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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. SYNTHESIS OF HIGH MOLECULAR WEIGHT IRON CHELATORS

    SBC: Biomedical Frontiers, Inc.            Topic: N/A

    IN CHEMICAL AND BIOLOGICAL SYSTEMS, IRON IS BOTH UBIQUITOUS AND HIGHLY REACTIVE. IN A VARIETY OF CIRCUMSTANCES, THERE IS GREAT NEED FOR NEW APPROACHES TO THE REMOVAL OF IRON OR THE CONTROL OF ITS REACTIVITY. BIOMEDICAL FRONTIERS HAS PRODUCED A SERIES OF HIGH MOLECULAR WEIGHT IRON CHELATORS BASED ON DERIVATION OF A NUMBER OF SUBSTRATES WITH DEFER- OXAMINE B. THIS CHELATOR HAS AN EXTREMELY HIGH AFFI ...

    SBIR Phase II 1987 Department of Health and Human Services
  2. IMPROVED BIOCOMPATIBILITY OF INTRAOCULAR LENSES

    SBC: SURMODICS, INC.            Topic: N/A

    INTRAOCULAR LENS IMPLANTS HAVE RETURNED VISION TO MANY CATARACT PATIENTS. THESE IMPLANTS PROVIDE VISUAL ACUITY WITHOUT THE DISTORTION OR MAGNIFICATION THAT CAN RESULT FROMWEARING THICK-LENSED SPECTACLES OR CONTACT LENSES. HOWEVER,AS WITH ALL OTHER IMPLANTABLE DEVICES, THERE ARE PROBLEMS WITH THE INTERACTION OF THE SYNTHETIC LENSES WITH EYE TISSUES. INADVERTENT CONTACT BETWEEN THE LENS AND THE CORN ...

    SBIR Phase II 1987 Department of Health and Human Services
  3. A MULTICHANNEL WIDE-BAND BIOTELEMETRY SYSTEM

    SBC: DATA SCIENCES INTERNATIONAL, INC            Topic: N/A

    UNDER THIS PROPOSED EFFORT, THE FEASIBILITY OF A MULTICHANNEL FM TELEMETRY SYSTEM CAPABLE OF TELEMETERING WIDE-BAND PHYSIOLOGICAL DATA WILL BE STUDIED AND ALTERNATE DESIGNS WILL BE EVALUATED VIA THE CONSTRUCTIUON OF PROTOTYPES. THE SYSTEM WILL INCLUDE A TRANSMITTER CAPABLE OF TELEMETERING SIGNALS FROM COMMONLY USED ELECTRODES AS THE MAJOR FOCUS ON THIS EFFORT, WHILE INTEGRATING COMMERCIALLY AVAILA ...

    SBIR Phase II 1987 Department of Health and Human Services
  4. DETECTION OF THEOPHYLLINE USING A SIMPLE IMMUNOASSAY

    SBC: GENESIS LABORATORIES, INC            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS WORK IS TO DEVELOP A RAPID, COLORIMETRIC, INSTRUMENT-DEPENDENT ASSAY FOR THEOPHYLLINE CONSTITUENTS. GENESIS LABS' ""IMMUNOSTRIP'' ASSAY (PROTECTED BY PATENT) IS CONSTRUCTED IN A CONFIGURATION THAT IS APPLICABLE FOR THE RAPID DETECTION OF DRUGS AND METABOLITES IN BIOLOGICAL FLUIDS, E.G., URINE, BLOOD, OR SALIVA. THE RELATIVE SIMPLICITY OF THE METHOD SUGGESTS ITS EASY ...

    SBIR Phase II 1987 Department of Health and Human Services
  5. INTEGRATED OPTIC DEVICE FOR LASER BEAM SCANNING

    SBC: Apa Optics, Inc.            Topic: N/A

    MOST LASER SCANNING SYSTEMS ARE MECHANICAL, UTILIZING A MOTOR TO ROTATE A PRISM, MIRROR, OR HOLOGRAPHIC GRATING. SUCH MECHANICAL SYSTEMS ARE OR RELATIVELY LARGE SIZE AND MASS. THERE IS A NEED FOR A SOLID STATE SCANNING DEVICE WHICH WOULD OFFER BENEFITS OF REDUCED SIZE AND MASS, NO MOVING PARTS, IMPROVED RELIABILITY, LOW COSTS, AND LOW POWERREQUIREMENT. WE PROPOSE TO DEVELOP AN INTEGRATED OPTICS (I ...

