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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. DNA HYBRIDIZATION IN THE DIAGNOSIS OF INFECTIOUS DISEASE

    SBC: Diagnostic Hybrids Inc.            Topic: N/A

    DNA HYBRIDIZATION PROBES SPECIFIC FOR COMMON PATHOGENIC BACTERIA HAVE BEEN DEVELOPED. THE LONG TERM OBJECTIVE OF THIS RESEARCH IS THE PERFECTION OF SIMPLE PROTOCOLS AND A KIT USING DNA HYBRIDIZATION PROBES FOR THE DETECTION AND IDENTIFICATION OF PATHOGENS IN CLINICAL SPECIMENS. THE SPECIFIC AIM OF THIS PROPOSAL IS TO ASSESS THE FEASABILITY OF THIS APPROACH TO PATHOGEN IDENTIFICATION IN CLINICAL SP ...

    SBIR Phase II 1985 Department of Health and Human Services
  2. RESEARCH RELATED TO DEVELOPING A VISUAL TESTING DEVICE

    SBC: Q-t Products Inc.            Topic: N/A

    QUALITATIVE ADVANCES IN COMPUTER TECHNOLOGY HAVE LEVELED OFF SUFFICIENTLY TO JUSTIFY THE DEVELOPMENT OF A MULTI-USER, MULTI-FUNCTION, COMPREHENSIVE VISUAL TESTING INSTRUMENT FOR OPHTHALMOLOGISTS, VISUAL SCIENTISTS, AND OPTOMETRISTS. SUCH A SYSTEM COULD BE DEVELOPED WITH RELATIVE EASE WERE IT NOT FOR THE INDUSTRY STANDARD REFRESH RATE FOR GENERATING VIDEO IMAGES. UNFORTUNATELY, 60 HZ IS TOO SLOW FO ...

    SBIR Phase II 1985 Department of Health and Human Services
  3. COMPUTERIZED LIFE SKILLS AID FOR LD STUDENTS

    SBC: Athena Group/social Technology            Topic: N/A

    THIS PROPOSAL CONCERNS DEVELOPMENT OF AN INTERACTIVE, MICROCOMPUTER/VIDEODISC TOOL FOR TEACHING LIFE SKILLS TO LEARNING DISABLED HIGH SCHOOL STUDENTS. WE HAVE TERMED IT A LIFE SKILLS SYSTEM (LSS), AN ATTEMPT TO REMEDY PRESENT DAY SECONDARY SCHOOL CURRICULUM DEFICIENCIES IN TRAINING LD STUDENTS TO FUNCTION INDEPENDENTLY. THE LSS IS BASED ON FUNCTIONAL CONTEXT TRAINING, AND THUS IS A DISTINCT DEPART ...

    SBIR Phase II 1985 Department of Health and Human Services
  4. DEVELOPING/MARKETING AN ASTHMA SELF-MANAGEMENT PROGRAM

    SBC: Allergy And Asthma Consultants            Topic: N/A

    THE PURPOSE OF THIS STUDY IS THREEFOLD: PART I WILL LAST APPROXIMATELY THREE MONTHS; THE GOAL OF THIS SEGMENT WILL BE TO DEVELOP ALL COMPONENTS REQUIRED FOR A SELF-MANAGEMENT PROGRAM FOR ALL ASTHMATIC PATIENTS. THIS WILL ENTAIL, IN PART, REFINING AND VIDEOTAPING PORTIONS OF A PROGRAM WITH PROVEN EFFICIENCY, WHEEZERS ANONYMOUS. IN ADDITION, RELIABILITY AND VALIDITY OF PAPER-AND-PENCIL INSTRUMENTS U ...

    SBIR Phase II 1987 Department of Health and Human Services
  5. DEVELOPMENT OF IMPROVED TECHNIQUES FOR THE CLONING OF HUMAN

    SBC: Hipple Cancer Research            Topic: N/A

    THE DEVELOPMENT OF HUMAN TUMOR COLONY FORMING ASSAYS (HTCFA) HAS OPENED NEW POSSIBILITIES FOR BASIC AND CLINICAL CANCER RESEARCH. HOWEVER, THE PERFORMANCE OF THE DOUBLE-LAYER AGAR TECHNIQUE CURRENTLY USED BY THE MAJORITY OF INVESTIGATORS HAS BEEN GENERALLY LOW. IN THIS CONTRACT, WE PROPOSE THE FURTHER DEVELOPMENT OF AN ALTERNATIVE TECHNIQUE OF TUMOR CELL CLONING USING GLASS CAPILLARY TUBES INSTEAD ...

