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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. EMERGENCY VENTILATORY SUPPORT DEVICES BASED ON H202

    SBC: Abel Company            Topic: N/A

    THERE IS A CLEAR NEED FOR AN EMERGENCY OXYGEN DELIVERY SYSTEM THAT COMBINES RELIABILITY, LONG-TERM STORAGE CAPABILITY, VARIABLE AND CONTROLLABLE FLOW RATE, SMALL SIZE,SAFETY, AND SIMPLICITY OF USE. OF THE AVAILABLE OXYGEN STORAGE MEDIA, CHEMICAL SYSTEMS OFFER A REASONABLE LIKELI- HOOD OF ACHIEVING SUCH A SYSTEM. THIS PROJECT WILL INVESTIGATE THE FEASIBILITY OF USING LOW-COST HYDROGEN PEROXIDE AS T ...

    SBIR Phase II 1987 Department of Health and Human Services
  2. OXYGEN GENERATOR FOR AMBULATORY COPD PATIENTS

    SBC: Abel Company            Topic: N/A

    THE SPECIFIC GOAL OF THIS RESEARCH IS THE DEVELOPMENT OF A PORTABLE OXYGEN SOURCE SUITABLE FOR USE IN PROVIDING SUPPLE-MENTAL OXYGEN TO INDIVIDUALS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) RESULTING FROM CHRONIC BRONCHIOLI- TIS, PULMONARY EMPHYSEMA, ASTHMA, OR CHRONIC BRONCHITIS. THE CONCEPT IS BASED ON THE USE OF A COMMON, LOW-COST, HOUSEHOLD CHEMICAL THAT GENERATES OXYGEN WHEN WATER PLU ...

    SBIR Phase II 1987 Department of Health and Human Services
  3. DEVELOPMENT AND TESTING OF LAMINAR FLOW ISOLATORS FOR RODENT COLONIES

    SBC: Abel Company            Topic: N/A

    THE SPECIFIC AIM OF THIS STUDY IS TO DESIGN AND EVALUATE THEUSE OF HEPA-FILTERED, LAMINAR FLOW ISOLATION SYSTEMS AS SUBSTITUTES FOR PRESENT BARRIER SYSTEMS IN GERM-FREE AND GNOTOBIOTIC RESEARCH USING RODENTS AND OTHER SMALL ANIMALS.

    SBIR Phase I 1987 Department of Health and Human Services
  4. IN VIVO TOTAL BODY LEAD ANALYSIS BY X-RAY FLUORESCENCE

    SBC: ABIOMED, INC.            Topic: N/A

    THERE ARE AN ESTIMATED 600,000 CHILDREN UNDER SIX YEARS OLD WITH ELEVATED BLOOD LEAD LEVELS AND ONLY 5,000 PER YEAR UNDERGOING TREATMENT; AS YET, NO TECHNIQUE IS AVAILABLE TO MEASURE TOTAL BODY LEAD BURDEN. THIS PROPOSAL DESCRIBES A TECHNIQUE WHICH USES X-RAY FLUORESCENCE IN A TRANSMISSION GEOMETRY TO MEASURE THE TOTAL BODY-BURDEN OF LEAD, IN VIVO, NONINVASIVELY. A SYSTEM USING A GOLD CALIBRATION ...

    SBIR Phase II 1987 Department of Health and Human Services
  5. STIMULUS PAIRS IN 3D AUDITORY BRAINSTEM RESPONSE

    SBC: ABRATECH CORPORATION            Topic: N/A

    THE GOAL OF THIS RESEARCH IS TO DETERMINE THE FEASIBILITY OF COMBINING THREE-CHANNEL RECORDING OF THE AUDITORY BRAINSTEM RESPONSE (ABR) WITH A STIMULUS-PAIRS TECHNIQUE SO AS TO MEASURE THE DECREMENT IN RESPONSE THAT OCCURS IN THE RELATIVE REFRACTORY PERIOD (RRP). THIS METHOD WILL PERMIT DETECTION OF ANY ABNORMALITIES THAT AFFECT THE RRP, AS THE PARAMETERS CAN BE ADJUSTED SO THAT THERE IS DECREMENT ...

