Award Data

THE LONG-RANGE GOAL OF THIS PROGRAM IS THE DEVELOPMENT AND COMMERCIALIZATION OF PROTON ACCELERATORS SUITABLE FOR RADIATION THERAPY OF CANCER IN HOSPITAL OR CLINICAL SETTINGS. FOR THIS PURPOSE THE ACCELERATOR SHOULD HAVE AN ENERGY UP TO 250 MEV, AND MUST BE SIMPLE, RELIABLE, AND INEXPENSIVE COMPARED TO EXISTING ACCELERATORS FOR PHYSICS APPLICATIONS. IN ADDITION, WITH SUFFICIENT INNOVATION, IT COULD ...

THE ROLLER PUMP, USED TO PUMP BLOOD FLOW DURING CARDIOPULMONARY BYPASS AND TO PROVIDE LONG-TERM CIRCULATORY SUPPORT, IS A CONSTANT-BLOOD-FLOW DEVICE. IT MAINTAINS CONSTANT FLOW INDEPENTLY OF THE CLINICALLY EXPECTED CHANGES IN INLET PRESSURES. A DECREASE IN BLOOD SUPPLY TO THE INLET OF THE PUMP WITHOUT A CONCOMITANT DECREASE IN PUMP SPEED CAN CAUSE EXCESSIVE SUCTION LEADING TO AIR EMBOLISM, THROMBO ...

IT IS PROPOSED TO DETERMINE THE FEASIBILITY OF USING A NONEQUILIBRIUM PLASMA JET, DEVELOPED AT AEROCHEM OVER THE PAST QUARTER CENTURY, AS A MEANS OF ENHANCING IGNITION AND FLAME STABILIZATION IN AIR-BREATHING ENGINES AND IN SUPERSONIC COMBUSTION. SPECIFICALLY, WE WILL DETERMINE; IF IGNITION OF LEAN OR LOW PRESSURE MIXTURES CAN BE MADE MORE RELIABLE; IF FLAME HOLDING LIMITS CAN BE BROADENED, E.G., ...

THE GENERIC ARTIFICIAL INTELLIGENCE EXPERT SYSTEM FOR SPACE-STATION APPLICATIONS WILL BE USER-FRIENDLY AND WILL UTILIZE A HIERARCHY OF FRAMES FOR DATA INPUT, AUTOMATIC FAULT DIAGNOSIS AND ANALYSIS AND REPAIR FUNCTIONS. IT WILL PROVIDE PROMPT DIAGNOSIS AND SUGGESTIONS FOR SYSTEM REPAIR. IT WILL PROVIDE AS MUCH AUTOMATION AS POSSIBLE FOR REPAIR FUNCTIONS. THE DESIGN WILL BE APPROPRIATE FOR INTERFACI ...

BIR PROPOSES AN INNOVATIVE PORTABLE X-RAY DETECTION AND MEASUREMENT SYSTEM FOR NDE APPLICATIONS. BASED ON A FILMLESS CASSETTE OF DISCRETE DIGITAL X-RAY DECECTORS, SUCH A SYSTEM WOULD ENABLE DIRECT DIGITAL IMAGING FOR VIEWING, VCR RECORDING, OR FOR COMPUTER ANALYSIS. THE SYSTEM WOULD RESEMBLE A FILM CASSETTE IN ITS PORTABILITY AND IMAGE SENSITIVITY AND RESOLUTION. WE PROPOSE TO CAREFULLY EVALUATE T ...

THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP QUANTITATIVE ESTROGEN RECEPTOR CONCENTRATION MEASUREMENTS USING HIGH- RESOLUTION DIGITAL IMAGE MICROSCOPY TECHNIQUES. THE TECHNIQUES WILL ENABLE DIRECT MEASUREMENTS OF RECEPTOR CONCENTRATION ON A CELL-BY-CELL BASIS. THIS IS AN IMPROVEMENT OVER THE CURRENT BIOCHEMICAL ASSAYS, WHICH GIVE ONLY AN AVERAGE VALUE FOR RECEPTOR CONCENTRATION. THE QUANTITATIVE AS ...

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THE PRIME LONG-TERM OBJECTIVE OF THIS PROJECT IS TO UPDATE, ENHANCE, AND DISTRIBUTE TWO COMPUTER PROGRAMS UTILIZING THE UNIQUE MULTIVARIATE ANALYSIS TECHNIQUES DEVELOPED BY THE PSYCHOLOGIST ROBERT TRYON WITH NIH SUPPORT DURING THE 1960S. ONE LONG-TERM GOAL IS TO PRODUCE AN ENHANCED ALL-FORTRAN VERSION OF A MAIN BCTRY82 SYSTEM, PORTABLE TO MOST LARGE COMPUTERS. A SECOND LONG-TERM GOAL IS TO PRODUCE ...

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