Award Data

THIS PHASE I PROGRAM ADDRESSES THE TECHNOLOGICAL AND ECONOMIC FEASIBILITY OF DEVELOPING A HIGH-SPEED DENTAL HANDPIECE USING A RADIAL INFLOW TURBINE OPERATING IN GAS (AIR) BEARINGS. RECENT TECHNOLOGICAL DEVELOPMENTS IN THE MINIATURIZATION OF GAS BEARINGS AND TURBINES INDICATE THAT FASTER SPEEDS AND SMALLER SIZES ARE POSSIBLE. THESE IMPROVEMENTS OFFER SEVERAL BENEFITS, INCLUDING REDUCED BURR SIZE, I ...

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WITH THE ADVENT OF MONOCLONAL ANTIBODY TECHNOLOGY, IT HAS BECOME CLEAR THAT THERE IS A GROWING NEED TO PRODUCE HUMAN CELLS AND CELL PRODUCTS IN LARGER QUANTITIES FOR THE TREATMENT OF VARIOUS IMMUNOLOGIC, INFECTIOUS, AND NEOPLASTICDISEASES. VERAX CORPORATION HAS DEVELOPED A NOVEL SYSTEM FOR THE MASS CULTURE OF MURINE HYBRIDOMA CELLS, AS WELL AS SEVERAL SERUM-FREE MEDIA. IT IS PROPOSED TO EXTEND DEV ...

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THE GOAL OF THIS PROJECT IS TO DESIGN A VISUAL/AUDIO SYSTEM THAT WILL ENHANCE THE ABILITY OF THE AGED, INFIRM AND BEDRIDDEN TO RECEIVE VISUAL AND AUDIO INFORMATION. THE PROJECT WILL INVESTIGATE THE USE OF A KINOFORM LENS AS AN ELEMENT OF A HOMECARE PRODUCT FOR THE VISUALLY HANDICAPPED. THE USE OF THE KINOFORM LENS TO OVERCOME THE EFFECTS IF DEGENERATIVE VISUAL PROBLEMS WILL ALSO BE INVESTIGATED. T ...

A NOVEL CLASS OF MATERIAL HAS BEEN DISCOVERED THAT EXHIBITS NON-MAGNETIC BEHAVIOR IN ITS NATIVE (SUB 50A) STATE, BUT WHEN ASSEMBLED INTO CLUSTERS OF ABOVE 500A IN DIAMETER EXHIBITS SUPERPARAMAGNETIC BEHAVIOR. MATERIALS OF THIS TYPE CAN BE PREPARED AS BIODEGRADABLE 500A CLUSTERS, INJECTED INTO PATIENTS AND USED AS SAFE, NON-TOXIC, DEGRADABLE MRI CONTRAST AGENTS. A RESEARCH PROGRAM WILL UTILIZE THES ...

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Our goal is to identify novel parasite derived immunomodulatory tolerogenic adjuvants that can suppress pro inflammatory and autoimmune disease statessuch as typediabeteswhich has no disease modifying treatmentParasitic helminths establish chronic infection by modulating host innate and adaptive immune responsesdown regulating T effector cellsstimulating Thand or inducing regulatory B and T cellsS ...

More and more newborn babies are exposed to opioids in the womb and experience withdrawal symptoms at birthProperly diagnosing and treating patients is difficultnot all newborns that are at risk actually experience these withdrawal symptoms and require treatmentDiagnosis is affected by the experiencetrainingand opinion of the clinical staffBecause of the subjective nature of these assessmentssome ...

High throughput screeningHTShas emerged as a leading method of drug discovery and development in the pharmaceutical industryacademiaand at the NIH National Center for Advancing Translational SciencesNCATSHTS relies on the ability to rapidly screen tens of thousands of compounds to identify the most promising drugs and their dose response curvesHTS isof necessityhighly automated and demands mechani ...