199.First is to deliver a portable Splash Impact Measurement System (SIMS) with capablility of mapping the debris field surrounding an engagement event in broad ocean areas.This mapping will provide the precise location and time of all objects impacting the sea surface.The second objective is t ...

DESCRIPTION (provided by applicant): More than 10 million individuals in the U.S. are thought to suffer from diabetic neuropathies. Many serious medical problems stem from this condition, including degradation of the mechanical senses of touch and propri

DESCRIPTION (provided by applicant): Stroke survivors constitute one of the largest groups of patients receiving rehabilitation services in the United States. The inability of most stroke survivors to regain full sensorimotor function significantly imp

The BMDS is being developed as a fully integrated, layered defense capable of defending against all ranges of threats. A critical aspect of this development is an integrated approach to interceptor allocation. A model-based framework for optimizing multi-layer BMDS performance, developing interceptor firing doctrine, and providing for adaptive, real-time interceptor allocation was developed in P ...

DESCRIPTION (provided by applicant): The goal of the proposed research is to develop a method for significantly improving the performance of sequencing by hybridization (SBH), thus decreasing the cost and increasing the speed of sequencing DNA. If succ