    SBIR Phase I 1987 Department of Health and Human Services
  6. DESIGN OF A PROTON MEDICAL ACCELERATOR

    SBC: Acctek Associates, Inc.            Topic: N/A

    THE LONG-RANGE GOAL OF THIS PROGRAM IS THE DEVELOPMENT AND COMMERCIALIZATION OF PROTON ACCELERATORS SUITABLE FOR RADIATION THERAPY OF CANCER IN HOSPITAL OR CLINICAL SETTINGS. FOR THIS PURPOSE THE ACCELERATOR SHOULD HAVE AN ENERGY UP TO 250 MEV, AND MUST BE SIMPLE, RELIABLE, AND INEXPENSIVE COMPARED TO EXISTING ACCELERATORS FOR PHYSICS APPLICATIONS. IN ADDITION, WITH SUFFICIENT INNOVATION, IT COULD ...

    SBIR Phase II 1987 Department of Health and Human Services
  7. A SELF-REGULATING PUMP CHAMBER FOR STANDARD ROLLER PUMPS

    SBC: Adam Spence Corpon            Topic: N/A

    THE ROLLER PUMP, USED TO PUMP BLOOD FLOW DURING CARDIOPULMONARY BYPASS AND TO PROVIDE LONG-TERM CIRCULATORY SUPPORT, IS A CONSTANT-BLOOD-FLOW DEVICE. IT MAINTAINS CONSTANT FLOW INDEPENTLY OF THE CLINICALLY EXPECTED CHANGES IN INLET PRESSURES. A DECREASE IN BLOOD SUPPLY TO THE INLET OF THE PUMP WITHOUT A CONCOMITANT DECREASE IN PUMP SPEED CAN CAUSE EXCESSIVE SUCTION LEADING TO AIR EMBOLISM, THROMBO ...

    SBIR Phase I 1987 Department of Health and Human Services
  8. EFFECTS OF A HEALTH AND WELL-BEING PROGRAM ON THE ELDERLY

    SBC: Adults Health & Dev Programs            Topic: N/A

    THE HYPOTHESIS TO BE TESTED IS THAT A 7-DAY, HEALTH AND WELL-BEING CAMP (ADULTS HEALTH & DEVELOPMENT PROGRAMS, INC.'S CAMP AHDP) FOR THE "WELL" ELDERLY WILL SIGNIFICANTLY IMPROVE OBJECTIVE AND SUBJECTIVE HEALTH, SYMPTOMATOLOGY, SUBJECTIVE WELL-BEING, AND ASPECTS OF PHYSICAL FITNESS. THE APPROXIMATELY 80 PARTICIPANTS WILL BE INDEPENDENTLY LIVING, RELATIVELY HEALTHY ADULTS BETWEEN AGES 50 TO 90 YEAR ...

    SBIR Phase I 1987 Department of Health and Human Services
  9. MEASUREMENT OF INTERLEUKIN-2 AND INTERLEUKIN-2 RECEPTOR BY ELISA

    SBC: Advanced Allergy Res Ctrs Inc            Topic: N/A

    DURING THE PAST 20 YEARS, DIFFERENT BIOLOGICAL ACTIVITIES HAVE BEEN DESCRIBED FOR LYMPHOKINES PRODUCED BY ACTIVATED LEUKOCYTES. INTERLEUKIN-1 (IL-1) IS A FACTOR PRODUCED BY ACTIVATED MONONUCLEAR PHAGOCYTES AND IS ESSENTIAL FOR SUPPORTING BOTH T-CELL AND B-CELL RESPONSES. ACTIVATED T CELLS PRODUCE INTERLEUKIN-2 (IL-2), A FACTOR NECESSARY FOR T-CELL PROLIFERATION. THIS SOLUBLE FACTOR EXERTS ITS BIOL ...

    SBIR Phase I 1987 Department of Health and Human Services
  10. IONTOPHORETIC CATHETER RESEARCH

    SBC: Advanced Clinical Products Inc            Topic: N/A

    THE URINARY TRACT IS A MAJOR SITE OF NOSOCOMIAL INFECTIONS. THE LEADING CAUSE OF THESE INFECTIONS IS URINARY CATHETERIZATION, WHICH IN TURN IS THE MOST COMMON PREDISPOSING FACTOR FOR FATAL GRAM-NEGATIVE SEPSIS IN HOSPITALS. THE LONG-TERM OBJECTIVE OF IONTOPHORETIC CATHETER RESEARCH IS TO DEVELOP A DEVICE TO PREVENT CATHETER-RELATED URINARY TRACT INFECTIONS. THE ULTIMATE CONFIGURATION ENVISIONED CO ...

    SBIR Phase I 1987 Department of Health and Human Services

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