    SBIR Phase II 1987 Department of Health and Human Services
  6. IN VITRO ANTINEOPLASTIC DRUG TOXICOLOGY CHARACTERIZATION

    SBC: Hipple Cancer Research            Topic: N/A

    AMONG THE MAJOR DOSE-LIMITING TOXICITIES OF CURRENTLY USED ANTICANCER DRUGS ARE THOSE AFFECTING THE BONE MARROW, CARDIOVASCULAR SYSTEM, LUNGS, GASTROINTESTINAL TRACT AND THE NERVOUS SYSTEM. HOWEVER, HEMATOTOXICITIES CONSTITUTE THE MOST COMMON AND OFTEN MOST SIGNIFICANT SIDE EFFECT OF THE MAJORITY OF AGENTS. WE PROPOSE THE FURTHER DEVELOPMENT AND CHARACTERIZATION OF IN VITRO SYSTEMS FOR HUMAN MYELO ...

    SBIR Phase II 1987 Department of Health and Human Services
  7. IDENTIFICATION OF INFANTS AT RISK FOR MENTAL RETARDATION

    SBC: Infantest Corp.            Topic: N/A

    ADVANCES IN MEDICAL CARE HAVE ALLOWED A GREATER NUMBER OF NEONATES TO SURVIVE. THE RESULT HAS BEEN AN INCREASE IN THE NUMBER OF INFANTS AT RISK FOR LATER INTELLECTUAL RETARDATION. HAPPILY, 80 TO 90% OF HIGH-RISK INFANTS ARE INTELLECTUALLY NORMAL LATER IN LIFE. UNFORTUNATELY, NO VALID SCREENING DEVICE FOR DIFFERENTIATING INFANTS WHO WILL LATER BE INTELLECTUALLY NORMAL FROM THOSE WHO WILL BE RETARDE ...

    SBIR Phase II 1987 Department of Health and Human Services
  8. PURIFICATION OF MARINE OIL-DERIVED POLYUNSATURATES

    SBC: Ocean Organics Inc.            Topic: N/A

    THE SPECIFIC AIM OF THIS PROJECT IS TO DEVELOP TECHNOLOGIC- ALLY EFFICIENT AND COST-EFFECTIVE METHODS FOR THE SEPARATIONAND PURIFICATION OF MULTIGRAM QUANTITIES OF HIGH POLYUN- SATURATES (E.G., EICOSAPNOIC ACID, EPA, C20:5W3; DOCOSAHEXAENOIC ACID, DHA, C22:6W3; AND ESTERS) FROM MARINE/FISH OILS, WITH THE LONG-TERM OBJECTIVE OF MAKING THESE AND POSSIBLY OTHER HIGH POLYUNSATURATES AVAILABLE FOR A WA ...

    SBIR Phase II 1987 Department of Health and Human Services
  9. LIPID INCORPORATED SERUM-FREE MEDIUM

    SBC: Oncology Laboratorytory, In            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS PROJECT IS TO DESIGN A SERUM-FREE CHEMICALLY DEFINED MEDIUM FOR OPTIMUM GROWTH OF MAMMALIAN CELLS IN VITRO. THE SPECIFIC AIM OF THIS PROPOSAL IS TO SOLUBILIZE, BY MEANS OTHER THAN THE USE OF CARRIER PROTEINS, FATTY ACIDS, ALPHA-LIPOIC ACID, FAT-SOLUBLE VITAMINS, AND CHOLESTEROL IN AN EXISTENT SERUM-FREE MEDIUM, CHEE'S ESSENTIAL MEDIUM (CEM). BESIDES HORMONES, GROWTH ...

    SBIR Phase II 1987 Department of Health and Human Services
  10. ACCESSORY APARTMENTS-DEVELOPING A PRIVATE PARTNERSHIP TO MARKET THE CONCEPT AND COUNSEL THE HOMEOWNER

    SBC: Patrick H Hare Planning & Des            Topic: N/A

    ACCESSORY APARTMENTS BENEFIT OLDER HOMEOWNERS. THEY CAN PROVIDE INCOME, SECURITY, COMPANIONSHIP, AND A SOURCE OF SERVICES IN RETURN FOR RENT REDUCTIONS. THEY ALSO CREATE INEXPENSIVE RENTAL HOUSING, AND, BECAUSE OF THE BENEFITS LISTED ABOVE, A MEANS TO HELP OLDER HOMEOWNERS AGE IN PLACE.IN CONTRAST, INSTALLATION OF ACCESSORY APARTMENTS IS RARELY SEEN AS A WAY FOR BUSINESS PEOPLE TO MAKE MONEY. AS A ...

    SBIR Phase II 1987 Department of Health and Human Services
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