Award Data

This proposal focuses on the design and realization of a Rapid Development Environment (RDE) for synthesizing Physiological Diagnostic Systems. A high level of productivity will be reached through the development of libraries of sensors, and of elementaryand complex physiology models. The user will compose a diagnostic algorithm and system prototype by combining building blocks thorough an intelli ...

A Diesel driven high efficiency, portable thermoelectric generator capable of producing 500 Watts, scalable to 1500 Watts will be designed at Hi-Z Technology. The unit will supply uninterruptible power at 28 VDC for a minimum of 8 hours. The generatorwill be capable of starting and operating from -32 oC to + 52 oC. The unit system efficiency will be over 10%, it will exhibit a suppressed infrar ...

Multilayer chemical protective gloves that provide 24 hours of protection against chemical warfare agents while being more resistant to petroleum oils and flames than the currently used butyl rubber gloves will be developed. This will be achieved usingaqueous nanocomposite elastomeric coatings specially formulated for use in newly designed multilayer gloves. In phase 1, InMat demonstrated that a f ...

IST is proposing the development of a miniature chemical agent detection device that is based on using infrared energy absorption to detect the presence of toxic materials. The detection of toxic chemicals is possible if the vapors pass between a source ofinfrared energy and a sensor capable of measuring the thermal change associated with the absorption of infrared energy at specific frequencies. ...

There is a critical need for rapid, accurate measurement of serum cholinesterase activity in the field to provide a timely determination of nerve agent exposure. The overall objective of the project is to develop an easy-to-use analytical system consistingof small, inexpensive (and therefore disposable) silicon microchips used with a portable instrument, thus permitting field cholinesterase measur ...

The proposed work will develop a silicon microchip containing an array of synthetic globular DNA affinity recognition elements selected for binding pathogens, toxins, or other protein-based biothreats to enable their detection in the field. For readout, a

NOVELX, Inc. proposes to develop and market a compact scanning electron microscope (SEM) with X-ray analysis capabilities for mobile, homeland defense, commercial, and military applications. The Phase I technical objective is to investigate the feasibilityof integrating a miniature modular scanning electron microscope (mmSEM) with a thermoelectrically cooled silicon X-ray detector, in order to pro ...

In response to CBD need, Physical Optics Corporation (POC) proposes to develop and fabricate a novel Microfluidic Array Biosensor (MICAB) as a new, sensitive, simple-to-use, hybrid instrument system for the early and rapid detection of environmentalbacterial and viral pathogens. The concept of the system is based on the combination of microfluidics and evanescent wave phenomena. The MICAB will c ...

Our overall goal in this project is to make available inexpensive neutralizing antibodies against Botulinum neurotoxin (BoNT) in large quantity, using transgenic plants. Dr. James Marks (UC San Francisco School of Medicine) has identified murine and humansingle chain Fv (scFv) that bind non-overlapping epitopes on BoNT/A and neutralize toxin in vitro and in vivo. At present, plants offer the best ...

POLYMERight proposes to develop field repair kits that will prevent the compromise of collective protection systems if their integrity is lost. The adhesive chemistry utilized can quickly, easily and dependably bond the like and unlike surfaces together,including Kevlar, polyfluorinated materials, polyolefins, PVC and other materials associated with collective protection systems. It will be teste ...