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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. RNAi screening for Identification of Compounds to Induce Suspended Animation or Hypometabolism

    SBC: AGAVE BIOSYSTEMS INC.            Topic: N/A

    While the phenomenon of suspended animation has not been widely studied in humans, there are many anecdotal and medically verified examples of humans being in a state that is comparable to suspended animation when they have been accidentally nearly frozenfor short periods of time. There could be many advantages to inducing suspended animation or hypometabolism in humans such as extending survival ...

    SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
  2. Microorganism Imprinted Polymers (MOIPs) for Detection of Biological Warfare Agents

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    Radiation Monitoring Device, Inc. (RMD) will develop microorganism imprinted polymers (MOIPs) that purify, concentrate, and identify bacterial and viral wargare agents. In Phase I we will develop polymer formulations and fluorescent labeling strategiesfor MOIPs targeted towards E. coli and B. globigii vegetative cells. We will aslo demonstrate the feasibility of detecting biowarfare agents. In P ...

    SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
  3. Monitoring Food and Water for Pathogens

    SBC: BIOSCALE, INC.            Topic: N/A

    BioScale, Inc. was founded with the mission to develop biohazard detection systems for commercial applications. After an intensive investigation of technologies existing in commercial, academic, and government labs, BioScale has selected a MEMS device fordetection of viral and bacterial pathogens. This technology is best suited for the near-term development of a low-cost, field deployable, real- ...

    SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
  4. Short-Range Standoff UV Raman Chemical Imaging Detector

    SBC: ChemImage Sensor Systems            Topic: N/A

    ChemImage Corp. and ITT are proposing to demonstrate the feasibility of detecting and identifying chemical and biological threats using UV Raman Chemical Imaging techniques from a stand-off distance of 1 meter and against complex stationary backgroundmaterials such as asphalt and soil as commonly encountered by fielded military and homeland security personnel. The use of a standoff surface detect ...

    SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
  5. Colorimetric Sensors for End-of-Service-Life Indicators for Mask Filters

    SBC: CHEMMOTIF, INC.            Topic: N/A

    ChemMotif will develop, characterize and evaluate several colorimetric vapor sensors for application as end-of-service-life indicators for carbon-filter gas masks in Chemical and Biological Defense applications. These sensors include two general organicvapor sensors, one of which is sensitive to non-polar organics and the other to polar organics. A third sensor is designed to respond to acid gas ...

    SBIR Phase II 2003 Department of DefenseOffice for Chemical and Biological Defense
  6. Improved Protein Manufacturing in Insect Expression Systems

    SBC: Chesapeake Perl, Inc.            Topic: N/A

    Chesapeake PERL is a contract manufacturing company using the baculovirus expression system for mass production of proteins in lepidopterous insect larvae. PERL's automated in-line insect mass rearing and inoculation systems enables the production oflarge quantities of complex, biologically fully functional proteins. The baculovirus expression system as developed in the eighties and nineties is ...

    SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
  7. Microorganism Imprinted Polymers (MIOPs) for Detection of Biological Warfare Agents

    SBC: ECHO TECHNOLOGIES, INC.            Topic: N/A

    There is an immediate need for real-time sensitive and selective detection of biological warfare agents (BWA) in air or water. Essential components of developmental biological and chemical sensors are the molecular receptors or recognition elements.Molecular imprinting of polymers has been used with promising results to create artificial chemical receptors. Echo Technologies, Inc. proposes to de ...

    SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
  8. Yeast Based Biosensor for Oganophosphate Detection

    SBC: Luna Innovations Incorporated            Topic: N/A

    There exists a military and homeland security need for rapid, accurate and sensitive methods for the detection of organophosphates in cluttered environments. The in vitro modification and selection (IVMS) process under development by the Luna teamovercomes the limitations of current biosensor technologies by converting a known biomolecular sensor - the receptor for a steroid hormone - into a new ...

    SBIR Phase II 2003 Department of DefenseOffice for Chemical and Biological Defense
  9. Novel Surface Modification Technologies for Improved Chemical Biological (CB) Protective Materials

    SBC: GVD Corporation            Topic: N/A

    GVD proposes to develop a lightweight, durable, breathable, water- and chemical-resistant treatment for fabrics, specifically for the military battledress overgarment. GVD will employ its nanotechnology developed at MIT by company founders, a unique hotfilament chemical vapor deposition process (HFCVD), to create ultra-thin, highly engineered fluoropolymer and fluorosilicone coatings for fibrous ...

    SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
  10. Molecular Signatures of Biological Pathogens

    SBC: ILLUMIGEN BIOSCIENCES, INC.            Topic: N/A

    This Phase II continuation of ongoing research aims to extend our existing database of human molecular response to infection with biological pathogens. We will compile gene expression changes that are predictive of infection with a larger variety ofbacterial and viral pathogens. The ultimate goal is to perform analyses that may form the basis for a commercial microarray product aimed at early an ...

    SBIR Phase II 2003 Department of DefenseOffice for Chemical and Biological Defense

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