Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. DESIGN OF A PROTON MEDICAL ACCELERATOR

    SBC: Acctek Associates, Inc.            Topic: N/A

    THE LONG-RANGE GOAL OF THIS PROGRAM IS THE DEVELOPMENT AND COMMERCIALIZATION OF PROTON ACCELERATORS SUITABLE FOR RADIATION THERAPY OF CANCER IN HOSPITAL OR CLINICAL SETTINGS. FOR THIS PURPOSE THE ACCELERATOR SHOULD HAVE AN ENERGY UP TO 250 MEV, AND MUST BE SIMPLE, RELIABLE, AND INEXPENSIVE COMPARED TO EXISTING ACCELERATORS FOR PHYSICS APPLICATIONS. IN ADDITION, WITH SUFFICIENT INNOVATION, IT COULD ...

    SBIR Phase II 1987 Department of Health and Human Services
  2. A SELF-REGULATING PUMP CHAMBER FOR STANDARD ROLLER PUMPS

    SBC: Adam Spence Corpon            Topic: N/A

    THE ROLLER PUMP, USED TO PUMP BLOOD FLOW DURING CARDIOPULMONARY BYPASS AND TO PROVIDE LONG-TERM CIRCULATORY SUPPORT, IS A CONSTANT-BLOOD-FLOW DEVICE. IT MAINTAINS CONSTANT FLOW INDEPENTLY OF THE CLINICALLY EXPECTED CHANGES IN INLET PRESSURES. A DECREASE IN BLOOD SUPPLY TO THE INLET OF THE PUMP WITHOUT A CONCOMITANT DECREASE IN PUMP SPEED CAN CAUSE EXCESSIVE SUCTION LEADING TO AIR EMBOLISM, THROMBO ...

    SBIR Phase I 1987 Department of Health and Human Services
  3. QUANTITATION OF ESTROGEN CONCENTRATION IN CELLS

    SBC: Cell Analysis Systems Inc.            Topic: N/A

    THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP QUANTITATIVE ESTROGEN RECEPTOR CONCENTRATION MEASUREMENTS USING HIGH- RESOLUTION DIGITAL IMAGE MICROSCOPY TECHNIQUES. THE TECHNIQUES WILL ENABLE DIRECT MEASUREMENTS OF RECEPTOR CONCENTRATION ON A CELL-BY-CELL BASIS. THIS IS AN IMPROVEMENT OVER THE CURRENT BIOCHEMICAL ASSAYS, WHICH GIVE ONLY AN AVERAGE VALUE FOR RECEPTOR CONCENTRATION. THE QUANTITATIVE AS ...

    SBIR Phase II 1987 Department of Health and Human Services
  4. A RESORBABLE COLLAGEN PROSTHESES FOR REPAIR

    SBC: Colla-tec, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  5. UPDATING THE TRYON MULTIVARIATE ANALYSIS COMPUTER SYSTEM

    SBC: D2 Associates            Topic: N/A

    THE PRIME LONG-TERM OBJECTIVE OF THIS PROJECT IS TO UPDATE, ENHANCE, AND DISTRIBUTE TWO COMPUTER PROGRAMS UTILIZING THE UNIQUE MULTIVARIATE ANALYSIS TECHNIQUES DEVELOPED BY THE PSYCHOLOGIST ROBERT TRYON WITH NIH SUPPORT DURING THE 1960S. ONE LONG-TERM GOAL IS TO PRODUCE AN ENHANCED ALL-FORTRAN VERSION OF A MAIN BCTRY82 SYSTEM, PORTABLE TO MOST LARGE COMPUTERS. A SECOND LONG-TERM GOAL IS TO PRODUCE ...

    SBIR Phase II 1987 Department of Health and Human Services
  6. ULTRASOUND DOPPLER/B-MODE BREAST SCANNER

    SBC: Daltex Medical Sciences Inc.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  7. CYTOMEGALOVIRUS DETECTION USING NONRADIOACTIVE DNA PROBES IN SITU

    SBC: Ert            Topic: N/A

    CYTOMEGALOVIRUS (CMV), A MEMBER OF THE HERPES VIRUS GROUP, IS PRESENT IN THE BLOOD OF A LARGE PORTION OF THE HUMAN POPULATION. ADMINISTRATION OF THIS BLOOD TO HIGH-RISK PATIENTS MAY RESULT IN DEATH. ENZO PROPOSES THE DEVELOPMENTOF A QUICK, SPECIFIC, EASY AND ECONOMICAL DIAGNOSTIC TEST, BASED ON NONRADIOACTIVE DNA-DNA HYBRIDIZATION, TO DIRECTLY SCREEN HUMAN BLOOD FOR CMV. PHASE I DEVELOPMENT WILL B ...

    SBIR Phase II 1987 Department of Health and Human Services
  8. AMINO ACID-DEGRADING ENZYMES AS ANTICANCER AGENTS

    SBC: Ert            Topic: N/A

    ENZON, INC. IS INVOLVED IN THE DEVELOPMENT OF THERAPEUTIC ENZYMES FOR HUMAN AND VETERINARY USE. MANY ENZYMES HAVE SHOWN EFFECTIVENESS AS ANTICANCER AGENTS ON INITIAL INJECTION, BUT THEIR IMMUNOGENICITY AND SHORT PLASMA HALF-LIFE HAVE PREVENTED EXPLOITATION OF THEIR POTENTIAL. ENZON, INC. WILL MODIFY TWO GLUTAMINASE-ASPARAGINASES AND A HISTIDASE USING A PATENTED COMPANY PROCESS TO PRODUCE ENZYME-PO ...

    SBIR Phase I 1987 Department of Health and Human Services
  9. DEVELOPMENT OF A DATABASE ON UNPROVED CANCER TREATMENTS

    SBC: I. S. Grupe, Inc.            Topic: N/A

    THE OBJECTIVE OF THIS PROGRAM IS TO ESTABLISH A METHOD BY WHICH CANCER TREATMENTS NOT BEING INVESTIGATED THROUGH CONVENTIONAL CHANNELS CAN BE IDENTIFIED, ORGANIZED INTO A DATABASE, AND DISSEMINATED TO INTERESTED PARTIES. ORGANIZING THIS INFORMATION WILL PROVIDE A MEANS FOR IDENTIFYING UNSCRUPULOUS METHODS AND ALLOW THOSE TREATMENTS WITH PROMISE TO BE BROUGHT TO CLINICAL TRIALS. AN IMMEDIATE GOAL O ...

    SBIR Phase I 1987 Department of Health and Human Services
  10. DEVELOPMENT OF A SCIENTIFIC SUMMARY LANGUAGE-MEDLISH

    SBC: I. S. Grupe, Inc.            Topic: N/A

    CURRENT SCIENTIFIC BIBLIOGRAPHIC DATABASES (E.G., MEDLINE) NOW PLAY A CENTRAL ROLE IN LITERATURE ACTIVITIES. THEY ARE IMPORTANT AND THEY ARE WIDELY USED. HOWEVER, THE INFORMATION EXPRESSED IN THE TITLE, ABSTRACT, AND MESH INDEXFIELDS IN THESE DATABASES IS QUITE CHAOTIC AND SKETCHY COMPARED WITH THE STRUCTURE OF MANY OTHER KINDS OF DATABASES. BECAUSE OF THESE DEFICIENCIES, COMPUTERIZED LITERATURE S ...

    SBIR Phase I 1987 Department of Health and Human Services
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