    SBIR Phase II 1987 National Aeronautics and Space Administration
  6. TRANSMISSION HOLOGRAPHIC RELAY LENS FOR AIRCRAFT HEAD UP DISPLAY

    SBC: Apa Optics, Inc.            Topic: N/A

    THE OBJECTIVE OF THE PROPOSED EFFORT IS TO REDUCE THE SIZE, WEIGHT, AND COST OF THE RELAY OPTICS OF THE AIRCRAFT HEAD UP DISPLAY (HUD), BY REPLACING IT WITH TRANSMISSION HOLOGRAPHIC LENSES. HOLOGRAPHIC LENSES ARE VERY LIGHT AND CAN BE MANUFACTURED AT VERY LOW COSTS. APPLICATIONS OF HOLOGRAPHIC LENSES TO HUD WERE LIMITED IN THE PAST, DUE TO WIDE SPECTRAL BAND OF THE HUD - CATHODE RAY TUBE (CRT). HO ...

    SBIR Phase II 1987 Department of DefenseAir Force
  7. CHEMICAL INTELLIGENCE FOR AUTOMATED SYSTEMS: CHEMILUMINESCENT ENZYME IMMUNO ASSAY DEVICE FOR TOXINS

    SBC: SURMODICS, INC.            Topic: N/A

    A FEASIBILITY DEMONSTRATION PLAN IS PROPOSED FOR THE AFFINITY IMMOBILIZATION OF NON-CONSUMMABLE COMPONENTS OF A HOMOGENEOUS ENZYME IMMUNOASSAY SYSTEM, IN A FUNCTIONAL ARRANGEMENT WITH ONE ANOTHER ON A SILICA-BASED SENSOR SURFACE. THE BIOMEMBRANE CHEMICAL SENSOR DEVICE TO BE DEVELOPED THEREFROM, IS EXPECTED TO BE A FIELDABLE (SMALL AND RUGGED WITH LOW POWER AND CONSUMMABLE MATERIAL REQUIREMENTS) MU ...

    SBIR Phase II 1987 Department of DefenseNavy
  8. POWER-AUGMENTED EXOSKELETON DEMONSTRATION UNIT

    SBC: Prt Corp.            Topic: N/A

    THIS PROPOSAL DETAILS A DEVELOPMENT PROJECT WHICH WILL DEMONSTRATE FEASIBILITY OF A POWER-AUGMENTED EXOSKELETON. AN EXOSKELETON IS A JOINTED, EXTERNAL FRAMEWORK WORN BY A USER. FORCE SENSORS DETECT USER MOVEMENTS AND, THROUGH MODERN FEEDBACK CONTROL TECHNIQUES, POWER THE EXOSKELETON LIMBS. A USER'S STRENGTH CAN THUS BE MAGNIFIED THREE OR FIVE TIMES WITHOUT LOSS OF DEXTERITY OR SPEED. THE PROJECT I ...

    SBIR Phase II 1987 Department of DefenseAir Force
  9. ARCHITECTURE FOR A RECONFIGURABLE COMPUTER VISION SYSTEM

    SBC: Robert C. Fitch Consulting            Topic: N/A

    THE ARCHITECTURAL FEASIBILITY OF A GENERIC COMPUTER VISION SYSTEM COMPOSED OF HETEROGENEOUS PROCESSORS IS EXAMINED. THE STUDY FOCUSSES ON ISSUES SUCH AS THE NATURE OF THE HETEROGENEOUS PROCESSORS FUNCTIONAL CAPABILITIES, NETWORK REALIZATION TRADEOFFS, AND COMMON MODULE INTERFACES. THE GENERIC COMPUTER VISION SYSTEM IS DESIGNED TO MEET THE DEMANDS IMPOSED BY FUTURE INDUSTRIAL VISION APPLICATIONS, I ...

    SBIR Phase II 1987 National Science Foundation
  10. MAXIMIZING SHOOT FORMING EFFICIENCY OF POPULUS USING IN VITRO MICRO-CROSS SECTIONS

    SBC: Minn Vitro Inc.            Topic: N/A

    MICRO-CROSS SECTION (MCS) IS A NEW METHOD FOR MICROPROPAGATION (TISSUE CULTURE) OF SELECTED PLANTS WHICH SHOULD SIMULTANEOUSLY PROVIDE A DRAMATIC PER UNIT COST REDUCTION AND A LARGE INCREASE IN PLANT AVAILABILITY. BECAUSE OF A PROJECTED SEVERE SHORTFALL OF NATURALLY OCCURRING ASPEN FOR WOOD PRODUCTS INDUSTRIES WE HAVE SELECTED 2 ASPEN AND 4 HYBRID ASPEN GENOTYPES TO USE IN THE EVALUATION OF THIS T ...

    SBIR Phase II 1992 Department of Agriculture

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