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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Completion of IND-package for a novel, non-narcotic painkiller

    SBC: BLUE THERAPEUTICS, INC.            Topic: NIDA

    Project Summary Opioids like morphine and hydrocodone are generally the most effective therapeutics for treatment of moderate to severe pain. However, their use is limited by serious side effects - tolerance, constipation, respiratory depression, physical dependence and high addictive potential. The frequency of clinical pain, coupled with a lack of alternative therapeutic options has led to a nat ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. IGF::OT::IGF TOPIC 378: SYMPTOMATIC TOXICITY MOBILE MONITOR (SYMPTMM)

    SBC: VIVONICS INC            Topic: NCI

    The goal of this NIH Phase I SBIR proposal is to develop and validate a new method to monitor the symptomatic toxicities and health related quality of life of cancer patients who are undergoing and have undergone radiation therapy during the course of their treatmentThe proposal is built around expertise in mobile application developmentVivonics Incand radiation oncologyDrTJ Fitzgerald of the Univ ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. IGF::OT::IGF SBIR TOPIC 379: DIGIBIOMARC: DIGITAL BIOMARKERS FOR CLINICAL IMPACT- MOONSHOT PROJECT(FAST TRACK)

    SBC: Medable Inc.            Topic: NCI

    The overall objective of this Fast Track SBIR contract project is to develop DigiBioMarCTMDigital BioMarkers for Clinical Impacta scalable and flexible cloud based platform to capture and analyze wearableimplantableor external device dataThis platform also provides an informatics tool for automated data aggregationintegrationand machine learning algorithmsIt is based on the scalable user centered ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. TOPIC 372: DEVELOPMENT AND VALIDATION OF CANINE SCFVS FOR PRE-CLINICAL DEVELOPMENT OF TARGETED THERAPEUTICS

    SBC: Vetigenics LLC            Topic: NCI

    The goal of this SBIR is to provide proof of concept of Vetigenicscanine derived scFv phage display platform for rapidcost effective production of highly versatilecanine derived scFvsscFvs against CDCDand CTLAthree high valueimmunological molecules being targeted by antibody based strategies in human cancer immunotherapywill be isolatedSelected scFvs will be sequenced and binding affinities determ ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Structure-based discovery of dopamine D1 receptor selective small molecule ligands

    SBC: CONFOMETRX, INC.            Topic: 101

    Dopamine receptors are a family of G protein-coupled receptors (GPCRs), and can be further divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) subfamilies. In this proposal, we focus on D1 receptor, which is widely expressed in brain at high levels. Modulation of D1 activity is implicated in the treatment of many psychiatric and neurological disorders, such as schizophrenia, attention def ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Rapid and Simple Paper Strip Test for the Multiplexed Detection of Gastrointestinal Pathogens at the Point-of-Need

    SBC: Godx Inc.            Topic: 950

    PROJECT SUMMARY GoDx, Inc. has been developing a prototype multiplexed paper strip device for the detection of the DNA and RNA of gastrointestinal pathogens at the point-of-need in andlt; 30 minutes with funding from the NCATS SBIR parent grant TR 001912. We have used the same platform technology we are developing in the parent grant to develop a rapid (andlt;30 minute), low-cost and instrument-fr ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Continuous Monitoring of Natural Gas Infrastructure for Increased Community Resilience using Voltammetric Sensors

    SBC: FULLMOON SENSORS, INC.            Topic: None

    Fullmoon has the first chip-level sensors capable of identifying and quantifying molecules in the air. At the core of our technology are printed voltammetric sensors, which are operated using cyclic voltammetry, an electrochemical technique that probes for the redox potential, a unique signature of molecules. We have demonstrated this sensing principle for the detection of carbon monoxide and meth ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  8. Developing Commercial Quantum Resistance Standard Based on Epitaxial Graphene

    SBC: GRAPHENE WAVES, LLC            Topic: None

    Graphene Waves proposes to develop a quantum Hall resistance (QHR) standard based on graphene that can be deployed for general electrical calibration in industries. Current QHR standard is based on GaAs/AlGaAs heterostructure and requires expensive liquid helium to operate. The continuous increase in price and unstable supply chain of liquid helium limit the QHR standard to be only affordable by t ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  9. A Portable Vibrio Cholerae Concentrator for Sensitive Pathogen Detection in Water

    SBC: OMNIVIS INC            Topic: None

    This SBIR Phase I project proposes to develop an easy to use, inexpensive, and portable bacterial concentrator to enable more sensitive cholera pathogen (Vibrio cholerae) detection. Cholera affects communities across 41 countries, including Mozambique in 2019 after Cyclone Idai and Yemen in 2017. Current methods used to detect the cholera pathogen in water involves a 3 to 5-day procedure due to th ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  10. Laser Particle Separation

    SBC: Opthos Instrument Company, LLC            Topic: None

    Parman Tech is dedicated to commercializing a NIST technology for sorting nano-particles. This technology uses the force of light to gently guide particles along different paths depending on the size of makeup of each particle.

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
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