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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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C-arm Fluoroscopy for Prostate Brachytherapy
SBC: BURDETTE MEDICAL SYSTEMS, INC. Topic: N/ADESCRIPTION (provided by applicant): A technique is proposed for the development of an intraoperative, 3-dimensional registration of C-arm fluoroscopic images with spatially-registered ultrasound visualization and implant guidance of radioactive implants and on-line implant assessment during the procedure for treatment of prostate cancer. With present techniques using transrectal ultrasound guidan ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Design & Synthesis of Novel Agents to Treat Amyloidosis
SBC: Advanced Life Sciences, Inc. Topic: N/ADESCRIPTION (provided by applicant): The major goal of our proposed project is to advance the development of novel compounds for the treatment of amyloidosis and other protein aggregation diseases. Preliminary work demonstrated that two chalcones inhibited amyloid fibril formation, in vitro, and that further work is warranted. The amyloid diseases that arise from nonimmunoglobulin proteins includ ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
A new PCR-based method for HIV detection
SBC: ALLIED INNOVATIVE SYSTEMS Topic: N/ADESCRIPTION (provided by applicant): The objective of this proposal is to demonstrate the feasibility of a new approach to improving the performance of PCR-based methods for HIV detection A new technology allows one to increase the sensitivity, accuracy, dynamic range, signal-to-noise ratio, save costly reagents and reduce time of analysis This unique approach has never been used before for imp ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Potential Brain Therapeutics
SBC: AMERICAN BIOTECHNOLOGY RESEARCH CORP Topic: N/ADESCRIPTION (provided by applicant): Use of botanical products such as exogenous antioxidants has gained considerable momentum in the last few years in therapy of human degenerative diseases. Among these antioxidants, tumeric, neem, guggul, alpha-tocopherol, Beta-carotene, and ascorbic acid have been shown to have a special relevance in maintaining the redox e ...
SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health -
Emerging Weapons Technology Evaluation Model
SBC: APPLIED SCIENCES LABORATORY, INC. Topic: N/AAccelerated development of directed energy technologies has presented new problems to mission planners and weapon operators regarding the capabilities, lethality and performance of weapon systems. The Emerging Weapons Technology Evaluation Model willaddress these shortcomings by providing users of varying technical expertise 1) the ability to model a variety of weapons in various mission scenario ...
SBIR Phase I 2003 Department of DefenseSpecial Operations Command -
Optical Trapping
SBC: Arryx, Inc. Topic: N/ADESCRIPTION (provided by applicant): Manipulation of objects on a microscopic scale can be done conveniently with a device known as a laser or optical tweezers. While laser trapping was originally devised for trapping Rayleigh particles (i.e. particles much less than the wavelength of the incident light) it's ability to manipulate biological particles such as macromolecules, viruses, microtubul ...
SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health -
Molecular Manipulation with a Holographic Laser Tweezers
SBC: Arryx, Inc. Topic: N/ADESCRIPTION (provided by applicant): Manipulation of objects on a microscopic scale can be done conveniently with a device known as a laser or optical tweezers. While laser trapping was originally devised for trapping Rayleigh particles (i.e. particles much less than the wavelength of the incident light) it's ability to manipulate biological particles such as macromolecules, viruses, microtuble ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Comprehensive aneuploidy diagnosis in single cells
SBC: ART INSTITUTE OF NEW YORK AND NEW JERSEY Topic: N/ADESCRIPTION (provided by applicant): The objective of the proposed research is to develop clinically applicable DNA microarray methods for detecting chromosome imbalance (e.g. aneuploidy) in isolated cells. Such tests will be widely applicable and we anticipate their use in several areas: 1) non-invasive prenatal testing based on the analysis of small numbers of fetal cells isolated from the mater ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Cartilage Repair by Engineered Implant Feasibility study
SBC: ARTICULAR ENGINEERING, LLC Topic: N/ADESCRIPTION (provided by applicant): This small business Innovation Research Phase I project proposes to define methodology to facilitate the growth of engineered cartilage tissue. Recent studies have demonstrated that the alginate recovered chondrocyte (ARC) method can be used to stimulate isolated adult articular chondrocytes in vitro to form viable cartilaginous tissue with good physiochemical ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Effective Oral Iron Supplement for Pre-dialysis Patients
SBC: BIOCHEMANALYSIS CORPORATION Topic: N/ADESCRIPTION (provided by applicant): Development of anemia is a major problem in chronic renal failure. Its prevention/early treatment with recombinant human erythropoietin (rHuEpo) during pre-dialysis phase is important. Available iron is required for efficient action of rHuEpo; iron supplements are often needed; oral iron therapy is the preferred mode. Availability of oral iron varies widely in ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health